Newgreen Supply High Quality Shiitake Mushroom Extract LentinanPowder
Product Description
Lentinan (LNT) is an effective active component extracted from the fruiting body of high-quality lentinan. Lentinan is the main active component of Lentinan and a host defense potentiator (HDP). Clinical and pharmacological studies show that Lentinan is a host defense potentiator. Lentinan has anti-virus, anti-tumor, regulating immune function and stimulating interferon formation.
Lentinan is grayish white or light brown powder, mostly acidic polysaccharide, soluble in water, dilute alkali, especially soluble in hot water, insoluble in ethanol, acetone, ethyl acetate, ether and other organic solvents, its aqueous solution is transparent and viscous
COA：
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Product Name: |
Lentinan |
Test Date: |
2024-07-14 |
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Batch No.: |
NG24071301 |
Manufacture Date: |
2024-07-13 |
|
Quantity: |
2400kg |
Expiration Date: |
2026-07-12 |
| ITEMS | STANDARD | RESULTS |
| Appearance | Brown Powder | Conform |
| Odor | Characteristic | Conform |
| Taste | Characteristic | Conform |
| Assay | ≥30.0% | 30.6% |
| Ash Content | ≤0.2％ | 0.15% |
| Heavy Metals | ≤10ppm | Conform |
| As | ≤0.2ppm | ＜0.2 ppm |
| Pb | ≤0.2ppm | ＜0.2 ppm |
| Cd | ≤0.1ppm | ＜0.1 ppm |
| Hg | ≤0.1ppm | ＜0.1 ppm |
| Total Plate Count | ≤1,000 CFU/g | ＜150 CFU/g |
| Mold & Yeast | ≤50 CFU/g | ＜10 CFU/g |
| E. Coll | ≤10 MPN/g | ＜10 MPN/g |
| Salmonella | Negative | Not Detected |
| Staphylococcus Aureus | Negative | Not Detected |
| Conclusion | Conform to the specification of the requirement. | |
| Storage | Store in a cool, dry and ventilated place place. | |
| Shelf Life | Two years if sealed and store away from direct sun light and moisture. | |
Function:
1. Antitumor activity of lentinan
Lentinan has anti-tumor effect, it has no toxic side effects of chemotherapy drugs. Lentinan into the antibody induces the production of a kind of immunoactive cytokine. Under the combined action of these cytokines, the immune system of the body is enhanced, and it plays a defense and killing role on tumor cells.
2. Immune regulation of lentinan
The immunomodulatory effect of lentinan is the important basis of its biological activity. Lentinan is a typical T cell activator, promotes the production of interleukin, and also promotes the function of mononuclear macrophages, and is considered as a special immune enhancer.
3. Antiviral activity of lentinan
Shiitake mushrooms contain a double-stranded ribonucleic acid, which can stimulate human reticular cells and white blood cells to release interferon, which has antiviral effects. The mushroom mycelium extract can inhibit the absorption of herpes virus by cells, so as to prevent and cure various diseases caused by herpes simplex virus and cytomegalovirus. Some scholars have found that sulfated lentinus edodes have anti-AIDS virus (HIV) activity and can interfere with the adsorption and invasion of retroviruses and other viruses.
4. Anti-infection effect of lentinan
Lentinan can improve the function of macrophages. Lentinus edodes can inhibit Abelson virus, adenovirus type 12 and influenza virus infection, and is a good drug for treating various hepatitis, especially chronic migratory hepatitis.
Application:
1. Application of lentinan in the field of medicine
Lentinan has good curative effect in the treatment of gastric cancer, colon cancer and lung cancer. As an immunoadjuvant drug, lentinan is mainly used to inhibit the occurrence, development and metastasis of tumors, improve the sensitivity of tumors to chemotherapy drugs, improve the physical condition of patients, and extend their life.
The combination of lentinan and chemotherapeutic agents has the effect of attenuating toxicity and enhancing efficacy. Chemotherapy drugs have poor selectivity to kill tumor cells, and can also kill normal cells, resulting in toxic side effects, resulting in chemotherapy can not be carried out on time and in quantity; Due to the insufficient dose of chemotherapy, it often causes drug resistance of tumor cells and becomes a refractory cancer, which affects the curative effect. Taking lentinan during chemotherapy can enhance the efficacy of chemotherapy and reduce the toxicity of chemotherapy. At the same time, the incidence of leukopenia, gastrointestinal toxicity, liver function damage and vomiting were significantly reduced during chemotherapy. This fully shows that the combination of lentinan and chemotherapy can enhance the efficacy, reduce the toxicity, and enhance the immune function of patients.
Lentinan combined with other drugs in the treatment of chronic hepatitis B can improve the negative effect of hepatitis B virus markers and reduce the side effects of antiviral drugs. In addition, lentinan can be used to treat tuberculosis infection.
2. The application of Lentinan in the field of health food
Lentinan is a kind of special bioactive substance, it is a kind of biological response enhancer and modulator, it can enhance humoral immunity and cellular immunity. The antiviral mechanism of lentinan may be that it can improve the immunity of infected cells, enhance the stability of cell membrane, inhibit cyopathies, and promote cell repair. At the same time, lentinan also has anti-retroviral activity. Therefore, lentinan can be used as a health food raw material to enhance immunity
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