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Mafotokozedwe Akatundu
Famotidine ndi H2 receptor antagonist, yomwe imagwiritsidwa ntchito makamaka pochiza matenda okhudzana ndi chapamimba acid. Imalepheretsa ma receptors a histamine H2 m'maselo am'mimba a parietal, amachepetsa katulutsidwe ka asidi m'mimba, motero amachepetsa zizindikiro zobwera chifukwa cha kuchuluka kwa asidi m'mimba. Zotsatirazi ndikuyambitsa mwatsatanetsatane kwa Famotidine:
Main Features ndi Ntchito
1.Njira: Famotidine amalepheretsa katulutsidwe ka asidi m'mimba ndipo amachepetsa acidity m'mimba mwa kusankha antagonizing zolandilira H2 pa chapamimba parietal maselo.
2. Zizindikiro:
- Matenda a Reflux a Gastroesophageal (GERD): Amagwiritsidwa ntchito kuthetsa zizindikiro zomwe zimayambitsidwa ndi asidi reflux, monga kutentha kwa mtima ndi kutsekemera kwa asidi.
-Chilonda cham'mimba: chimagwiritsidwa ntchito pochiza zilonda zam'mimba ndi zilonda zam'mimba komanso kulimbikitsa kuchira.
-Kupewa Matenda Okhudzana ndi Matenda a M'mimba: Nthawi zina, Famotidine ingagwiritsidwe ntchito pofuna kupewa matenda okhudzana ndi m'mimba chifukwa cha mankhwala monga NSAIDs.
3. Fomu ya mlingo:Famotidine nthawi zambiri imapezeka m'mapiritsi ndi jakisoni, ndipo odwala amatha kumwa motsatira malangizo a dokotala.
4.Zoyipa:Famotidine nthawi zambiri imalekerera bwino, koma zotsatira zina zimatha kuchitika, monga mutu, chizungulire, kutsegula m'mimba kapena kudzimbidwa.
5. Malangizo ogwiritsira ntchito:Pogwiritsira ntchito Famotidine, odwala ayenera kudziwitsa madokotala awo ngati ali ndi mavuto ena azaumoyo kapena akumwa mankhwala ena kuti asagwirizane ndi mankhwala.
Fotokozerani mwachidule
Famotidine ndiwothandiza kwambiri polimbana ndi H2 receptor antagonist, omwe amagwiritsidwa ntchito makamaka pochiza matenda okhudzana ndi asidi am'mimba, monga gastroesophageal reflux matenda ndi zilonda zam'mimba. Pochepetsa kutulutsa kwa asidi m'mimba, Famotidine imatha kuthetsa zizindikiro zofananira ndikulimbikitsa machiritso. Mukamagwiritsa ntchito, muyenera kutsatira malangizo a dokotala kuti muwonetsetse kuti ndinu otetezeka komanso ogwira mtima.
COA
| Zinthu | Zofotokozera | Zotsatira |
| Maonekedwe | Zoyera-zoyera kapena ufa woyera | Ufa Woyera |
| Chizindikiro cha HPLC | Mogwirizana ndi zomwe zanenedwa nthawi yosunga zinthu pachimake | Zimagwirizana |
| Kuzungulira kwachindunji | + 20.0.-+22.0. | + 21. |
| Zitsulo zolemera | ≤ 10ppm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Kutaya pakuyanika | ≤ 1.0% | 0.25% |
| Kutsogolera | ≤3 ppm | Zimagwirizana |
| Arsenic | ≤1ppm | Zimagwirizana |
| Cadmium | ≤1ppm | Zimagwirizana |
| Mercury | ≤0. 1 ppm | Zimagwirizana |
| Malo osungunuka | 250.0 ℃ ~ 265.0 ℃ | 254.7 ~ 255.8 ℃ |
| Zotsalira pakuyatsa | ≤0. 1% | 0.03% |
| Hydrazine | ≤2 ppm | Zimagwirizana |
| Kuchulukana kwakukulu | / | 0.21g/ml |
| Kachulukidwe kachulukidwe | / | 0.45g/ml |
| Mayeso (Famotidine) | 99.0% ~ 101.0% | 99.65% |
| Chiwerengero chonse cha ma aerobes | ≤1000CFU/g | <2CFU/g |
| Nkhungu & Yisiti | ≤100CFU/g | <2CFU/g |
| E.coli | Zoipa | Zoipa |
| Salmonella | Zoipa | Zoipa |
| Kusungirako | Sungani pamalo ozizira & owuma, sungani kuwala kolimba. | |
| Mapeto | Woyenerera | |
Ntchito
Famotidine ndi H2 receptor antagonist, yomwe imagwiritsidwa ntchito makamaka pochiza matenda okhudzana ndi chapamimba acid. Zimagwira ntchito poletsa ma receptor a histamine H2 m'maselo am'mimba a parietal, kuchepetsa kutuluka kwa asidi m'mimba. Zotsatirazi ndi ntchito zazikulu za Famotidine:
1. Chepetsani kutulutsa kwa asidi m'mimba:Famotidine imachepetsa kwambiri katulutsidwe ka asidi m'mimba mwa kusokoneza ma receptor a H2, zomwe zimathandiza kuthetsa zizindikiro zomwe zimayambitsidwa ndi asidi wambiri wa m'mimba.
2. Chithandizo cha matenda a reflux a gastroesophageal (GERD):Famotidine angagwiritsidwe ntchito pochiza matenda a reflux a gastroesophageal, kuchepetsa kutentha kwa mtima komanso kusapeza bwino chifukwa cha m'mimba acid reflux.
3. Chithandizo cha zilonda zam'mimba:Famotidine amagwiritsidwa ntchito pochiza zilonda zam'mimba ndi zilonda zam'mimba, kulimbikitsa machiritso a zilonda, komanso kuchepetsa chiopsezo chobwereranso.
4. Kupewa kwa postoperative asidi chapamimba katulutsidwe:Pambuyo pa maopaleshoni ena, Famotidine angagwiritsidwe ntchito kuteteza kuchulukitsitsa kwa asidi m'mimba ndikuchepetsa chiopsezo cha zovuta zapambuyo pa opaleshoni.
5. Relieve zizindikiro zokhudzana ndi asidi m'mimba:Famotidine ingathandize kuthetsa zizindikiro zomwe zimayambitsidwa ndi asidi m'mimba, monga kupweteka kwa m'mimba, kusanza ndi kutupa.
Kugwiritsa ntchito
Famotidine nthawi zambiri imapezeka mu mawonekedwe a mapiritsi kapena jakisoni, ndipo mlingo weniweni ndi kuchuluka kwa ntchito ziyenera kusinthidwa malinga ndi malangizo a dokotala.
Zoipa
Famotidine nthawi zambiri amalekerera bwino, koma zotsatira zina zimatha kuchitika, monga mutu, chizungulire, kutsegula m'mimba, kapena kudzimbidwa.
Pomaliza, Famotidine ndiwothandiza kwambiri H2 receptor antagonist, makamaka amagwiritsidwa ntchito pochiza matenda okhudzana ndi asidi am'mimba, kuthandiza odwala kuthetsa zizindikiro ndikulimbikitsa machiritso. Mukamagwiritsa ntchito, muyenera kutsatira malangizo a dokotala kuti muwonetsetse kuti ndinu otetezeka komanso ogwira mtima.
Kugwiritsa ntchito
Kugwiritsiridwa ntchito kwa Famotidine kumangoganizira kwambiri za matenda okhudzana ndi chapamimba acid, kuphatikizapo zotsatirazi:
1. Matenda a Reflux a Gastroesophageal Reflux (GERD):Famotidine amagwiritsidwa ntchito pochotsa zizindikiro zomwe zimayambitsidwa ndi acid reflux, monga kutentha kwa mtima, acid regurgitation, ndi kupweteka pachifuwa. Zimathetsa zizindikirozi mwa kuchepetsa katulutsidwe ka asidi m'mimba.
2. Chilonda cha m'mimba:Famotidine amagwiritsidwa ntchito pochiza zilonda zam'mimba ndi zilonda zam'mimba, zomwe zimathandiza kulimbikitsa machiritso a zilonda zam'mimba komanso kuchepetsa ululu ndi kusapeza bwino.
3.Kupewa matenda okhudzana ndi asidi am'mimba:Famotidine ingagwiritsidwe ntchito kuteteza matenda okhudzana ndi asidi am'mimba omwe amayamba chifukwa cha mankhwala monga nonsteroidal anti-inflammatory drugs (NSAIDs), makamaka odwala omwe ali pachiopsezo chachikulu.
4.Zollinger-Ellison syndrome:Famotidine itha kugwiritsidwanso ntchito pochiza matenda osowawa, omwe amayambitsa kutulutsa kwambiri kwa asidi am'mimba.
5.Postoperative gastric acid management:Pambuyo pa maopaleshoni ena, Famotidine amatha kugwiritsidwa ntchito poletsa kutulutsa kwa asidi m'mimba ndikuchepetsa chiopsezo cha zovuta zapambuyo pa opaleshoni.
Kugwiritsa ntchito
Famotidine nthawi zambiri amaperekedwa mu mawonekedwe a mapiritsi apakamwa. Odwala ayenera kumwa molingana ndi malangizo a dokotala. Mlingo ndi kuchuluka kwa ntchito kumasiyana malinga ndi momwe zilili.
Zolemba
Pogwiritsira ntchito Famotidine, odwala ayenera kudziwitsa madokotala awo ngati ali ndi mavuto ena azaumoyo kapena akumwa mankhwala ena kuti asagwirizane ndi mankhwala. Kuphatikiza apo, ngakhale Famotidine imatha kuletsa kutulutsa kwa asidi m'mimba, odwala ayenera kupita kuchipatala ngati zizindikiro zikupitilira kapena kukulirakulira.
Pomaliza, Famotidine ndiwothandiza kwambiri H2 receptor antagonist yomwe imagwiritsidwa ntchito kwambiri pochiza matenda okhudzana ndi asidi am'mimba, kuthandiza odwala kuthetsa zizindikiro ndikulimbikitsa machiritso. Iyenera kugwiritsidwa ntchito motsogozedwa ndi dokotala kuti zitsimikizire chitetezo ndi mphamvu.
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