Newgreen Supply High Quality Artemisia Annua Extract 98% Artemisinin Powder
Product Description
Artemisinin is a pharmaceutical ingredient extracted from the Artemisia annua plant, also known as dihydroartemisinin. It is an effective antimalarial drug and is widely used to treat malaria. Artemisinin has a strong killing effect on Plasmodium, especially on the female gametocytes and schizonts of Plasmodium. Artemisinin and its derivatives have become one of the important drugs for the treatment of malaria and are of great significance for the treatment of malaria.
In recent years, with the deepening of research, artemisinin has also been found to have other pharmacological effects, such as anti-tumor, treatment of pulmonary hypertension, anti-diabetes, embryonic toxicity, anti-fungal, immune regulation, antiviral, anti-inflammatory, anti-pulmonary fibrosis, antibacterial, cardiovascular and other pharmacological effects.
Artemisinin is a colorless acicular crystal, soluble in chloroform, acetone, ethyl acetate and benzene, soluble in ethanol, ether, slightly soluble in cold petroleum ether, almost insoluble in water. Because of its special peroxy groups, it is thermally unstable and susceptible to decomposition by humidity, heat and reducing substances.
COA：
|
Product Name: |
Artemisinin |
Test Date: |
2024-05-16 |
|
Batch No.: |
NG24070501 |
Manufacture Date: |
2024-05-15 |
|
Quantity: |
300kg |
Expiration Date: |
2026-05-14 |
| ITEMS | STANDARD | RESULTS |
| Appearance | White Powder | Conform |
| Odor | Characteristic | Conform |
| Taste | Characteristic | Conform |
| Assay | ≥98.0% | 98.89% |
| Ash Content | ≤0.2％ | 0.15% |
| Heavy Metals | ≤10ppm | Conform |
| As | ≤0.2ppm | ＜0.2 ppm |
| Pb | ≤0.2ppm | ＜0.2 ppm |
| Cd | ≤0.1ppm | ＜0.1 ppm |
| Hg | ≤0.1ppm | ＜0.1 ppm |
| Total Plate Count | ≤1,000 CFU/g | ＜150 CFU/g |
| Mold & Yeast | ≤50 CFU/g | ＜10 CFU/g |
| E. Coll | ≤10 MPN/g | ＜10 MPN/g |
| Salmonella | Negative | Not Detected |
| Staphylococcus Aureus | Negative | Not Detected |
| Conclusion | Conform to the specification of the requirement. | |
| Storage | Store in a cool, dry and ventilated place place. | |
| Shelf Life | Two years if sealed and store away from direct sun light and moisture. | |
Function:
Artemisinin is an effective antimalarial drug that:
1. Kill Plasmodium: Artemisinin has a strong killing effect on Plasmodium, especially on the female gametocytes and schizonts of Plasmodium.
2. Quickly relieve symptoms: Artemisinin can quickly relieve symptoms such as fever, chills, headaches and other symptoms in malaria patients. It is a fast and effective anti-malarial drug.
3. Prevent the recurrence of malaria: Artemisinin can also be used to prevent the recurrence of malaria, especially in some areas with high malaria incidence. The use of artemisinin can help prevent the spread and recurrence of malaria.
Application:
Artemisinin is the most effective drug to treat malaria resistance, and artemisinin-based combination therapy is also the most effective and important means to treat malaria at present. However, with the deepening of research in recent years, more and more other effects of artemisinin have been discovered and applied, such as anti-tumor, treatment of pulmonary hypertension, anti-diabetes, embryonic toxicity, antifungal, immune regulation and so on.
1. Anti-malaria
Malaria is an insect-borne infectious disease, an infectious disease caused by the bite of the parasite infected by the parasite, which can cause liver and spleen enlargement after multiple attacks for a long time, and accompanied by anemia and other symptoms. Artemisinin has been instrumental in achieving a certain level of treatment for malaria.
2. Anti-tumor
In vitro experiments show that a certain dose of artemisinin can induce apoptosis of liver cancer cells, breast cancer cells, cervical cancer cells and other cancer cells, and significantly inhibit the growth of cancer cells.
3. Treatment of pulmonary hypertension
Pulmonary hypertension (PAH) is a pathophysiological condition characterized by pulmonary artery remodeling and elevated pulmonary artery pressure to a certain limit, which can be a complication or syndrome. Artemisinin is used to treat pulmonary hypertension: it reduces pulmonary artery pressure and improves symptoms in patients with PAH by dilating blood vessels. Artemisinin has anti-inflammatory effect, artemisinin and its kernel can inhibit a variety of inflammatory factors, and can inhibit the production of nitric oxide by inflammatory mediators. Artemisinin can inhibit the proliferation of vascular endothelial cells and vascular smooth muscle cells, which plays an important role in the treatment of PAH. Artemisinin can inhibit the activity of matrix metalloproteinases and thus inhibit pulmonary vascular remodeling. Artemisinin can inhibit the expression of PAH related cytokines, and further enhance the anti-vascular remodeling effect of artemisinin.
4. Immune regulation
It was found that the dose of artemisinin and its derivatives could inhibit T lymphocyte mitogen well without causing cytotoxicity, thus inducing the proliferation of mouse spleen lymphocytes.
5. Anti-fungal
The antifungal action of artemisinin also makes artemisinin exhibit certain antibacterial activity. The study confirmed that artemisinin residue powder and water decoction had strong antibacterial action against Bacillus anthracis, Staphylococcus epidermidis, Coccus catarrhus and Bacillus diphtheriae, and also had certain antibacterial action against Bacillus tuberculosis, Bacillus aeruginosa, Staphylococcus aureus and Bacillus dysenteriae.
6. Anti-diabetes
Artemisinin may also save people with diabetes. Scientists from the CeMM Center for Molecular Medicine at the Austrian Academy of Sciences and other institutions found that artemisinin can make glucagon-producing alpha cells "transform" into insulin-producing beta cells. Artemisinin binds to a protein called gephyrin. Gephyrin activates the GABA receptor, the main switch for cell signaling. Subsequently, numerous biochemical reactions change, leading to the production of insulin.
7. Treatment of polycystic ovary syndrome
The study found that artemisinin derivatives can treat PCOS and elucidate the related mechanism, providing a new idea for clinical treatment of PCOS and androgen elevation-related diseases.
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