• Dab tsi yogTetrahydrocurcuminurcumin ?
Rhizoma Curcumae Longae yog Diav Rhiza ntawm Curcumae Longae L. Nws yog dav siv los ua cov zaub mov xim thiab tshuaj tsw qab. Nws cov tshuaj lom neeg muaj pes tsawg leeg tsuas yog suav nrog curcumin thiab volatile roj, dua li smamcharides thiab Sterols. Curcumin (CUR), raws li ib lub ntuj polyphenol nyob rau hauv curcuma nroj tshuag, suav nrog ntau yam kev tawm tsam tshuaj, suav nrog cov qog ua si thiab tiv thaiv Alzheimer tus kab mob (ad).
Curcumin tau nrawm dua ntais hauv lub cev ua rau cov kua roj flucuronic acid conjugates, thiab hexahydrocurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurs, thiab hexahydrocurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurs Kev tshawb fawb sim tau lees paub tias Curcumin muaj qhov ruaj khov (saib cov photodecposition), tsis muaj dej solubility thiab qis bioavailability. Yog li ntawd, nws lub ntsiab metabolic sib xyaw tetrahydrocurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcurcur hauv tsev thiab txawv teb chaws nyob rau hauv xyoo tas los no.
Tetrahydrocurcuminurcumin(THC), raws li cov metabolite feem ntau ntawm curcumin kev tsim tawm thaum lub plab me me, tuaj yeem raug rho tawm ntawm cov hnyuv thiab daim siab tom qab curcumin kev tswj hwm rau tib neeg lossis nas. Cov qauv molecular yog c21h26o6, qhov hnyav molecular yog 372.2, lub ntom yog 1.222, thiab lub taw tes melting yog 95 ℃ -97 ℃.
• Cov txiaj ntsig ntawmTetrahydrocurcuminurcuminHauv kev tu tawv nqaij?
1. Cov nyhuv rau Melanin Ntau Lawm
TetraYDRocurcurcumin tuaj yeem txo cov ntsiab lus melanin hauv B16F10 lub hlwb. Thaum cov qauv sib piv ntawm Tetrathydrocurcurcurcumin (25, 50, 200μ1, 80% rau 74.34%, 34.3%, feem pua.
TetraYDRocurcurcumin tau nyob rau inhibit tyrosinase kev ua hauv B16f10 hlwb. Thaum kev sib raug zoo ntawm tetrahydrocurcurcurcurcumin (100 thiab 200μ1
2. Anti-doice
Thov saib cov duab duab nas hauv qab no: CTRL (tswj), UV (UVB), thc (UVB), thc, yaj hauv 0.5% sodium carboxymethyl cellulose). Cov duab ntawm daim tawv nqaij nyob sab nraum qab ntawm km nas nyob tom qab 10 lub lis piam tom qab tsim kev kho mob THC thiab UVA irradiation. Cov pab pawg sib txawv nrog sib npaug UVA Flux hluav taws xob mus rau kev laus kev laus tau raug ntsuas los ntawm Bissett cov qhab nia. Cov txiaj ntsig tau nthuav tawm yog qhov txhais tau tias yog tus qauv sib txawv (n = 12 / pawg). * P <0.05, ** p
Los ntawm cov tsos, piv nrog cov pawg tswj kav ib txwm, cov tawv nqaij ntawm cov qauv kev tswj hwm thiab tuab, nrog kev hloov tawv zoo li tawv, uas yog cov khoom tshwm sim sib txawv. Piv nrog tus qauv tswj hwm, kev puas tsuaj degree ntawmtetrahydrocurcuminurcumin100 mg / kg pab pawg tau qis dua li cov qauv kev tswj hwm, thiab tsis muaj pom ntawm daim tawv nqaij, tsuas yog pom me me thiab cov tawv nqaij zoo nkauj tau pom.
3.Qhov antioxidant
TetraYDRocurcurcumin tau nce sod theem, txo qis qib LDH thiab nce GSH-PX theem hauv HACAT cov ntshav.
Scavenging dpph dawb radicals
TustetrahydrocurcuminurcuminKev daws tau diluted los ntawm 10, 50, 80, 100, 100, 200, 400, 1600, 1600, 1600, 16 tov kev daws teeb meem ntawm qhov sib piv ntawm 1: 5. Tom qab cov tshuaj tiv thaiv ntawm chav sov rau 30min, tus nqi nqus tau txiav txim siab ntawm 517nm. Qhov tshwm sim yog qhia hauv daim duab:
4. Inhibit oppe o
Cov kev sim sim qhia tau tias lub qhov txhab kho kom zoo ntawm cov nas tau pom tsis tu ncua thiab zoo dua thiab zoo dua, qhov kev txiav txim siab zoo dua yog THC-slns gel>
THC> Kev tswj kom zoo.
Hauv qab no yog tus sawv cev cov duab ntawm kev puas tsuaj nas mouse qauv, A4 thiab A6 uas qhia tau tias cov tawv nqaij zoo li qub, thiab A10 uas qhia txog cov nqaij ntawd ib txwm muaj (SLN), feem.
• Daim ntawv thov ntawmTetrahydrocurcuminurcuminHauv cov tshuaj pleev ib ce
1.Cov saib xyuas khoom:
Los tiv thaiv cov khoom lag luam:Siv hauv kev tawm tsam cov qoob loo thiab cov ntshav tawm los pab txo cov tawv thiab cov kab zoo thiab txhim kho cov tawv nqaij elasticity.
Cov khoom ntxuav ntxuav hniav dawb:Ntxiv rau ntxuav hniav dawb thiab cream los pab txhim kho cov laus tawv nqaij tsis sib xws thiab pob.
2.anti-inflammatory khoom:
Siv nyob rau hauv cov khoom tu tawv nqaij zoo xws li soothing thiab kho cov tshuaj pleev kom txo qis thiab voos.
3.Cleaning khoom:
Ntxiv rau cov tshuaj ntxuav kom huv thiab exfoliants los pab ntxuav cov tawv nqaij thiab muab cov txiaj ntsig tua kab mob kom tiv thaiv pob txuv.
4.Sunscreen Khoom:
Ua raws li antioxidant kom txhim kho qhov ua tau zoo ntawm cov tshuaj pleev thaiv hnub thiab tiv thaiv daim tawv nqaij los ntawm UV rays.
5.Qhov ntsej muag:
Siv hauv ntau lub ntsej muag ntsej muag kom muab kev noj haus sib sib zog thiab kho kom zoo, txhim kho cov tawv nqaij ua kom tawv nqaij.
TetrahydrocurcuminurcuminYog siv dav hauv cov tshuaj pleev ib ce, npog cov kev saib xyuas tawv nqaij, tu, kev tiv thaiv hnub thiab lwm daim teb. Nws yog kev nyiam rau nws cov antioxidant, anti-inflampatory thiab ntxuav hniav dawb.
Lub Sijhawm Post: Oct-10-2024
