• Dab tsi yogLycopene ?
Lycopene yog lub ntuj carotenoid, feem ntau pom muaj nyob rau hauv txiv hmab txiv ntoo thiab zaub xws li txiv lws suav. Nws cov qauv tshuaj muaj 11 conjugated ob daim ntawv cog lus thiab 2 non-conjugated ob daim ntawv cog lus, thiab muaj zog antioxidant.
Lycopene tuaj yeem tiv thaiv cov phev los ntawm ROS, yog li txhim kho cov phev motility, inhibiting prostate hyperplasia, prostate cancer cell carcinogenesis, txo qhov mob ntawm daim siab rog, atherosclerosis thiab coronary kab mob, txhim kho tib neeg kev tiv thaiv, thiab txo cov tawv nqaij puas los ntawm ultraviolet teeb.
Tib neeg lub cev tsis tuaj yeem tsim cov lycopene los ntawm nws tus kheej, thiab tsuas yog noj los ntawm zaub mov xwb. Tom qab nqus tau, nws tsuas yog khaws cia hauv daim siab. Nws tuaj yeem pom hauv plasma, seminal vesicles, prostate thiab lwm yam ntaub so ntswg.
• Cov txiaj ntsig yog dab tsiLycopeneRau Txiv Neej Kev Npaj Kev Npaj?
Tom qab RAGE ua kom muaj zog, nws tuaj yeem ua rau muaj kev cuam tshuam ntawm tes thiab ua rau kev tsim ROS, yog li cuam tshuam rau cov phev ua haujlwm. Raws li muaj zog antioxidant, lycopene tuaj yeem tua cov pa oxygen, tshem tawm ROS, thiab tiv thaiv cov phev lipoproteins thiab DNA los ntawm kev oxidized. Cov kev tshawb fawb tau pom tias lycopene tuaj yeem txo qib ntawm receptor rau qib siab glycation kawg khoom (RAGE) hauv tib neeg cov phev, yog li txhim kho cov phev motility.
Lycopene cov ntsiab lus siab hauv cov noob qes ntawm cov txiv neej noj qab haus huv, tab sis qis dua hauv cov txiv neej infertile. Cov kev tshawb fawb soj ntsuam tau pom tias lycopene tuaj yeem txhim kho qhov zoo ntawm cov phev txiv neej. Cov txiv neej tsis muaj menyuam muaj hnub nyoog 23 txog 45 xyoos tau hais kom noj lycopene ntawm qhov ncauj ob zaug ib hnub. Rau lub hlis tom qab, lawv cov phev concentration, kev ua ub no thiab cov duab raug kuaj dua. Peb-plaub ntawm cov txiv neej tau txhim kho cov phev motility thiab morphology, thiab phev concentration tau zoo heev.
• Cov txiaj ntsig yog dab tsiLycopeneRau txiv neej Prostate?
1. Prostatic Hyperplasia
Prostatic hyperplasia yog ib hom kab mob hauv cov txiv neej, thiab nyob rau xyoo tas los no, qhov tshwm sim tau poob qis heev. Cov tsos mob ntawm cov zis qis (urinary urgency / nquag tso zis / tso zis tsis tiav) yog cov tsos mob tseem ceeb, uas cuam tshuam rau lub neej zoo ntawm cov neeg mob.
Lycopenetuaj yeem cuam tshuam qhov kev loj hlob ntawm prostate epithelial hlwb, txhawb kev apoptosis hauv cov ntaub so ntswg prostate, txhawb kev sib txuas ntawm cov kab sib txuas sib txuas los tiv thaiv kev faib tawm ntawm tes, thiab txo cov qib ntawm cov kab mob xws li interleukin IL-1, IL-6, IL-8 thiab qog necrosis. factor (TNF-α) los tiv thaiv cov teebmeem.
Cov kev sim tshuaj tau pom tias lycopene tuaj yeem txhim kho prostate hyperplasia thiab zais zis cov leeg nqaij fiber ntau hauv cov neeg rog thiab txo cov tsos mob ntawm tus txiv neej qis qis. Lycopene muaj kev kho mob zoo thiab kev txhim kho ntawm cov txiv neej qis cov tsos mob tshwm sim los ntawm prostate hypertrophy thiab hyperplasia, uas muaj feem xyuam rau cov muaj zog antioxidant thiab anti-inflammatory teebmeem ntawm lycopene.
2. Prostate Cancer
Muaj ntau cov ntaub ntawv kho mob txhawb qhov ntawdlycopeneHauv kev noj zaub mov txhua hnub ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv qog noj ntshav prostate, thiab kev noj lycopene tsis zoo cuam tshuam nrog kev pheej hmoo ntawm mob qog noj ntshav prostate. Nws cov txheej txheem ntseeg tau hais tias muaj feem xyuam rau kev cuam tshuam rau kev nthuav tawm ntawm cov qog nqaij hlav thiab cov proteins, inhibiting qog nqaij hlav qog noj ntshav thiab adhesion, thiab txhim kho kev sib txuas lus intercellular.
Kev sim ntawm cov nyhuv ntawm lycopene ntawm kev ciaj sia ntawm tib neeg cov qog nqaij hlav qog noj ntshav: Hauv kev sim tshuaj kho mob, lycopene tau siv los kho tib neeg cov kab mob qog noj ntshav ntawm tes DU-145 thiab LNCaP.
Cov txiaj ntsig tau pom tiaslycopenemuaj cov nyhuv inhibitory tseem ceeb ntawm kev loj hlob ntawm DU-145 hlwb, thiab cov nyhuv inhibitory tau pom ntawm 8μmol / L. Cov nyhuv inhibitory ntawm lycopene ntawm nws tau zoo sib xws nrog cov koob tshuaj, thiab qhov siab tshaj plaws inhibition tuaj yeem ncav cuag 78%. Nyob rau tib lub sijhawm, nws tuaj yeem cuam tshuam qhov kev loj hlob ntawm LNCaP, thiab muaj kev sib raug zoo ntawm koob tshuaj. Qhov siab tshaj plaws inhibition tus nqi ntawm 40μmol / L tuaj yeem ncav cuag 90%.
Cov txiaj ntsig tau pom tias lycopene tuaj yeem cuam tshuam kev loj hlob ntawm prostate hlwb thiab txo qhov kev pheej hmoo ntawm prostate qog nqaij hlav cancer.
Post lub sij hawm: Nov-20-2024
