●What Is Ashwagandha ?
Ashwagandha, also known as Indian ginseng (Ashwagandha), is also called winter cherry, withania somnifera. Ashwagandha is recognized for its significant antioxidant capabilities and immunity-boosting properties. Additionally, ashwagandha has been used to induce sleep.
Ashwagandha contains alkaloids, steroid lactones, withanolides and iron. The alkaloids have sedative, analgesic and lowering blood pressure functions. Withanolides have anti-inflammatory effects and can inhibit the growth of cancer cells. They can also be used for chronic Inflammations such as lupus and rheumatoid arthritis, reducing leucorrhea, improving sexual function, etc., and also help in the recovery of chronic diseases. Ashwagandha is also recognized for its significant antioxidant capacity and immune-boosting properties.
According to research by scientists, ashwagandha extract has the same multiple effects as ginseng, including strengthening, stimulating, and improving human immunity. Ashwagandha extract can be processed into a drug for the treatment of male erectile dysfunction after being combined with other plants with aphrodisiac effects (such as maca, turner grass, guarana, kava root and Chinese epimedium, etc.).
●What Are The Health Benefits of Ashwagandha ?
1.Anti-Cancer
Currently, it has been confirmed that the extract ofAshwagandha has 5 mechanisms to kill cancer cells, activate the p53 tumor suppressor gene, enhance colony stimulating factor, stimulate the death pathway of cancer cells, stimulate the apoptosis pathway of cancer cells, and regulate G2-M DNA damage;
2.Neuroprotection
Ashwagandha extract can inhibit the toxic effects of scopolamine in neurons and glial cells; enhance the antioxidant activity of the brain; and reduce streptozotocin-induced oxidative damage;
In stress experiments, it was also found that Ashwagandha extract can promote the axonal growth of human neuroblastoma cells, promote the recovery and regeneration of axons and dendrites in the cerebral cortex by removing β-amyloid protein (in addition, β-amyloid protein is currently considered to be the central molecule in the onset of Alzheimer's disease);
3.Anti-Diabetes Mechanism
At present, it seems that the hypoglycemic effect of Ashwagandha is almost comparable to that of hypoglycemic drugs (glibenclamide). Ashwagandha can reduce the insulin sensitivity index of mice and reduce insulin resistance. It can promote the uptake of glucose by skeletal muscle tubules and adipocytes, thereby reducing blood sugar.
4.Antibacterial
Ashwagandha extract has a significant inhibitory effect on Gram-positive bacteria, including Staphylococcus and Enterococcus, Escherichia coli, Salmonella typhi, Proteus mirabilis, Citrobacter freundii, Pseudomonas aeruginosa, and Klebsiella pneumoniae. In addition, Ashwagandha has also been shown to have an inhibitory effect on fungi, including Aspergillus flavus, Fusarium oxysporum, and Fusarium verticillium, through spore germination and hyphae growth. So Ashwagandha currently seems to have resistance to bacteria, fungi, and protozoa.
5.Cardiovascular Protection
Ashwagandha extract can activate nuclear factor erythroid-related factor 2 (Nrf2), activate phase II detoxification enzymes, and cancel cell apoptosis caused by Nrf2. At the same time, Ashwagandha can also improve hematopoietic function. Through its preventive treatment, it can restart the body's myocardial oxidation/antioxidation and promote the balance of the two systems of cell apoptosis/anti-cell apoptosis. It has also been found that ashwagandha can also regulate the cardiotoxicity caused by doxorubicin.
6.Relieve Stress
Ashwagandha can relieve T cells and upregulate Th1 cytokines caused by stress. In human clinical trials, it has been confirmed that it can reduce cortisol hormones without any side effects. A multi-herbal complex called EuMil (including ashwagandha) can improve monoamine transmitters in the brain. It can also relieve glucose intolerance and male sexual dysfunction caused by stress.
7.Anti-Inflammatory
It is currently believed that ashwagandha root extract has a direct inhibitory effect on inflammatory markers including tumor necrosis factor (TNF-α), nitric oxide (NO), reactive oxygen species (ROS), nuclear factor (NFк-b), and interleukin (IL-8&1β). At the same time, it can weaken the extracellular regulated kinase ERK-12, p38 protein phosphorylation induced by phorbol myristate acetate (PMA), and C-Jun amino-terminal kinase.
8.Improve Male/Female Sexual Function
A paper published in "BioMed research international" (IF3.411/Q3) in 2015 studied the effects of ashwagandha on female sexual function. The conclusion supports that ashwagandha extract can be used to treat female sexual dysfunction, which is safe and has no side effects.
Ashwagandha can increase the concentration and activity of male sperm, increase testosterone, luteinizing hormone, follicle-stimulating hormone, and has a positive effect on various oxidative markers and antioxidant markers.
●NEWGREEN Supply Ashwagandha Extract Powder/Capsules/ Gummies
Post time: Nov-08-2024
