Itracnazoazole mankhwala a tracongoazole ufa antifungal itraconazole mtengo
Mafotokozedwe Akatundu
Itraconazolendi njira yachifumu yogwira ntchito antifungual yomwe yasonyezedwa kuti igwiritse ntchito mankhwalawa ma dermal, joginal ndi zinsinsi. Pokhala odwala a Edzi ndi Edzi, itraconazole yawonetsedwa kuti ingachepetse kuchuluka kwa mizere ya cryptococcal meningitis
Cyanja
| Zinthu | Wofanana | Zotsatira |
| Atazembe | 99% isconazole | Zogwirizana |
| Mtundu | Ufa woyera | CZosintha |
| Fungo | Palibe fungo lapadera | CZosintha |
| Kukula kwa tinthu | 100% Pass 80mesh | CZosintha |
| Kutayika pakuyanika | ≤5.0% | 2.35% |
| Chotsa | ≤1.0% | Zogwirizana |
| Chitsulo cholemera | ≤10.0ppm | 7pPm |
| As | ≤2.0PPM | CZosintha |
| Pb | ≤2.0PPM | CZosintha |
| Zotsalira za Mastistide | Wosavomela | Wosavomela |
| Chiwerengero chonse cha Plate | ≤100cfu / g | Zogwirizana |
| Yisiti & nkhungu | ≤100cfu / g | Zogwirizana |
| E.coli | Wosavomela | Wosavomela |
| Nsomba monomolla | Wosavomela | Wosavomela |
| Mapeto | Kugwirizana ndi kutanthauzira | |
| Kusunga | Osungidwa m'malo ozizira & owuma, pewani kupuma mwamphamvu ndi kutentha | |
| Moyo wa alumali | Zaka 2 zikasungidwa bwino | |
Kugwira nchito
1) Itracnazoh ili ndi mawonekedwe ochulukirapo kuposa flucoconazole (koma osati wotakata ngati voriconazole kapena poschinazole). Makamaka, imagwira ntchito motsutsana ndi aspergillus omwe fluconazole sanatero.
2) Amapatsidwanso matendawa matendawa, monga a Aspergillasis, Candidiasis, ndi Cryptococcos
3) Turacnazoazole idasankhidwa posachedwapa ngati wothandizira anticancer odwala omwe ali ndi cell carcinoma.
Karata yanchito
1.Itracnazoh ndi yopanga mwamphamvu dralmazole, kukhala Antifungal wothandizira wa antiform. Makina ake antimicrobial spectrum ndi mantimicrobial makina ndi ofanana ndi kuvala bwino, koma ali ndi antibacterial a ASerrilgillus.
2.Itracnazoleh imagwira ntchito molimbika posintha mafoni am'madzi ndi antibacterial kutsutsana ndi tizilombo toyambitsa matenda apadera. Antibacterial perclerum ndi yotakata komanso yamphamvu kuposa ketoconazole, kuti ikhoza kulepheretsa ma ergeslot a cell membrane, motero amasewera antifungal.
3.Itracnazoazole ndi yoyenera mankhwalawa a dermatophytes (trichophyton, microsporom, malo otetezedwa, Carperboctums, hirpidas, hiccoccidioides Brasililienis, Sporothrix Schenckii, HARDOTMNRum, Cladosporium, blastoms dematititidis ndi mitundu yosiyanasiyana yamitundu ina ya yisiti ndi bowa. Itracnazole sangathe kuletsa kukula kwa rhizopapus ndi mucor.
Zogulitsa Zogwirizana
Fakitale yatsopanonso imaperekanso ma amino acid monga kutsatira:
Phukusi & Kutumiza
