• Gịnị BụCaffeic acid ?
Caffeic acid bụ ogige phenolic nwere nnukwu antioxidant na ihe mgbochi mkpali, nke dị na nri na osisi dị iche iche. Uru ahụike ya nwere ike na ngwa na nri, ihe ịchọ mma, na mgbakwunye na-eme ka ọ bụrụ ihe dị mkpa na nyocha nri na ahụike.
Enwere ike imepụta caffeic acid site na osisi ma ọ bụ kemịkalụ. Ndị a bụ ụzọ abụọ a na-ahụkarị maka imepụta caffeic acid:
Mwepụta sitere na isi mmalite:
A na-ahụ caffeic acid n'ụdị osisi dị iche iche, dị ka kọfị, apụl, na artichokes. Ụzọ kachasị esi enweta caffeic acid bụ iji wepụ ya na isi mmalite ndị a. Usoro mmịpụta ahụ gụnyere iji ihe mgbaze dị ka methanol ma ọ bụ ethanol kewapụ caffeic acid na ihe ọkụkụ ndị ọzọ. A na-asachapụ ihe ndị ahụ iji nweta caffeic acid.
Ngwakọta kemịkalụ:
A nwekwara ike iji kemịkalụ mepụta caffeic acid site na phenol ma ọ bụ phenols dochie anya. Njikọ ahụ gụnyere imeghachi omume phenol ma ọ bụ phenols dochie ya na carbon monoxide na palladium catalyst iji mepụta etiti hydroxypropyl ketone, bụ nke a na-emeghachi ya ọzọ na ihe na-eme ọla kọpa iji mepụta caffeic acid.
Usoro njikọ kemịkalụ a nwere ike ịmepụta caffeic acid n'ọtụtụ buru ibu ma nwee ike imeziwanye mkpụrụ na ịdị ọcha nke ngwaahịa ahụ. Otú ọ dị, usoro mmịpụta sitere na isi mmalite dị mma na gburugburu ebe obibi ma na-emepụta ngwaahịa ndị ọzọ.
• Njirimara anụ ahụ na kemịkalụ nkeCaffeic acid
1. Njirimara anụ ahụ
Ụdị molekụla:C₉H₈O₄
Ibu Molecular:Ihe dị ka 180.16 g/mol
Ọdịdị:Caffeic acid na-apụtakarị dị ka ntụ ntụ na-acha odo odo ruo aja aja.
Solubility:Ọ na-agbaze na mmiri, ethanol, na methanol, mana ọ na-esighi ike na ihe mgbaze na-abụghị polar dị ka hexane.
Ebe mgbaze:Ebe mgbaze nke caffeic acid dị gburugburu 100-105 Celsius (212-221 Celsius F).
2. Njirimara Chemical
Acidity:Caffeic acid bụ acid na-adịghị ike, yana uru pKa dị ihe dịka 4.5, na-egosi na ọ nwere ike inye protons na ngwọta.
Mmeghachi omume:Ọ nwere ike nweta mmeghachi omume kemịkalụ dị iche iche, gụnyere:
Oxidation:Caffeic acid nwere ike oxidized ka ọ bụrụ ogige ndị ọzọ, dị ka quinones.
Esterification:Ọ nwere ike meghachi omume na mmanya na-egbu egbu iji mepụta esters.
Polymerization:N'okpuru ọnọdụ ụfọdụ, caffeic acid nwere ike ime ka ogidi phenolic buru ibu.
3. Njirimara Spectroscopic
Ntinye UV-Vis:Caffeic acid na-egosiputa nnabata siri ike na mpaghara UV, nke enwere ike iji maka ọnụọgụ ya n'ụdị dị iche iche.
Spectrum infrared (IR):Ụdịdị dị iche iche nke IR na-egosi ọnụ ọgụgụ dị elu nke kwekọrọ na hydroxyl (-OH) na carbonyl (C=O).
• Wepụ isi mmalite nkeCaffeic acid
Enwere ike ị nweta caffeic acid site na isi mmalite dị iche iche, ọkachasị osisi.
Agwa kọfị:
Otu n'ime isi mmalite nke caffeic acid, karịsịa na kọfị a ṅara n'ọkụ.
Mkpụrụ osisi:
Apụl: Nwere caffeic acid na akpụkpọ na anụ ahụ.
Pears: Mkpụrụ ọzọ nwere nnukwu caffeic acid.
Tomato: dị ka blueberries na strawberries.
Akwụkwọ nri:
Karọt: Nwere caffeic acid, karịsịa na akpụkpọ ahụ.
Nduku: Ọkachasị na akpụkpọ ahụ na bee.
Osisi na ose:
Thyme: Nwere nnukwu ọ̀tụ̀tụ̀ caffeic acid.
Sage: ogwu ọzọ bara ụba na caffeic acid.
Mkpụrụ zuru ezu:
Oats: Nwere caffeic acid, na-enye aka na uru ahụike ya.
Isi mmalite ndị ọzọ:
Mmanya uhie: Nwere caffeic acid n'ihi ọnụnọ nke ogige phenolic na mkpụrụ vaịn.
Mmanụ aṅụ: Ụfọdụ ụdị mmanụ aṅụ nwekwara caffeic acid.
• Gịnị bụ uru nkeCaffeic acid ?
1. Njirimara Antioxidant
◊ Nchọgharị radical efu:Caffeic acid na-enyere aka ịkwụsị radicals free, nke nwere ike ibelata nrụgide oxidative ma belata ohere nke ọrịa na-adịghị ala ala.
2. Mmetụta mgbochi mkpali
◊ Mbelata mbufụt:Ọ nwere ike inye aka belata mbufụt na ahụ, nke jikọtara ya na ọnọdụ dị iche iche dị ka ogbu na nkwonkwo, ọrịa obi, na ụfọdụ ọrịa cancer.
3. Mmetụta mgbochi ọrịa cancer nwere ike ime
◊ Mgbochi nke uto mkpụrụ ndụ kansa:Nnyocha ụfọdụ na-egosi na caffeic acid nwere ike igbochi mmụba nke mkpụrụ ndụ kansa ma mee ka apoptosis (ọnwụ cell emebere) n'ụdị ọrịa cancer ụfọdụ.
4. Nkwado maka ahụike obi obi
◊ Nlekọta cholesterol:Caffeic acid nwere ike inye aka belata ọkwa LDL cholesterol ma melite ahụike obi n'ozuzu ya.
◊ Iwu Ọbara Ọbara:Ọ nwere ike itinye aka na nhazi nke ọbara mgbali elu, na-akwalite ịrụ ọrụ nke obi ka mma.
5. Mmetụta Neuroprotective
◊ Ahụ Ike ọgụgụ isi:A mụọla caffeic acid maka ikike ọ nwere ichebe megide ọrịa neurodegenerative, dị ka Alzheimer na Parkinson, site na ibelata nrụgide oxidative na ụbụrụ.
6. Ahụ Ike Skin
◊ Njirimara mgbochi ịka nká:N'ihi mmetụta antioxidant na mgbochi mkpali, caffeic acid na-etinyekarị na ngwaahịa nlekọta anụ ahụ iji nyere aka chebe akpụkpọ ahụ pụọ na mmebi ma kwalite ọdịdị ntorobịa.
7. Ahụ Ike Digestive
◊ Ahụ ike eriri afọ:Caffeic acid nwere ike ịkwado ahụike eriri afọ site n'ịkwalite uto nke nje bacteria bara uru na ibelata mbufụt na tract digestive.
• Gịnị bụ ngwa nkeCaffeic acid ?
Caffeic acid nwere ngwa dị iche iche n'ofe ubi dị iche iche, gụnyere nri, ọgwụ, ihe ịchọ mma, na ọrụ ugbo. Nke a bụ ụfọdụ ngwa ngwa:
1. Ụlọ ọrụ nri
◊ Ihe nchekwa eke: A na-eji caffeic acid mee ihe dị ka antioxidant eke iji gbasaa ndụ ngwaahịa nri site na igbochi oxidation.
◊ Ihe na-atọ ụtọ: Ọ nwere ike ịkwalite profaịlụ ụtọ nke ụfọdụ nri na ihe ọṅụṅụ, karịsịa na kọfị na tii.
2. Ọgwụ ọgwụ
◊ Nutraceuticals: Caffeic acid na-etinye na mgbakwunye nri maka uru ahụike ọ nwere, dị ka antioxidant na mmetụta mgbochi mkpali.
◊ Nchọpụta ọgwụgwọ: A na-amụ ya maka ọrụ ọ nwere n'igbochi na ịgwọ ọrịa dị iche iche, gụnyere ọrịa kansa na ọrịa neurodegenerative.
3. Ihe ịchọ mma na nlekọta anụ ahụ
◊ Ngwaahịa na-egbochi ịka nká: N'ihi njirimara antioxidant ya, a na-etinyekarị caffeic acid n'ime usoro nlekọta anụ ahụ iji chebe akpụkpọ ahụ pụọ na mmebi oxidative ma kwalite ọdịdị ntorobịa.
◊ Usoro mgbochi mkpali: A na-eji ya na ngwaahịa iji belata mbufụt na mgbakasị ahụ.
4. Agriculture
◊ Onye na-akwalite uto ihe ọkụkụ: Enwere ike iji caffeic acid dị ka onye na-ahụ maka uto okike iji kwalite uto osisi na iguzogide nrụgide.
◊ Mmepe pesticide: Nchọpụta na-aga n'ihu n'iji ya eme ihe dị ka ọgwụ pesticide sitere n'okike ya.
5. Nnyocha na mmepe
◊ Ọmụmụ biochemical: A na-ejikarị caffeic acid eme nyocha ụlọ nyocha iji mụọ mmetụta ya na usoro ndu dị iche iche yana ngwa ọgwụgwọ nwere ike.
Ajụjụ ndị emetụtara ị nwere ike ịmasị gị:
♦ Kedu ihe mmetụta dị na yacaffeic acid ?
A na-ewerekarị caffeic acid dị ka ọ dị mma ma ọ bụrụ na a na-eri ya n'oke oke site na isi nri. Otú ọ dị, dị ka ogige ọ bụla, ọ nwere ike inwe mmetụta ndị nwere ike ime, karịsịa mgbe a na-ewere ya na nnukwu doses ma ọ bụ dị ka mgbakwunye na-etinye uche. Nke a bụ mmetụta ụfọdụ nwere ike ime:
Nsogbu eriri afọ:
Ụfọdụ ndị mmadụ nwere ike ịnwe mgbakasị afọ, ọgbụgbọ, ma ọ bụ afọ ọsịsa mgbe ha na-eri nnukwu caffeic acid.
Mmeghachi omume nfụkasị ahụ:
Ọ bụ ezie na ọ dị ụkọ, ụfọdụ ndị nwere ike ịnwe mmeghachi omume nfụkasị na caffeic acid ma ọ bụ osisi ndị nwere ya, na-eduga na mgbaàmà dị ka itching, ọkụ ọkụ, ma ọ bụ ọzịza.
Mmekọrịta ya na ọgwụ:
Caffeic acid nwere ike iji ọgwụ ụfọdụ emekọrịta ihe, ọkachasị ndị na-emetụta enzymes imeju. Nke a nwere ike gbanwee ịdị irè nke ọgwụ.
Mmetụta Hormonal:
Enwere ụfọdụ ihe akaebe na caffeic acid nwere ike imetụta ọkwa homonụ, nke nwere ike bụrụ nchegbu maka ndị nwere ọnọdụ mmetụta homonụ.
Nchegbu Oxidative:
Ọ bụ ezie na caffeic acid bụ antioxidant, oke oriri nwere ike ibute nrụgide oxidative n'ọnọdụ ụfọdụ, ọkachasị ma ọ bụrụ na ọ na-akpaghasị nguzozi nke antioxidants ndị ọzọ na ahụ.
♦ Ọ bụcaffeic aciddị ka caffeine?
Caffeic acid na caffeine abụghị otu; ha bụ ogige dị iche iche nwere ụdị kemịkal dị iche iche, akụrụngwa na ọrụ dị iche iche.
IHE ọdịghị mkpa:
1.Chemical Structure:
Caffeic acid:Ngwakọta phenolic nwere usoro kemịkalụ C9H8O4. Ọ bụ hydroxycinnamic acid.
Caffeine:Ihe na-akpali akpali nke klaasị xanthine, yana usoro kemịkal C8H10N4O2. Ọ bụ methylxanthine.
2. Isi mmalite:
Caffeic acid:Achọtara n'ụdị osisi, mkpụrụ osisi, na akwụkwọ nri, ọkachasị na kọfị, mkpụrụ osisi, na ahịhịa ụfọdụ.
Caffeine:A na-achọta ya na kọfị kọfị, akwụkwọ tii, agwa cacao, na ụfọdụ ihe ọṅụṅụ dị nro.
3. Mmetụta ndu:
Caffeic acid:Amara maka antioxidant ya, mgbochi mkpali, yana uru ahụike nwere ike, gụnyere nkwado maka ahụike obi na akwara anụ ahụ.
Caffeine:A Central ụjọ usoro stimulant nke nwere ike dịkwuo njikere, belata ike ọgwụgwụ, na melite itinye uche.
4. Na-eji:
Caffeic acid:Ejiri ya na nri dị ka ihe nchekwa, na ihe ịchọ mma maka ahụike anụ ahụ, na nyocha maka mmetụta ọgwụgwọ ya nwere ike.
Caffeine:A na-ejikarị ihe ọṅụṅụ na-aba n'anya maka mmetụta ya na-akpali akpali ma na-ejikwa ya na ọgwụ ụfọdụ maka enyemaka mgbu na ịmụrụ anya.
Oge nzipu: Ọkt-09-2024
