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Ginseng Extract Ginsenosides - Cov txiaj ntsig, kev siv, Sab Nrauv thiab ntau dua

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Dab tsi yogGinsenosides?

Ginsenosides yog cov khoom xyaw tseem ceeb ntawm ginseng. Lawv muaj nyob rau hauv triterpenoid glycoside tebchaw thiab tuaj yeem muab faib ua protopanaxadiol saponins (PPD-type saponins), protopanaxatriol saponins (PPT-type saponins) thiab oleanane-type. Ntau tshaj 40 ginsenosides tau raug cais tawm ntawm cov hauv paus ginseng.

Ginsenosides muaj ntau yam kev kho mob xws li tshuaj tua kab mob antioxidant, tiv thaiv kab mob, vasodilation, tiv thaiv kev ua xua, thiab tiv thaiv ntshav qab zib. Qee cov ginsenosides qhia lawv cov khoom tiv thaiv kabmob kheesxaws los ntawm kev txo cov DNA puas tsuaj, txo tus tswv tsev rau kev hloov pauv, nce kev tiv thaiv kab mob thiab cell apoptosis. Tsis tas li ntawd, ginsenosides tuaj yeem txhim kho qhov ua tau zoo ntawm cov tshuaj siv tshuaj khomob thiab tiv thaiv kev puas tsuaj rau cov ntaub so ntswg.

Cov ntsiab lus ntawm Tag Nrho Ginsenosides Nyob rau ntau qhov chaw ntawm Ginseng

Ib feem

Tag nrho Ginsenosides Cov ntsiab lus

Lateral cag

60.5%

Buds

15%

Ginseng nplooj

7.6% -12.6%

Ginseng fibrous cov hauv paus hniav

8.5% -11.5%

Ginseng tawv nqaij

8.0% -8.8%

Ginseng nplooj

2% -7%

Ginseng hluas cag

3%

Noob

0.7%

Hom Thiab Tshuaj Zoo NtawmGinsenosides

Ginsenosides txhua tus muaj cov qauv yooj yim zoo sib xws, txhua tus muaj sterane steroid nucleus nrog 30 carbon atoms teem rau plaub lub nplhaib. Lawv tau muab faib ua ob pawg raws li cov qauv glycoside sib txawv: hom dammarane thiab hom oleanane.

Hom Dammarane suav nrog ob pawg:

Ginsenoside type-A, aglycone yog 20 (S)-protopanaxadiol. Muaj cov ginsenosides feem ntau, xws li ginsenoside Rg3, Rb1, Rb2, Rb3, Rc, Rd, Rh2 thiab glycoside PD;

Ginsenoside type-B, aglycone yog 20 (S)-protopanaxadiol. Muaj ginsenoside Re, Rg1, Rg2, Rh1 thiab glycoside PT.

Oleanane hom: oleanolic acid type-C, aglycone yog oleanolic acid.

Tag nrho cov saponins tsis yog hemolytic, hom A yog anti-hemolytic, thaum hom B thiab hom C yog hemolytic.

Ginsenoside Hom

Kev ua tau zoo

Rh2

Nws muaj cov nyhuv ntawm inhibiting metastasis ntawm cov qog nqaij hlav cancer rau lwm yam kabmob, txhim kho lub cev tiv thaiv kab mob, thiab ua kom lub cev muaj zog sai. Nws muaj cov txiaj ntsig tseem ceeb los tiv thaiv metastasis ntawm cov qog nqaij hlav cancer, thiab tuaj yeem siv nrog kev phais kom txhim kho qhov txhab thiab lub cev rov qab los tom qab kev phais. Qhov tseeb bioavailability yog (16.1 ± 11.3)%.

Rg

Nws muaj cov txiaj ntsig ntawm kev txhawb nqa lub hauv paus paj hlwb, tiv thaiv kev qaug zog, txhim kho kev nco thiab kev kawm muaj peev xwm, thiab txhawb nqa DNA thiab RNA synthesis. Nws muaj cov txiaj ntsig ntawm kev txhawb nqa lub hauv paus paj hlwb, tiv thaiv kev qaug zog, txhim kho kev nco thiab kev kawm muaj peev xwm, thiab txhawb nqa DNA thiab RNA synthesis.

Rg 1

Nws tuaj yeem txo qhov qaug zog sai sai, txhim kho kev kawm thiab nco, thiab ncua kev laus. Nws muaj cov nyhuv ntawm stimulating lub hauv paus paj hlwb thiab inhibiting platelet aggregation.

Rg 2

Nws muaj kev tiv thaiv kev poob siab, txhim kho myocardial ischemia thiab hypoxia sai, thiab kho thiab tiv thaiv kab mob plawv.

Rg 3

Nws tuaj yeem ua rau G2 theem ntawm lub cev xeeb tub, inhibit synthesis ntawm cov proteins thiab ATP nyob rau hauv pre-mitotic theem ntawm cov qog nqaij hlav cancer, ua kom qeeb thiab loj hlob ntawm cov qog nqaij hlav cancer, thiab muaj cov teebmeem ntawm inhibiting qog nqaij hlav hlwb infiltration, tiv thaiv qog cell metastasis, txhawb cov qog cell apoptosis, thiab inhibiting qog cell loj hlob.

Rg 5

Inhibit cancer cell infiltration, tiv thaiv qog cell metastasis, txhawb qog cell apoptosis, inhibit qog cell loj hlob

Rb 1

American ginseng (American ginseng) muaj cov ntsiab lus siab tshaj plaws thiab muaj peev xwm cuam tshuam rau cov tsiaj qes thiab kev loj hlob ntawm embryonic nas. Nws muaj kev ua haujlwm ntawm kev txhim kho choline system, ua kom cov synthesis thiab tso tawm ntawm acetylcholine thiab txhim kho kev nco.

Rb 2

DNA thiab RNA synthesis txhawb nqa, kev tswj lub hlwb hauv nruab nrab muaj cov teebmeem ntawm inhibiting lub hauv nruab nrab paj hlwb, txo cov calcium intracellular, tiv thaiv oxidation, tshem tawm cov dawb radicals hauv lub cev thiab txhim kho myocardial ischemia-reperfusion raug mob.

Rc

Ginsenoside-Rc yog steroid molecule hauv ginseng. Nws muaj cov haujlwm ntawm inhibiting cov qog nqaij hlav cancer. Nws tuaj yeem ua kom cov phev ua haujlwm.

Rb 3

Nws tuaj yeem txhim kho myocardial muaj nuj nqi thiab tiv thaiv lub cev tiv thaiv kab mob. Nws tuaj yeem siv los kho myocardial contractile tsis ua haujlwm los ntawm ntau yam laj thawj.

Rh

Nws muaj cov teebmeem ntawm inhibiting lub hauv nruab nrab lub paj hlwb, hypnotic, analgesic, calming, antipyretic, thiab txhawb cov ntshav protein synthesis.

Rh1

Nws muaj cov teebmeem ntawm kev txhawb lub siab cell proliferation thiab DNA synthesis, thiab tuaj yeem siv los kho thiab tiv thaiv kab mob siab thiab cirrhosis.

R0

Nws muaj anti-inflammatory, detoxifying, thiab anti-thrombotic teebmeem, inhibits acidic platelet aggregation, thiab muaj anti-hepatitis teebmeem thiab activates macrophages.

Rh3

Cov teebmeem ntawm ginsenoside Rh3 ntawm kev loj hlob thiab apoptosis ntawm tib neeg coloncancer hlwb SW480.

Cov khoom xyaw tiv thaiv qog

Cov khoom xyaw

Kev ua tau zoo

Rh2

Ginsenoside Rh2 monomer muaj cov nyhuv inhibitory ntawm kev loj hlob ntawm cov qog nqaij hlav cancer, tuaj yeem ua rau cov qog cell apoptosis, thim rov qab txawv txav ntawm cov qog hlwb, thiab tiv thaiv qog nqaij hlav metastasis. Thaum siv ua ke nrog cov tshuaj chemotherapy, nws tuaj yeem txhim kho kev ua tau zoo thiab txo cov tshuaj toxicity. Ntxiv nrog rau cov nyhuv tiv thaiv qog, ginsenosides muaj cov txiaj ntsig ntawm kev txhim kho lub cev tiv thaiv kab mob, tshuaj tua kab mob, txhim kho cov hlab plawv thiab cerebrovascular cov ntshav tsis txaus, tswj lub hauv nruab nrab lub paj hlwb, tiv thaiv qaug zog, thiab ncua kev laus.

Rh1

Nws tuaj yeem inhibit qhov adhesion thiab infiltration ntawm cov qog hlwb, tiv thaiv kev tsim cov hlab ntsha tshiab rau cov qog nqaij hlav cancer, yog li inhibiting qog kev loj hlob, kis thiab metastasis, thiab muaj cov haujlwm tseem ceeb los tiv thaiv qog noj ntshav. Nws tuaj yeem txhim kho qhov txo qis hauv cov qe ntshav dawb uas tshwm sim los ntawm kev siv hluav taws xob, tshuaj khomob thiab phais, thiab ua rau cov ntshav rheology zoo li qub. Cov khoom xyaw no muaj kev tiv thaiv zoo thiab tiv thaiv kab mob qog noj ntshav, tuaj yeem txhim kho tib neeg kev ua haujlwm thiab kev tiv thaiv kab mob, thiab muaj kev cuam tshuam tseem ceeb hauv kev ua ke nrog kev phais thiab kev kho hluav taws xob thiab tshuaj khomob.

Rg 5

Rg5 tuaj yeem ua rau apoptosis ntawm ntau cov qog hlwb. Rg5 muab rho tawm los ntawm nplua dub ginseng tau raug txheeb xyuas hauv tib neeg lub mis hlwb. Rg5 tseem tuaj yeem ua rau apoptosis thiab DNA puas nyob rau hauv ntau yam qog nqaij hlav qog noj ntshav. Aseries ntawm kev sim hauv vitro tau lees paub tias ginsenoside Rg5 muaj kev cuam tshuam rau cov qog nqaij hlav hauv plab.

Rh3

Ginsenoside Rh3 tuaj yeem cuam tshuam kev loj hlob ntawm tib neeg cov kab mob qog noj ntshav SW480 thiab induce apoptosis, thiab cov nyhuv yog koob tshuaj thiab nyob ntawm lub sijhawm.

aPPD

20 (S) - Protopanaxadiol (aPPD) yog ib qho khoom muaj txiaj ntsig nrog cov tshuaj ua tau zoo uas tsim los ntawm ginsenosides tom qab desugar metabolism thiab ua kom lub plab zom mov, thiab muaj ntau yam kev tiv thaiv qog noj ntshav. Nyob rau hauv xyoo tas los no, William Jia tshawb fawb pab pawg ntawm University ofBritish Columbia tau ua ntau txoj kev tshawb fawb txog kev tiv thaiv qog nqaij hlav ntawm aPPD hauv vivo thiab hauv vitro, thiab pom tias nws muaj cov tshuaj pharmacological dual. Ntawm ib sab, nws tuaj yeem tua cov qog hlwb ncaj qha thiab txhawb lawv cov apoptosis; Ntawm qhov tod tes, nws tuaj yeem tiv thaiv cov neurons los ntawm cov tshuaj cytotoxic.
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Dab tsi yog Qhov Kev Pabcuam NtawmGinsenosides?

Cov txiaj ntsig ntawm ginsenosides, cov tshuaj nquag muaj nyob hauv ginseng, muaj ntau yam thiab tau ua raws li kev tshawb fawb dav dav. Qee qhov txiaj ntsig zoo ntawm ginsenosides suav nrog:

1. Kev Paub Txog Kev Ua Haujlwm: Ginsenosides tau kawm txog lawv lub peev xwm los txhawb kev paub txog kev ua haujlwm, suav nrog kev nco, ua kom pom tseeb, thiab lub hlwb kom meej meej.

2. Zog thiab Vitality: Ginsenosides ntseeg tau tias muaj cov khoom siv adaptogenic, uas pab txhawb lub zog, txo qhov qaug zog, thiab txhawb kev loj hlob ntawm tag nrho.

3. Kev Txhawb Kev Tiv Thaiv Kab Mob: Qee qhov kev tshawb fawb qhia tias ginsenosides muaj kev tiv thaiv kab mob tiv thaiv kab mob, muaj peev xwm txhawb kev tiv thaiv kab mob.

4. Kev Tswj Kev Nyuaj Siab: Ginsenosides suav hais tias yog adaptogens, uas txhais tau hais tias lawv pab lub cev hloov mus rau kev ntxhov siab thiab txhawb kev noj qab haus huv.

5. Kev Noj Qab Haus Huv Kev Noj Qab Haus Huv: Qee cov kev tshawb fawb tau tshawb fawb txog qhov muaj peev xwm ntawm ginsenosides hauv kev txhawb nqa kev noj qab haus huv ntawm cov hlab plawv, nrog rau lawv cov teebmeem ntawm cov ntshav siab thiab kev ncig.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov txiaj ntsig tshwj xeeb ntawm ginsenosides sib txawv nyob ntawm seb hom ginseng thiab muaj pes tsawg leeg ntawm ginsenosides tam sim no. Raws li nrog rau cov khoom ntxiv lossis cov khoom ntuj tsim, nws raug nquahu kom sab laj nrog tus kws kho mob rau cov lus qhia tus kheej txog kev siv ginsenosides rau kev txhawj xeeb txog kev noj qab haus huv.

Dab tsi yog Daim Ntawv Thov ntawm Ginsenosides?

Ginsenosides muaj ntau yam kev siv peev xwm vim lawv cov khoom siv tshuaj sib txawv. Qee qhov kev siv ntawm ginsenosides suav nrog:

1. Cov tshuaj tsoos: Ginsenosides tau siv rau ntau pua xyoo hauv cov tshuaj tsoos, tshwj xeeb tshaj yog nyob rau sab hnub tuaj Asia, rau lawv cov khoom ua kom muaj zog thiab txhawb kev noj qab haus huv.

2. Cov Khoom Ntxiv: Ginsenosides feem ntau yog siv los ua cov khoom xyaw nquag hauv cov khoom noj khoom haus thiab tshuaj ntsuab npaj los txhawb kev paub txog kev ua haujlwm, qib zog, thiab kev noj qab haus huv tag nrho.

3. Pharmaceuticals: Kev tshawb fawb txog kev siv tshuaj kho mob uas muaj peev xwm ntawm ginsenosides tau ua rau lawv siv hauv cov khoom siv tshuaj, tshwj xeeb tshaj yog nyob rau hauv kev tsim cov tshuaj rau tej yam kev mob xws li kev txawj ntse poob, qaug zog, thiab kev ntxhov siab.

4. Tshuaj pleev ib ce: Ginsenosides kuj tseem siv rau hauv kev lag luam tshuaj pleev ib ce rau lawv cov txiaj ntsig zoo ntawm daim tawv nqaij, nrog rau kev tiv thaiv kev laus thiab antioxidant zog.

5. Khoom noj khoom haus thiab dej haus muaj nuj nqi: Ginsenosides tau muab tso rau hauv ntau yam khoom noj thiab dej haus, xws li dej qab zib thiab tshuaj tonics, los muab cov txiaj ntsig zoo rau kev noj qab haus huv.

Dab tsi yog Qhov Teeb Meem NtawmGinsenosides?

Ginsenosides feem ntau suav hais tias muaj kev nyab xeeb thaum siv cov koob tshuaj uas tsim nyog, tab sis zoo li txhua yam bioactive compound, lawv yuav muaj peev xwm tshwm sim, tshwj xeeb tshaj yog thaum noj ntau heev. Qee qhov kev mob tshwm sim ntawm ginsenosides tuaj yeem suav nrog:

1. Insomnia: Kev siv ntau ntawm ginsenosides tuaj yeem ua rau overstimulation, ua rau nyuaj rau pw tsaug zog lossis pw tsaug zog.

2. Cov teeb meem digestive: Qee tus neeg yuav muaj kev tsis xis nyob hauv plab, xws li xeev siab, raws plab, lossis mob plab, thaum noj cov tshuaj ginsenosides ntau.

3. Mob ntshav siab: Muaj tsawg zaus, kev noj ginsenosides ntau dhau tuaj yeem ua rau ntshav siab.

4. Kev Ua xua: Txawm tias tsis tshua muaj tshwm sim, qee tus neeg yuav ua xua rau ginsenosides, ua rau muaj cov tsos mob xws li pob khaus, khaus, lossis ua pa nyuaj.

5. Cov teebmeem Hormonal: Ginsenosides tej zaum yuav muaj cov tshuaj hormonal me me, thiab qee zaum, lawv yuav cuam tshuam nrog cov tshuaj hormones los yog tej yam kev mob.

Nws yog ib qho tseem ceeb kom nco ntsoov tias cov kev mob tshwm sim ntawm ginsenosides tuaj yeem sib txawv nyob ntawm tus neeg, hom tshwj xeeb ntawm ginseng, thiab ntau npaum li cas. Raws li nrog rau cov khoom siv ntxiv lossis cov khoom ntuj tsim, nws raug nquahu kom sab laj nrog kws kho mob ua ntej siv ginsenosides, tshwj xeeb tshaj yog rau cov neeg muaj mob hauv qab lossis cov tshuaj noj.

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Cov lus nug ntsig txog koj tuaj yeem txaus siab rau:

Leej twg yuav tsum tsis txhob noj ginseng?

Qee tus neeg yuav tsum tau ceev faj lossis tsis txhob noj ginseng, suav nrog:

1. Cov poj niam cev xeeb tub lossis pub niam mis: Kev nyab xeeb ntawm ginseng thaum cev xeeb tub thiab pub niam mis tsis tau kawm ntau, yog li nws feem ntau pom zoo kom tsis txhob siv nws thaum lub sijhawm no.

2. Cov tib neeg uas muaj kab mob autoimmune: Ginseng tuaj yeem ua rau lub cev tiv thaiv kab mob, uas tuaj yeem ua rau cov kab mob autoimmune hnyav dua. Nws raug nquahu rau cov tib neeg uas muaj kab mob autoimmune mus ntsib kws kho mob ua ntej siv ginseng.

3. Cov neeg uas muaj ntshav tsis txaus: Ginseng tej zaum yuav muaj cov tshuaj tiv thaiv kab mob me me, yog li cov tib neeg uas muaj ntshav tsis txaus lossis cov neeg noj cov tshuaj ntshav ntshav yuav tsum siv ginseng ceev faj thiab raws li kev qhia ntawm tus kws kho mob.

4. Cov tib neeg uas muaj cov kab mob hormone-rhiab heev: Vim tias muaj peev xwm hormonal cuam tshuam ntawm ginseng, cov tib neeg uas muaj cov tshuaj hormone-rhiab heev xws li mob qog noj ntshav, uterine fibroids, lossis endometriosis yuav tsum sab laj nrog kws kho mob ua ntej siv ginseng.

5. Cov neeg uas muaj Insomnia los yog ntxhov siab vim: Ginseng tej zaum yuav muaj stimulating teebmeem, yog li cov neeg uas muaj insomnia los yog ntxhov siab vim yuav tsum tau ceev faj thaum siv ginseng, tshwj xeeb tshaj yog nyob rau hauv cov koob tshuaj ntau.

Puas yog ginsenosides steroids?

Ginsenosides tsis yog steroids. Lawv yog ib pawg ntawm natural compounds pom nyob rau hauv cov nroj tsuag ginseng. Thaum ginsenosides tuaj yeem muaj ntau yam txiaj ntsig kev noj qab haus huv, lawv yog cov qauv thiab ua haujlwm txawv ntawm cov tshuaj steroids. Steroids yog ib chav kawm ntawm cov tshuaj hormones thiab lipids uas ua lub luag haujlwm tseem ceeb hauv lub cev metabolism, lub cev tsis muaj zog, thiab lwm yam txheej txheem physiological. Nyob rau hauv sib piv, ginsenosides yog saponins, ib hom glycoside compound, thiab lawv paub txog lawv cov adaptogenic thiab kev noj qab haus huv zog. 

Qhov twg ginseng muaj qhov siab tshaj plawsginsenosides muaj?

Hom ginseng uas muaj cov ntsiab lus ginsenoside siab tshaj plaws yog Panax ginseng, tseem hu ua Asian lossis Korean ginseng. Hom ginseng no paub txog nws cov nplua nuj concentration ntawm ginsenosides, uas yog cov bioactive compounds lub luag hauj lwm rau ntau yam ntawm cov nroj tsuag cov txiaj ntsig kev noj qab haus huv. Panax ginseng muaj nuj nqis heev hauv cov tshuaj ib txwm siv thiab feem ntau yog siv rau nws cov peev xwm adaptogenic thiab revitalizing zog. Thaum nrhiav cov khoom lag luam ginseng nrog cov ntsiab lus ginsenoside siab, Panax ginseng yog qhov kev xaiv nrov.

Puas yog noj ginseng txhua hnub?

Nws feem ntau suav hais tias muaj kev nyab xeeb rau cov neeg feem coob noj ginseng txhua hnub rau lub sijhawm luv luv. Txawm li cas los xij, kev siv ginseng ntev ntev tuaj yeem ua rau muaj kev phiv los yog cuam tshuam nrog cov tshuaj. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tau siv ginseng raws li kev taw qhia ntawm tus kws kho mob, tshwj xeeb tshaj yog tias koj npaj yuav noj nws txhua hnub rau lub sijhawm ntev. Kev sab laj nrog tus kws kho mob tuaj yeem pab xyuas kom meej tias ginseng tsim nyog rau koj tus kheej xav tau kev noj qab haus huv thiab nws tsis cuam tshuam nrog cov tshuaj lossis cov xwm txheej ua ntej.

Puas yog ginseng nce testosterone?

Ginseng tau raug qhia tias muaj peev xwm cuam tshuam rau qib testosterone, txawm hais tias cov pov thawj tsis yog qhov tseeb. Qee cov kev tshawb fawb tau qhia tias ginseng tuaj yeem muaj kev cuam tshuam me me ntawm qib testosterone, uas muaj peev xwm los ntawm kev txhawb nqa cov txheej txheem koom nrog hauv kev tsim cov testosterone. Txawm li cas los xij, xav tau kev tshawb fawb ntxiv kom nkag siab txog qhov ntawm ginseng lub zog ntawm testosterone.

Ginseng ua dab tsi rau poj niam cov tshuaj hormones?

Ginseng tej zaum yuav muaj feem cuam tshuam rau poj niam cov tshuaj hormones, txawm hais tias kev tshawb fawb hauv cheeb tsam no tsis yog tag nrho. Qee qhov kev tshawb fawb tau qhia tias ginseng tuaj yeem muaj cov khoom hloov pauv uas tuaj yeem pab txhawb kev sib npaug ntawm cov poj niam, tshwj xeeb tshaj yog thaum lub sij hawm muaj kev ntxhov siab lossis kev hloov pauv hormonal. Tsis tas li ntawd, ginseng tau tshawb fawb txog nws cov txiaj ntsig zoo hauv kev hais txog cov tsos mob cuam tshuam nrog kev mob ntshav qab zib, xws li kub kub thiab hloov mus ob peb vas.


Post lub sij hawm: Sep-12-2024