Newgreen Factory Supply Topotecan Hydrochloride High Quality 99% Topotecan Hydrochloride Powder
Mafotokozedwe Akatundu
Topotecan Hydrochloride ndi mankhwala a chemotherapy omwe amagwiritsidwa ntchito makamaka pochiza mitundu ina ya khansa. Ndi mtundu wa hydrochloride wa topotecan, topoisomerase inhibitor yomwe imagwira ntchito makamaka poletsa ntchito ya DNA topoisomerase I.
Ndemanga:
Mukamagwiritsa ntchito Topotecan, odwala ayenera kutsogoleredwa ndi dokotala, makamaka kwa odwala omwe ali ndi vuto la chiwindi ndi impso kapena matenda ena. Kuyeza magazi nthawi zonse kumafunika panthawi ya chithandizo kuti muwone zotsatira zake.
Pomaliza, Topotecan Hydrochloride ndi mankhwala oletsa khansa, omwe amagwiritsidwa ntchito makamaka pochiza khansa ya m'mawere ndi khansa yaing'ono ya m'mapapo ya m'mapapo, ndipo ili ndi phindu lalikulu lachipatala.
COA
| Zinthu | Zofotokozera | Zotsatira |
| Maonekedwe | Zoyera-zoyera kapena ufa woyera | Ufa Woyera |
| Chizindikiro cha HPLC | Mogwirizana ndi zomwe zanenedwa nthawi yosunga zinthu pachimake | Zimagwirizana |
| Kuzungulira kwachindunji | + 20.0.-+22.0. | + 21. |
| Zitsulo zolemera | ≤ 10ppm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Kutaya pakuyanika | ≤ 1.0% | 0.25% |
| Kutsogolera | ≤3 ppm | Zimagwirizana |
| Arsenic | ≤1ppm | Zimagwirizana |
| Cadmium | ≤1ppm | Zimagwirizana |
| Mercury | ≤0. 1 ppm | Zimagwirizana |
| Malo osungunuka | 250.0℃~265.0℃ | 254.7 ~ 255.8℃ |
| Zotsalira pakuyatsa | ≤0. 1% | 0.03% |
| Hydrazine | ≤2 ppm | Zimagwirizana |
| Kuchulukana kwakukulu | / | 0.21g/ml |
| Kachulukidwe kachulukidwe | / | 0.45g/ml |
| Kuyesa(Topotecan Hydrochloride） | 99.0% ~ 101.0% | 99.65% |
| Chiwerengero chonse cha ma aerobes | ≤1000CFU/g | <2CFU/g |
| Nkhungu & Yisiti | ≤100CFU/g | <2CFU/g |
| E.coli | Zoipa | Zoipa |
| Salmonella | Zoipa | Zoipa |
| Kusungirako | Sungani pamalo ozizira & owuma, sungani kuwala kolimba. | |
| Mapeto | Woyenerera | |
Ntchito
Topotecan Hydrochloride ndi mankhwala a chemotherapy omwe amagwiritsidwa ntchito makamaka pochiza mitundu ina ya khansa. Ndi topoisomerase inhibitor yokhala ndi njira zotsatirazi zochitira ndi ntchito:
Ntchito:
1.Topoisomerase inhibition: Topotecan imasokoneza kubwereza kwa DNA ndi kulembedwa mwa kulepheretsa ntchito ya topoisomerase I. Kuletsa kumeneku kumayambitsa kusweka kwa maunyolo a DNA, motero kulepheretsa kufalikira kwa maselo a khansa.
2. Antitumor ntchito: Topotecan amagwiritsidwa ntchito makamaka pochiza khansa ya ovarian, khansa yaing'ono ya m'mapapo ya m'mapapo ndi mitundu ina ya lymphoma. Atha kugwiritsidwa ntchito ngati mankhwala oyamba kapena ngati njira yachiwiri mankhwala ena akalephera.
3.Kukhazikika kwa ma cell: Zotsatira za Topotecan pamaselo a selo makamaka zimachitika mu gawo la S ndi gawo la G2, zomwe zimapangitsa kuti zikhale ndi mphamvu yakupha pa maselo a khansa mu gawo linalake la kukula kwa maselo.
4.Kuphatikiza mankhwala: Topotecan ingagwiritsidwe ntchito limodzi ndi mankhwala ena a chemotherapy kuti apititse patsogolo mphamvu ya anti-chotupa ndikuwongolera kuyankha kwa wodwalayo.
5.Perekani Zizindikiro: Nthawi zina, kugwiritsa ntchito Topotecan kungathandize kuthetsa zizindikiro zokhudzana ndi khansa komanso kusintha moyo wa wodwalayo.
Ndemanga:
Topotecan angayambitse mavuto ena, kuphatikizapo nseru, kusanza, kutopa, leukopenia, ndi zina zotero. Mukamagwiritsa ntchito mankhwalawa, odwala ayenera kuyang'aniridwa ndi kuyang'aniridwa ndi dokotala.
Pomaliza, Topotecan Hydrochloride ndi mankhwala oletsa khansa omwe amakhala ndi zotsatira zake zotsutsana ndi zotupa makamaka poletsa DNA topoisomerase I.
Kugwiritsa ntchito
Topotecan Hydrochloride ndi mankhwala a chemotherapy omwe amagwiritsidwa ntchito makamaka pochiza mitundu ina ya khansa. Zotsatirazi ndizo ntchito zake zazikulu:
1. Khansa ya m'chiberekero: Topotecan amagwiritsidwa ntchito pochiza khansa ya m'mawere yobwerezabwereza, makamaka kwa odwala pambuyo pa chithandizo china (monga platinamu-based chemotherapy) yalephera. Itha kugwiritsidwa ntchito ngati wothandizira limodzi kapena kuphatikiza ndi mankhwala ena.
2. Khansa yaing'ono ya m'mapapo: Mankhwalawa amagwiritsidwanso ntchito pochiza khansa yaing'ono ya m'mapapo ya m'mapapo, kawirikawiri ngati njira yachiwiri yothandizira, makamaka pamene matendawa ayambiranso pambuyo poyambira mankhwala amphamvu.
3.Makhansa Ena: Ngakhale kuti Topotecan imagwiritsidwa ntchito makamaka pa khansa ya ovarian ndi khansa yaing'ono ya m'mapapo, ikuphunziridwanso m'mayesero ena achipatala a mitundu ina ya khansa, monga khansa ya khomo lachiberekero, khansa ya pancreatic, ndi mitundu ina ya lymphoma.
4.Mayesero azachipatala: Topotecan akuwunikidwanso m'mayesero azachipatala a khansa zosiyanasiyana kuti aphunzire momwe amachitira komanso chitetezo chake pazosankha zosiyanasiyana.
5.Combination TherapyNthawi zina, Topotecan itha kugwiritsidwa ntchito limodzi ndi mankhwala ena a chemotherapy kapena mankhwala ochizira omwe akuwongolera kuti achire.
Ndemanga:
Mukamagwiritsa ntchito Topotecan, odwala ayenera kutsogoleredwa ndi dokotala, makamaka kwa odwala omwe ali ndi vuto la chiwindi ndi impso kapena matenda ena. Kuyeza magazi nthawi zonse kumafunika panthawi ya chithandizo kuti muwone zotsatira zake.
Pomaliza, Topotecan Hydrochloride ili ndi phindu lofunikira pakuchiza khansa, makamaka pakuwongolera khansa ya ovarian yobwerezabwereza komanso khansa yaing'ono ya m'mapapo.
Phukusi & Kutumiza
