Newgreen Supply Camptotheca Acuminata Extract 99% Camptothecin Powder
Product Description
Camptothecin is an alkaloid naturally occurring in plants of the Camptotheca and has anti-tumor activity. It has been found to have inhibitory effects on a variety of cancer types, especially solid tumors such as colorectal cancer and ovarian cancer. Camptothecin blocks DNA replication and transcription by inhibiting the activity of DNA topoisomerase I, thereby leading to cancer cell apoptosis.
Camptothecin and its derivatives have become clinically important anticancer drugs, such as the Camptothecin derivative carboplatin and the Camptothecin derivative Camptothecin base. They are widely used to treat a variety of cancers, including ovarian, breast, prostate, and others.
COA
| ITEMS | STANDARD | RESULTS |
| Appearance | White Powder | Conform |
| Odor | Characteristic | Conform |
| Taste | Characteristic | Conform |
| Assay（Camptothecin） | ≥98.0% | 99.89% |
| Ash Content | ≤0.2％ | 0.15% |
| Heavy Metals | ≤10ppm | Conform |
| As | ≤0.2ppm | ＜0.2 ppm |
| Pb | ≤0.2ppm | ＜0.2 ppm |
| Cd | ≤0.1ppm | ＜0.1 ppm |
| Hg | ≤0.1ppm | ＜0.1 ppm |
| Total Plate Count | ≤1,000 CFU/g | ＜150 CFU/g |
| Mold & Yeast | ≤50 CFU/g | ＜10 CFU/g |
| E. Coll | ≤10 MPN/g | ＜10 MPN/g |
| Salmonella | Negative | Not Detected |
| Staphylococcus Aureus | Negative | Not Detected |
| Conclusion | Conform to the specification of the requirement. | |
| Storage | Store in a cool, dry and ventilated place place. | |
| Shelf Life | Two years if sealed and store away from direct sun light and moisture. | |
Function
Camptothecin’s main functions include:
1. Anti-tumor effect: Camptothecin blocks DNA replication and transcription by inhibiting the activity of DNA topoisomerase I, thereby causing cancer cell apoptosis. This makes Camptothecin and its derivatives clinically important anti-cancer drugs for the treatment of various cancers, such as ovarian cancer, breast cancer, prostate cancer, etc.
2. Anti-inflammatory effect: Some studies have shown that Camptothecin may have anti-inflammatory effects and may have a certain impact on some inflammatory diseases.
It should be noted that Camptothecin has strong toxic side effects, so it needs to be used under the guidance of a professional doctor. If you have more questions about the functions of Camptothecin, it is recommended to consult a professional doctor or pharmacist for more detailed and accurate information.
Application
Camptothecin and its derivatives are widely used in clinical treatment of various cancers, including but not limited to ovarian cancer, breast cancer, prostate cancer, etc. They are often used as part of chemotherapy drugs, either as single agents or in combination therapy. Camptothecin blocks DNA replication and transcription by inhibiting the activity of DNA topoisomerase I, thereby causing cancer cell apoptosis.
The application scenario of Camptothecin is mainly for solid tumors, especially for some patients with advanced cancer or patients who are ineffective in other treatments. However, the specific usage needs to be determined based on the patient's condition, doctor's advice and clinical reality.
Package & Delivery
