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What Is The Difference Between TUDCA And UDCA ?

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• What is TUDCA (Taurodeoxycholic Acid ) ?

Structure: TUDCA is the abbreviation of taurodeoxycholic acid.

Source: TUDCA is a natural compound extracted from cow bile.

Mechanism of Action: TUDCA is a bile acid that increases the fluidity of bile acid in the intestine, thereby helping bile acid to be better absorbed in the intestine. In addition, TUDCA can also reduce the reabsorption of bile acid in the intestine, thereby increasing its circulation in the body.

Application: TUDCA is mainly used to treat primary biliary cholangitis (PBC) and non-alcoholic fatty liver disease+ (NAFLD).

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• What is UDCA (Ursodeoxycholic Acid) ?

Structure: UDCA is the abbreviation of ursodeoxycholic acid.

Source: UDCA is a natural compound extracted from bear bile.

Mechanism of action: UDCA is similar in structure to the body's own bile acid, so it can replace or supplement the bile acid that the body lacks. UDCA has multiple effects in the intestine, including protecting the liver, anti-inflammatory, and anti-oxidation.

Application: UDCA is mainly used to treat primary biliary cholangitis (PBC), cholesterol stones+, cirrhosis, non-alcoholic fatty liver disease (NAFLD) and other diseases.

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• What are the difference between TUDCA and UDCA in efficacy ?

Although both TUDCA and UDCA have liver-protective effects, their mechanisms may be different. TUDCA works mainly by increasing the fluidity of bile acids in the intestine, while UDCA is similar to the body's own bile acid structure and can replace or supplement the bile acid that the body lacks.

Both can be used to treat a variety of liver diseases, but they may show different effects or advantages in the treatment of certain diseases. For example, TUDCA may be more effective in the treatment of primary biliary cholangitis (PBC).

In summary, both TUDCA and UDCA are effective drugs, but there are some differences in their sources, mechanisms of action, and scope of application. If you are considering using these drugs, it is recommended to consult a doctor for more specific advice and guidance.

Although TUDCA and UDCA are both bile acids, their molecular structures are slightly different. Specifically, TUDCA is composed of a bile acid molecule and a taurine molecule bonded by an amide bond, while UDCA is just a simple bile acid molecule.

Due to the difference in molecular structure, TUDCA and UDCA also have different effects in the human body. TUDCA is more effective than UDCA in regulating renal transport, protecting the liver, and strengthening the kidneys. In addition, TUDCA also has antioxidant effects and has multiple pharmacological effects such as sedation, antianxiety, and antibacterial effects.

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TUDCA (taurodeoxycholic acid) and UDCA (ursoxycholic acid) are both types of bile acid, and are both natural substances extracted from the liver.

UDCA is the main component of bear bile. It mainly improves liver function by increasing the secretion and excretion of bile acid, thereby reducing the concentration of bile acid. Its main function is to treat cholestatic diseases such as cirrhosis, cholelithiasis, etc. In addition, it also helps to lower cholesterol levels.

TUDCA is a combination of taurine and bile acid. It can also improve liver function, but its mechanism of action is different from that of UDCA. It can enhance the liver's antioxidant capacity and protect the liver from free radical damage. In addition, it helps to improve insulin sensitivity, lower blood sugar levels, and has anti-tumor effects.

In general, UDCA and TUDCA are both good liver protectors, but their specific mechanisms of action are different and are suitable for different diseases and populations. If you need to use these two drugs, it is best to use them under the guidance of a doctor to avoid adverse reactions.

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Post time: Dec-09-2024