Newgreen Best Selling S-adenosyl methionine 99% Supplement S-adenosyl methionine Powder with Best Price
Product Description
S-Adenosyl Methionine (SAM or SAMe) is a compound produced naturally in the body, mainly synthesized from adenosine triphosphate (ATP) and methionine. SAMe plays an important role in many biochemical reactions, especially in methylation reactions.
Main Features
1. Methyl donor: SAMe is an important methyl donor and participates in the methylation process of DNA, RNA and protein. These methylation reactions are crucial for gene expression, cell signaling and metabolic regulation.
2. Synthesis of bioactive molecules: SAMe is involved in the synthesis of a variety of bioactive molecules, including neurotransmitters (such as dopamine and norepinephrine) and phospholipids (such as phosphatidylcholine).
3. Antioxidant Effect: SAMe has antioxidant properties that can help protect cells from damage caused by oxidative stress.
In conclusion, S-adenosylmethionine is an important biomolecule with multiple biological functions and potential clinical applications, but it should be used with caution and in accordance with professional advice.
COA
Certificate of Analysis
| Items | Specifications | Results | |
| Appearance | White to off-white powder | Complies | |
| Odor | Infrared | Conforms to the reference spectrum | Complies |
| HPLC | The retention time of the major peak corresponds to the reference sample | Complies | |
| Water content(K.F) | ≤ 3.0% | 1.12% | |
| Sulphated Ash | ≤ 0.5% | Complies | |
| PH(5% aqueous solution) | 1.0-2.0 | 1.2% | |
| S,S-Isomer(HPLC) | ≥ 75.0% | 82.16% | |
| SAM-e ION(HPLC) | 49.5%-54.7% | 52.0% | |
| P-Toluenesulfonic Acid | 21.0%-24.0% | 22.6% | |
| Content of Sulfate(SO4)(HPLC) | 23.5%-26.5% | 25.5% | |
| Assay（S-Adenosyl-L-methionine Disulfate Tosylate） | 95.0%-102% | 99.9% | |
| Related substances(HPLC) | |||
| S-ADENOSYL-L-HOMOCYSTEINE | ≤ 1.0% | 0.1% | |
| ADENINE | ≤ 1.0% | 0.2% | |
| METHYLTHIOADENOSINE | ≤ 1.5% | 0.1% | |
| ADENOSINE | ≤ 1.0% | 0.1% | |
| TOTAL IMPURITIES | ≤3.5% | 0.8% | |
| Bulk Density | > 0.5g/ml | Complies | |
| Heavy Metal | < 10ppm | Complies | |
| Pb | < 3ppm | Complies | |
| As | <2ppm | Complies | |
| Cd | <1ppm | Complies | |
| Hg | <0.1ppm | Complies | |
| Microbiology | |||
| Total Plate Count | ≤ 1000cfu/g | <1000cfu/g | |
| Yeast & Moulds | ≤ 100cfu/g | <100cfu/g | |
| E.Coli. | Negative | Negative | |
| Salmonella | Negative | Negative | |
| Conclusion
|
Complies with USP37 | ||
| Storage | Store in 2-8℃ place not freeze,keep away from strong light and heat | ||
| Shelf life | 2 years when properly stored | ||
Function
S-Adenosine Methionine (SAMe) is a naturally occurring compound in the body, primarily composed of adenosine and methionine. It plays an important role in many biological processes. Here are some of the main functions of SAMe:
1. Methyl donor: SAMe is an important methyl donor and participates in methylation reactions in the body. These reactions are essential for the modification of DNA, RNA and proteins, affecting gene expression and cell function.
2. Promote neurotransmitter synthesis: SAMe helps synthesize a variety of neurotransmitters in the nervous system, such as serotonin and dopamine, which are closely related to mood regulation and mental health.
3. Antidepressant Effects: Some studies have shown that SAMe may have a positive effect on depression as a complementary therapy, helping to improve mood and reduce depressive symptoms.
4. Liver Health: SAMe plays an important role in the liver, participating in the liver's detoxification process and fat metabolism, helping to protect liver cells and promote liver health.
5. Joint Health: SAMe is used to relieve joint inflammation and pain, and may improve joint function by promoting the synthesis and repair of cartilage.
6. Antioxidant Effect: SAMe has certain antioxidant properties that help protect cells from damage caused by oxidative stress.
Overall, S-adenosylmethionine plays an important role in a variety of physiological processes, especially in mental health, liver function, and joint health. Although its use as a supplement is becoming more common, it is best to consult a doctor or professional before using it.
Application
S-Adenosyl Methionine (SAMe) is widely used in many fields, mainly including the following aspects:
1. Depression and mood disorders
SAMe has been studied as a supplement to aid in the treatment of depression. Research suggests that SAMe may improve mood by increasing levels of neurotransmitters such as dopamine and norepinephrine. Some clinical trials have shown that SAMe may be as effective as traditional antidepressant medications in relieving symptoms of depression.
2. Joint Health
SAMe is used to treat osteoarthritis and other joint conditions. It may help patients by reducing joint pain and improving function. Some studies suggest that SAMe is similarly effective as nonsteroidal anti-inflammatory drugs (NSAIDs) in relieving joint inflammation and pain, but with fewer side effects.
3. Liver Health
SAMe has also shown potential in the treatment of liver diseases. It is used to treat conditions such as liver steatosis, hepatitis, and cirrhosis. SAMe may work by promoting the regeneration of liver cells and improving liver function.
4. Nervous system health
SAMe has also received attention in research on neurodegenerative diseases such as Alzheimer’s and Parkinson’s. It may support the health of the nervous system by improving the synthesis of neurotransmitters and reducing oxidative stress.
5. Cardiovascular Health
Some research suggests that SAMe may benefit cardiovascular health, possibly by lowering homocysteine levels (high homocysteine is associated with cardiovascular disease risk).
6. Other Applications
SAMe is also being studied for other health issues, such as fibromyalgia, chronic fatigue syndrome, and certain types of cancer. Although research into these applications is still ongoing, preliminary results show some promise.
Notes
Before using SAMe as a supplement, it is recommended to consult a doctor, especially for people with specific health problems or who are taking other medications. SAMe may interact with certain medications, such as antidepressants, so professional guidance is important.
In conclusion, S-adenosylmethionine has potential applications in multiple health areas, but more research is needed to further confirm its effectiveness and safety.
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