Newgreen Supply High Quality 101 Herba Clinopodii Extract Powder
Product Description
Herba Clinopodii extract is derived from the dried aboveground part of Clinopodiumpolycephalum(Vaniot) C.y.weethsuan or Clinopodiumchinensis(Benth.) o.Kotze of the labiaceae family.
The extract contains flavonoids, saponins, amino acids, coumarin and so on. The main flavonoids are balsamin, hesperidin, isosakurin and apigenin. The saponins include ursolic acid, saponin A and so on. The physiological active ingredient is triterpenoid saponin.
COA
ITEMS | STANDARD | RESULTS |
Appearance | Brown Powder | Conform |
Odor | Characteristic | Conform |
Taste | Characteristic | Conform |
Extract Ratio | 10:1 | Conform |
Ash Content | ≤0.2% | 0.15% |
Heavy Metals | ≤10ppm | Conform |
As | ≤0.2ppm | <0.2 ppm |
Pb | ≤0.2ppm | <0.2 ppm |
Cd | ≤0.1ppm | <0.1 ppm |
Hg | ≤0.1ppm | <0.1 ppm |
Total Plate Count | ≤1,000 CFU/g | <150 CFU/g |
Mold & Yeast | ≤50 CFU/g | <10 CFU/g |
E. Coll | ≤10 MPN/g | <10 MPN/g |
Salmonella | Negative | Not Detected |
Staphylococcus Aureus | Negative | Not Detected |
Conclusion | Conform to the specification of the requirement. | |
Storage | Store in a cool, dry and ventilated place place. | |
Shelf Life | Two years if sealed and store away from direct sun light and moisture. |
Function:
The extract has the following pharmacological effects
1. Hypoglycemic effect
The possible mechanism of the ethanol extract from the Herba Clinopodii can be used in the treatment of diabetes, which is to increase liver glycogen synthesis, reduce liver glycogen decomposition, provide anti-lipid peroxidation ability of the body, and thus reduce the damage of islet cells. The extract of the effective part of the Herba Clinopodii can significantly reduce the content of blood glucose and serum cholesterol in streptozotocin induced diabetes mellitus, improve the islet disease, inhibit α-glucosidase and protect vascular endothelial cells, and can be used to prepare drugs for the treatment of diabetes mellitus.
2. Antibacterial effect
Herba Clinopodii extract had the strongest inhibitory effect on staphylococcus aureus, followed by Escherichia coli, pseudomonas aeruginosa and Candida albicans, but had no inhibitory effect on Bacillus subtilis, Aspergillus Niger, penicillium and saccharomyces cerevisiae.
3. Constriction of blood vessels
The Herba Clinopodii alcohol extract can improve the contractile force of thoracic aorta, pulmonary aorta, uterine artery, renal artery, portal vein and other blood vessels, among which the uterine artery has the strongest effect. Compared with norepinephrine, the effect is slow, mild and lasting.
4. Hemostatic effect
The Herba Clinopodii alcohol extract can inhibit the increase of skin capillary permeability caused by histamine phosphate, and can maintain blood vessel wall. It is also suitable for hemorrhagic diseases caused by abnormal blood vessel wall. In addition, the total saponins of broken Herba Clinopodii can significantly promote platelet aggregation in vivo and in vitro. The aggregation intensity is large, the average aggregation rate is fast, the deaggregation is slow, and the platelet adhesion rate is significantly increased, which may be another important factor for its hemostatic effect.
5. Uterine contractions
The total glycosides of Herba Clinopodii can improve the contractility of uterine artery and significantly increase uterine weight, while the content of estrogen (estradiol) is increased, and the level of progesterone (progesterone) is not significantly affected, indicating that this product may affect the pituitary-gonadal axis endocrine system.
Application:
Clinically, the preparation of Herba Clinopodii is widely used in the treatment of various bleeding, simple purpura, primary thrombocytopenic purpura and other diseases. Its curative effect is accurate, high safety, is commonly used in clinical gynecological hemostatic medicine.
1. Gynecological bleeding drugs: Herba Clinopodii breaking preparations are ideal drugs for the treatment of functional uterine bleeding, with high efficacy, fast onset time, short treatment days, and no toxicity or serious side effects.
2. Oral hemorrhagic diseases: Herba Clinopodii disruption has a certain hemostatic effect in the treatment of oral hemorrhagic diseases, especially for non-inflammatory bleeding.
3. Other diseases: Broken Herba Clinopodii can treat suppurative paronychia, and is also used to treat skin furuncle abscess, irregular menstruation of women and various bleeding disorders.