Hauv kev tsim kho tshiab, cov kws tshawb fawb tau nthuav tawm lub peev xwm ntawm matrine, ib qho khoom siv ntuj tsim tau los ntawm cov hauv paus ntawm cov nroj tsuag Sophora flavescens, hauv kev tawm tsam kev mob qog noj ntshav. Qhov kev tshawb pom no qhia txog kev nce qib tseem ceeb hauv thaj chaw ntawm oncology thiab muaj peev xwm los hloov kho kev kho mob qog noj ntshav.
Dab tsi yogMatrine?
Matrine tau ntev tau siv nyob rau hauv cov tshuaj suav tshuaj rau nws cov tshuaj tiv thaiv kab mob thiab tiv thaiv qog noj ntshav. Txawm li cas los xij, nws cov txheej txheem tshwj xeeb ntawm kev nqis tes ua tseem tsis tau paub txog tam sim no. Cov kws tshawb fawb tsis ntev los no tau ua cov kev tshawb fawb dav dav los daws cov kab mob molecular los ntawm cov matrine exerts nws los tiv thaiv mob qog noj ntshav.
Los ntawm lawv cov kev tshawb fawb, cov kws tshawb fawb tau pom tias matrine muaj lub zog los tiv thaiv kev loj hlob thiab pro-apoptotic zog, txhais tau tias nws tuaj yeem cuam tshuam kev loj hlob ntawm cov qog nqaij hlav cancer thiab ua rau lawv cov txheej txheem cell tuag. Qhov kev ua ob no ua rau matrine yog ib tus neeg sib tw zoo rau kev txhim kho kev kho mob qog noj ntshav tshiab.
Tsis tas li ntawd, cov kev tshawb fawb tau qhia tiasmatrinetuaj yeem cuam tshuam kev tsiv teb tsaws thiab kev cuam tshuam ntawm cov qog nqaij hlav cancer, uas yog cov txheej txheem tseem ceeb hauv kev kis mob qog noj ntshav. Qhov no qhia tau hais tias matrine yuav tsis tsuas yog siv tau zoo hauv kev kho cov qog nqaij hlav thawj zaug tab sis kuj tseem tiv thaiv cov kab mob metastasis, ib qho kev sib tw loj hauv kev tswj mob qog noj ntshav.
Ntxiv nrog rau nws cov kev cuam tshuam ncaj qha rau cov qog nqaij hlav cancer, matrine tau pom los hloov cov qog microenvironment, inhibiting tsim cov hlab ntsha tshiab uas yog qhov tseem ceeb rau kev loj hlob ntawm cov qog. Cov cuab yeej no los tiv thaiv angiogenic txuas ntxiv txhim kho lub peev xwm ntawm matrine ua tus neeg sawv cev tiv thaiv kab mob.
Kev tshawb pom ntawm matrine lub peev xwm tiv thaiv kab mob qog noj ntshav tau ua rau muaj kev zoo siab hauv zej zog kev tshawb fawb, nrog cov kws tshawb fawb tam sim no tsom mus rau kev tshawb nrhiav ntxiv nws cov kev siv kho mob. Kev sim tshuaj kho mob tab tom ntsuas los ntsuas kev nyab xeeb thiab kev ua tau zoo ntawm kev kho mob matrine hauv cov neeg mob qog noj ntshav, muab kev cia siab rau kev txhim kho kev kho mob qog noj ntshav tshiab thiab txhim kho.
Hauv kev xaus, kev tshwm sim ntawmmatrine covCov khoom tiv thaiv kab mob qog noj ntshav sawv cev rau qhov tseem ceeb hauv kev sib ntaus sib tua tiv thaiv mob qog noj ntshav. Nrog nws cov txheej txheem ntau yam ntawm kev nqis tes ua thiab cov txiaj ntsig tau txais txiaj ntsig zoo, matrine tuav cov lus cog tseg zoo li riam phom yav tom ntej hauv kev tawm tsam tus kab mob loj heev. Raws li kev tshawb fawb hauv cheeb tsam no txuas ntxiv nthuav dav, lub peev xwm ntawm matrine hauv kev hloov pauv kev kho mob qog noj ntshav tsis tuaj yeem ua dhau los.
Post lub sij hawm: Sep-02-2024
