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Nkọwa ngwaahịa
Famotidine bụ onye na-anabata ihe nnabata H2, nke a na-ejikarị agwọ ọrịa ndị metụtara gastric acid. Ọ na-egbochi ndị na-anabata histamine H2 na cell parietal gastric, na-ebelata secretion nke gastric acid, ma si otú a na-ebelata mgbaàmà nke oke acid gastric kpatara. Ihe na-esonụ bụ mmeghe zuru ezu na Famotidine:
Isi atụmatụ na ọrụ
1. Mechanism: Famotidine na-egbochi mmepụta nke acid gastric ma belata acidity dị n'ime afọ site na ịhọrọ imegide ndị na-anabata H2 na sel parietal gastric.
2. Ngosipụta:
Gastroesophageal Reflux Disease (GERD): A na-eji ebelata mgbaàmà nke reflux acid kpatara, dị ka nrekasi obi na regurgitation acid.
- ọnya peptic: eji agwọ ọnya afọ na ọnya duodenal ma kwalite ọgwụgwọ ọnya.
-Mgbochi Ọrịa Gastric Acid metụtara: N'ọnọdụ ụfọdụ, Famotidine nwere ike iji gbochie ọrịa gastric acid metụtara nke ọgwụ dịka NSAIDs kpatara.
Ụdị 3. Dosage:Famotidine na-adịkarị n'ụdị mbadamba ụrọ na ntụtụ, ndị ọrịa nwere ike were ya dịka ndụmọdụ dọkịta siri dị.
4. Mmeghachi omume ọjọọ:A na-anabata Famotidine nke ọma, mana ụfọdụ mmetụta nwere ike ime, dị ka isi ọwụwa, isi ọwụwa, afọ ọsịsa ma ọ bụ afọ ntachi.
5.Akpachara anya maka ojiji:Mgbe ha na-eji Famotidine, ndị ọrịa kwesịrị ịgwa ndị dọkịta ha ma ọ bụrụ na ha nwere nsogbu ahụike ndị ọzọ ma ọ bụ na-aṅụ ọgwụ ndị ọzọ iji zere mmekọrịta ọgwụ ike.
Nchịkọta
Famotidine bụ onye na-anabata H2 dị irè, nke a na-ejikarị agwọ ọrịa ndị metụtara gastric acid, dị ka ọrịa reflux gastroesophageal na ọnya peptic. Site na ibelata secretion acid gastric, Famotidine nwere ike belata mgbaàmà ndị metụtara ya ma kwalite ọgwụgwọ. Mgbe ị na-eji ya, ị kwesịrị ịgbaso ntuziaka dọkịta iji hụ na nchekwa na ịdị irè.
COA
| Ihe | Nkọwapụta | Nsonaazụ |
| Ọdịdị | Gbanyụọ-acha ọcha ma ọ bụ ntụ ntụ ọcha | Ọcha ntụ ntụ |
| HPLC njirimara | Nkwekọ na ntụnye aka oge njigide isi ihe | Na-akwado |
| Ntughari pụrụ iche | + 20.0.-+ 22.0. | + 21. |
| Ọla dị arọ | ≤ 10pm | <10ppm |
| PH | 7.5-8.5 | 8.0 |
| Ọnwụ na ihicha | ≤ 1.0% | 0.25% |
| Ndu | ≤3pm | Na-akwado |
| Arsenic | ≤1pm | Na-akwado |
| Cadmium | ≤1pm | Na-akwado |
| Mercury | ≤0. 1ppm | Na-akwado |
| Ebe mgbaze | 250.0 ℃ ~ 265.0 ℃ | 254.7 ~ 255.8 ℃ |
| Ihe fọdụrụ na mgbanye | ≤0. 1% | 0.03% |
| Hydrazine | ≤2pm | Na-akwado |
| Nnukwu njupụta | / | 0.21g / ml |
| Njupụta enwetara | / | 0.45g / ml |
| Nyocha (Famotidine) | 99.0% ~ 101.0% | 99.65% |
| Ngụkọta aerobes ọnụ | ≤1000CFU/g | <2CFU/g |
| Ebu & Yist | ≤100CFU/g | <2CFU/g |
| E.coli | Ihe ọjọọ | Ihe ọjọọ |
| Salmonella | Ihe ọjọọ | Ihe ọjọọ |
| Nchekwa | Chekwaa n'ebe dị jụụ & ihicha, debe ọkụ siri ike. | |
| Mmechi | tozuru oke | |
Ọrụ
Famotidine bụ onye na-anabata H2, nke a na-ejikarị agwọ ọrịa ndị metụtara gastric acid. Ọ na-arụ ọrụ site na igbochi histamine H2 ndị na-anabata ya na sel parietal gastric, na-ebelata secretion acid gastric. Ndị a bụ isi ọrụ Famotidine:
1. Belata secretion gastric acid:Famotidine na-ebelata nke ọma secretion acid gastric site na imegide ndị na-anabata H2, na-enyere aka belata mgbaàmà nke oke acid gastric kpatara.
2. Ọgwụgwọ ọrịa reflux gastroesophageal (GERD):Enwere ike iji Famotidine na-agwọ ọrịa reflux gastroesophageal, na-ebelata nrekasi obi na ahụ erughị ala nke reflux acid gastric kpatara.
3. Ọgwụgwọ ọnya peptic:A na-eji Famotidine agwọ ọnya afọ na ọnya duodenal, na-akwalite ọgwụgwọ ọnya, ma belata ohere nke nlọghachi.
4.Mgbochi nke secretion gastric acid postoperative:Mgbe ụfọdụ ịwa ahụ gasịrị, enwere ike iji Famotidine gbochie oke acid gastric ma belata ihe ize ndụ nke nsogbu mgbe ịwachara ahụ gasịrị.
5. Wepụ ihe mgbaàmà metụtara afọ acid:Famotidine nwere ike inye aka belata mgbaàmà nke acid afọ kpatara, dị ka mgbu afọ, mgbaze na afọ ntachi.
Ojiji
Famotidine na-adịkarị n'ụdị mbadamba ọnụ ma ọ bụ injections, na usoro ọgwụgwọ akọwapụtara na ugboro ole a ga-edozi ya dabere na ndụmọdụ dọkịta gị.
Mmeghachi omume ọjọọ
A na-anabata Famotidine nke ọma, mana ụfọdụ mmetụta nwere ike ime, dị ka isi ọwụwa, isi ọwụwa, afọ ọsịsa, ma ọ bụ afọ ntachi.
N'ikpeazụ, Famotidine bụ onye na-anabata H2 dị irè, nke a na-ejikarị agwọ ọrịa ndị metụtara gastric acid, na-enyere ndị ọrịa aka ịkwụsị mgbaàmà ma kwalite ọgwụgwọ. Mgbe ị na-eji ya, ị kwesịrị ịgbaso ntuziaka dọkịta iji hụ na nchekwa na ịdị irè.
Ngwa
Ngwa nke Famotidine na-elekwasị anya na ọgwụgwọ ọrịa ndị metụtara gastric acid, gụnyere akụkụ ndị a:
1. Ọrịa reflux gastroesophageal (GERD):A na-eji Famotidine ewepụ ihe mgbaàmà nke reflux acid kpatara, dị ka nrekasi obi, regurgitation acid, na mgbu obi. Ọ na-ebelata ihe mgbaàmà ndị a site n'ibelata nsị nke acid afọ.
2. ọnyá afọ:A na-eji Famotidine agwọ ọnya afọ na ọnya duodenal, na-enyere aka ịkwalite ọgwụgwọ ọnya ma belata mgbu na ahụ erughị ala metụtara ya.
3.Mgbochi ọrịa ndị metụtara gastric acid:Enwere ike iji Famotidine gbochie ọrịa ndị metụtara gastric acid nke ọgwụ ndị dị ka ọgwụ na-adịghị egbochi mkparị (NSAIDs), karịsịa na ndị ọrịa nwere nnukwu ihe ize ndụ.
4. Zollinger-Ellison ọrịa:A nwekwara ike iji Famotidine gwọọ ọrịa a na-adịghị ahụkebe, nke na-ebute oke mmiri nke acid afọ.
5. njikwa acid gastric nke ịwachara arụ ọrụ:Mgbe ụfọdụ ịwa ahụ gasịrị, enwere ike iji Famotidine chịkwaa secretion acid gastric ma belata ihe ize ndụ nke nsogbu mgbe ịwachara ahụ gasịrị.
Ojiji
A na-enye Famotidine n'ụdị mbadamba ọnụ. Ndị ọrịa kwesịrị ịnara ya dịka ndụmọdụ dọkịta ha siri dị. Usoro onunu ogwu na ugboro ojiji ga-adịgasị iche dabere na ọnọdụ akọwapụtara.
Ihe ndetu
Mgbe ha na-eji Famotidine, ndị ọrịa kwesịrị ịgwa ndị dọkịta ha ma ọ bụrụ na ha nwere nsogbu ahụike ndị ọzọ ma ọ bụ na-aṅụ ọgwụ ndị ọzọ iji zere mmekọrịta ọgwụ ike. Na mgbakwunye, ọ bụ ezie na Famotidine nwere ike ịchịkwa secretion acid gastric nke ọma, ndị ọrịa kwesịrị ịchọ nlekọta ahụike ma ọ bụrụ na mgbaàmà na-aga n'ihu ma ọ bụ na-akawanye njọ.
N'ikpeazụ, Famotidine bụ onye na-anabata ndị na-anabata H2 dị irè nke a na-ejikarị na-agwọ ọrịa ndị metụtara gastric acid, na-enyere ndị ọrịa aka ịkwụsị mgbaàmà ma kwalite ọgwụgwọ. Ekwesịrị iji ya n'okpuru nduzi nke dọkịta iji hụ na nchekwa na ịdị irè.
Ngwungwu & Nbunye
