Itraconazole Pharmaceutical Grade Traconazole Powder Antifungal Itraconazole Price
Product Description
Itraconazole is an orally-active triazole antifungal indicated for use in the treatment of dermal, vaginal and systemic mycoses. In immunocompromised and AIDS patients, itraconazole has been shown to significantly reduce the incidence of relapses of cryptococcal meningitis
COA
|
ITEMS |
STANDARD |
TEST RESULT |
| Assay | 99% Itraconazole | Conforms |
| Color | White powder | Conforms |
| Odor | No special smell | Conforms |
| Particle size | 100% pass 80mesh | Conforms |
| Loss on drying | ≤5.0% | 2.35% |
| Residue | ≤1.0% | Conforms |
| Heavy metal | ≤10.0ppm | 7ppm |
| As | ≤2.0ppm | Conforms |
| Pb | ≤2.0ppm | Conforms |
| Pesticide residue | Negative | Negative |
| Total plate count | ≤100cfu/g | Conforms |
| Yeast & Mold | ≤100cfu/g | Conforms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
|
Conclusion |
Conform with Specification |
|
|
Storage |
Stored in Cool & Dry Place, Keep Away From Strong Light And Heat |
|
|
Shelf life |
2 years when properly stored |
|
Function
1) Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus which fluconazole is not.
2) It is also prescribed for systemic infections, such as aspergillosis, candidiasis, and cryptococcosis
3) Itraconazole has also recently been explored as an anticancer agent for patients with basal cell carcinoma.
Application
1.Itraconazole is an artificially synthetic clotrimazole, being a broad-spectrum synthetic antifungal agent. Its antimicrobial spectrum and antimicrobial mechanism is similar to clotrimazole, but has strong antibacterial activity against Aspergillus.
2.Itraconazole exerts its anti-fungal effect through changing the fungal cell membrane permeability with antibacterial activity against superficial and deep fungal pathogens. Its antibacterial spectrum is broader and stronger than ketoconazole, being able to inhibit the ergosterol synthesis of fungal cell membrane, thus playing the antifungal effect.
3.Itraconazole is suitable for the treatment of Dermatophytes (Trichophyton, Microsporum, Flocculent Epidermophyton), Yeast [Cryptococcus neoformans, Pityrosporum, Candida (including Candida albicans, Candida glabrata and candida krusei)], Aspergillus, Histoplasma, Paracoccidioides brasiliensis, Sporothrix schenckii, Hormodendrum, Cladosporium, Blastomyces dermatitidis and various kinds of other types of yeasts and fungi. Itraconazole is not able to inhibit the growth of Rhizopus and Mucor.
Related products
Newgreen factory also supplies Amino acids as following:
Package & Delivery
