Dab tsi yogAzelaic Acid?
Azelaic Acid yog ib txwm tshwm sim dicarboxylic acid uas tau siv dav hauv kev tu tawv nqaij thiab kho ntau yam ntawm daim tawv nqaij. Nws muaj cov tshuaj tua kab mob, tiv thaiv kab mob thiab keratin tswj cov khoom thiab feem ntau siv los kho cov teeb meem ntawm daim tawv nqaij xws li pob txuv, rosacea thiab hyperpigmentation.
Physical and Chemical Properties of Azelaic Acid
1. Chemical Structure thiab Properties
Chemical Structure
Lub npe tshuaj: Azelaic Acid
Cov roj formula: C9H16O4
Molecular Luj: 188.22 g / mol
Structure: Azelaic acid yog ib qho ncaj-chain saturated dicarboxylic acid.
2. Lub cev muaj zog
Cov tsos mob: Azelaic acid feem ntau tshwm li cov hmoov dawb crystalline.
Solubility: Nws yog me ntsis soluble hauv dej tab sis ntau soluble hauv cov kuab tshuaj organic xws li ethanol thiab propylene glycol.
Melting Point: Kwv yees li 106-108 ° C (223-226 ° F).
3. Mechanism of Action
Antibacterial: Azelaic acid inhibits kev loj hlob ntawm cov kab mob, tshwj xeeb tshaj yog Propionibacterium acnes, uas yog ib qho tseem ceeb contributor rau pob txuv.
Anti-Inflammatory: Nws txo qhov mob los ntawm inhibiting zus tau tej cov pro-inflammatory cytokines.
Keratinization Regulation: Azelaic acid pab normalize lub cev ntawm cov tawv nqaij tuag, tiv thaiv cov pores thiab tsim ntawm comedones.
Tyrosinase Inhibition: Nws inhibits enzyme tyrosinase, uas koom nrog hauv kev tsim melanin, yog li pab txo qis hyperpigmentation thiab melasma.
Dab tsi yog Cov txiaj ntsig ntawmAzelaic Acid?
Azelaic Acid yog ntau yam dicarboxylic acid dav siv hauv kev tu tawv nqaij thiab kho ntau yam teeb meem ntawm daim tawv nqaij. Nov yog cov txiaj ntsig tseem ceeb ntawm azelaic acid:
1. Kho pob txuv
- Antibacterial effect: Azelaic acid tuaj yeem cuam tshuam kev loj hlob ntawm Propionibacterium acnes thiab Staphylococcus aureus, uas yog cov kab mob tseem ceeb ntawm pob txuv.
- Anti-inflammatory effect: Nws tuaj yeem txo qhov inflammatory teb ntawm daim tawv nqaij thiab txo qhov liab, o thiab mob.
- Keratin Regulating: Azelaic acid pab normalize lub cev ntawm cov tawv nqaij tuag, tiv thaiv cov pores thiab pob txuv tsim.
2. Kev kho mob ntawm Rosacea
- Txo Redness: Azelaic acid zoo txo qhov liab thiab mob txuam nrog rosacea.
- Antibacterial Effects: Nws inhibits kev loj hlob ntawm cov kab mob rosacea thiab txo cov kab mob ntawm daim tawv nqaij.
3. Txhim kho pigmentation
- Cov nyhuv Whitening: Azelaic acid pab txo cov pigmentation thiab chloasma los ntawm inhibiting cov haujlwm ntawm tyrosinase thiab txo melanin ntau lawm.
- Txawm tias tawv nqaij: kev siv tsis tu ncua ua rau cov tawv nqaij ntau dua, txo cov pob qij txha thiab cov pigmentation tsis sib xws.
4. Antioxidant nyhuv
- Neutralizing Free Radicals: Azelaic acid muaj cov khoom antioxidant uas ua rau cov dawb radicals txo qis oxidative kev nyuaj siab rau ntawm daim tawv nqaij.
- Los tiv thaiv kev laus: Los ntawm kev txo cov dawb radical puas, Azelaic acid pab qeeb ntawm daim tawv nqaij laus thiab txo cov tsos ntawm cov kab zoo thiab wrinkles.
5. Kev kho mob tom qab mob Pigmentation (PIH)
- Txo Pigmentation: Azelaic acid zoo kho tom qab mob hyperpigmentation, uas feem ntau tshwm sim tom qab pob txuv lossis lwm yam mob ntawm daim tawv nqaij.
- Txhawb kev kho daim tawv nqaij: Nws txhawb kev tsim kho thiab kho ntawm daim tawv nqaij thiab ua kom lub fading ntawm pigmentation.
6. Haum rau cov tawv nqaij rhiab heev
- Yooj yim thiab tsis ua rau khaus: Azelaic acid feem ntau ua tau zoo thiab haum rau cov tawv nqaij rhiab heev.
- Noncomedogenic: Nws tsis clog pores thiab haum rau pob txuv-nrhiav tawv nqaij.
7. Kho lwm yam kab mob ntawm daim tawv nqaij
- Keratosis Pilaris: Azelaic acid tuaj yeem pab txo cov tawv nqaij tawv, tawv nqaij cuam tshuam nrog Keratosis Pilaris.
- Lwm yam kab mob ntawm daim tawv nqaij: Nws kuj muaj qee yam kev kho mob rau lwm yam kab mob ntawm daim tawv nqaij xws li eczema thiab psoriasis.
Dab tsi yog Cov Ntawv Thov NtawmAzelaic Acid?
1. Kho pob txuv: tshuaj pleev
- Acne Creams thiab Gels: Azelaic acid feem ntau yog siv rau hauv cov tshuaj pleev ib ce los kho pob txuv me me mus rau nruab nrab. Nws pab txo tus naj npawb ntawm pob txuv qhov txhab thiab tiv thaiv kev tsim cov tshiab.
- Kev Kho Mob Ua Ke: Feem ntau siv nrog rau lwm yam kev kho pob txuv xws li benzoyl peroxide lossis retinoic acid los txhim kho kev ua tau zoo.
2. Kev kho mob Rosacea: Kev npaj tshuaj tiv thaiv
- Rosacea Creams thiab Gels: Azelaic acid zoo txo qhov liab thiab mob txuam nrog rosacea thiab feem ntau siv rau hauv cov tshuaj pleev ib ce tshwj xeeb ntawm rosacea.
- Kev Tswj Lub Sij Hawm Ntev: Tsim nyog rau kev tswj xyuas mus sij hawm ntev ntawm rosacea, pab tswj lub xeev ruaj khov ntawm daim tawv nqaij.
3. Txhim kho pigmentation: Cov khoom ua kom dawb
- Brightening Creams thiab Serums: Azelaic acid pab txo cov pigmentation thiab melasma los ntawm inhibiting tyrosinase kev ua si thiab txo melanin ntau lawm.
- Txawm tias tawv nqaij: kev siv tsis tu ncua ua rau cov tawv nqaij ntau dua, txo cov pob qij txha thiab cov pigmentation tsis sib xws.
4. Antioxidant thiab anti-aging: Antioxidant khoom tu tawv nqaijs
- Anti-Aging Creams thiab Serums: Cov tshuaj antioxidant ntawm Azelaic acid ua rau nws muaj cov khoom tseem ceeb hauv cov khoom siv kho tawv nqaij tiv thaiv kev laus, pab txo cov dawb radical puas rau ntawm daim tawv nqaij thiab ua kom tawv nqaij laus.
- Kev tu tawv nqaij txhua hnub: tsim nyog rau kev tu tawv nqaij txhua hnub, muab kev tiv thaiv antioxidant thiab ua kom tawv nqaij noj qab haus huv.
5. Kev kho mob tom qab mob Pigmentation (PIH): Pigmentation Repair Products
- Kho Creams thiab Serums: Azelaic acid muaj txiaj ntsig zoo hauv kev kho mob tom qab mob hyperpigmentation thiab feem ntau siv los kho cov tshuaj pleev thiab cov tshuaj pleev ib ce los pab ua kom poob ntawm hyperpigmentation.
- Kho daim tawv nqaij: Txhawb kev tsim dua tshiab thiab kho cov hlwb ntawm daim tawv nqaij thiab ua kom cov pigmentation fading.
6. Kho lwm yam kab mob ntawm daim tawv nqaij
Keratosis pilaris
- keratin txias cov khoom: Azelaic acid tuaj yeem pab txo cov tawv nqaij tawv, tawv nqaij cuam tshuam nrog keratosis pilaris thiab feem ntau siv rau hauv cov khoom siv keratin txias.
- Daim tawv nqaij Smoothing: Txhawb cov tawv nqaij smoothness thiab softness, txhim kho daim tawv nqaij zoo nkauj.
Lwm yam kab mob ntawm daim tawv nqaij
- Eczema thiab Psoriasis: Azelaic acid kuj muaj qee yam kev kho mob rau lwm yam kab mob ntawm daim tawv nqaij xws li eczema thiab psoriasis, thiab feem ntau siv rau hauv kev npaj tshuaj pleev ib ce.
7. Kev tu tawv taub hau: Cov khoom siv tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob
- Cov khoom siv tawv taub hau: Azelaic acid cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob ua rau nws tsim nyog siv cov khoom tu tawv taub hau los pab txo cov tawv taub hau mob thiab kis kab mob.
- Scalp Health: Txhawb nqa tawv taub hau kev noj qab haus huv thiab txo cov dandruff thiab khaus khaus.
Cov lus nug ntsig txog koj tuaj yeem txaus siab rau:
Ua liazelaic acidmuaj kev phiv?
Azelaic acid tuaj yeem muaj kev phiv, txawm hais tias nws feem ntau ua tau zoo los ntawm cov neeg feem coob. Cov kev mob tshwm sim feem ntau yog me me thiab zoo li yuav ploj mus nrog kev siv txuas ntxiv. Nov yog qee qhov kev mob tshwm sim thiab kev xav txog:
1. Tej yam tshwm sim
Daim tawv nqaij khaus
- Cov tsos mob: khaus khaus, liab, khaus, lossis kub hnyiab ntawm qhov chaw thov.
- Kev tswj hwm: Cov tsos mob no feem ntau txo qis thaum koj cov tawv nqaij hloov kho. Yog tias khaus khaus tshwm sim, koj yuav tsum tau txo qhov zaus ntawm daim ntawv thov lossis nrog tus kws kho mob tham.
Dryness thiab Peeling
- Cov tsos mob: dryness, flaking, los yog tev ntawm daim tawv nqaij.
- Kev tswj hwm: Siv cov moisturizer maj mam txo cov dryness thiab tswj cov tawv nqaij hydration.
2. Cov teebmeem tshwm sim tsawg dua
Hypersensitivity Reactions
- Cov tsos mob: khaus khaus khaus, pob khaus, o, lossis khaus khaus.
- Kev tswj hwm: Tsis txhob siv tam sim ntawd thiab sab laj nrog kws kho mob yog tias koj pom muaj cov tsos mob ntawm kev tsis haum tshuaj.
Ua kom Sun Sensitivity
- Cov tsos mob: nce rhiab heev rau lub hnub ci, ua rau tshav ntuj los yog lub hnub puas tsuaj.
- Kev tswj hwm: Siv cov tshuaj pleev thaiv hnub dav dav txhua hnub thiab tsis txhob raug tshav ntuj ntev.
3. Tsis tshua muaj tshwm sim
Cov tawv nqaij tawv heev
- Cov tsos mob: liab liab, hlwv, los yog tawv heev.
- Kev tswj hwm: Tso tseg kev siv thiab nrhiav cov lus qhia kho mob yog tias koj muaj kev cuam tshuam ntawm daim tawv nqaij hnyav.
4. Kev ceev faj thiab kev txiav txim siab
Patch Test
- Cov Lus Pom Zoo: Ua ntej siv azelaic acid, ua qhov ntsuas patch rau ntawm thaj chaw me me ntawm daim tawv nqaij txhawm rau txheeb xyuas qhov tsis zoo tshwm sim.
Kev Taw Qhia Ntxiv
- Cov lus pom zoo: Yog tias koj tshiab rau azelaic acid, pib nrog qis qis thiab maj mam nce zaus ntawm daim ntawv thov kom tso cai rau koj cov tawv nqaij kho.
Kev sab laj
- Kev Pom Zoo: Nrog rau tus kws kho mob dermatologist lossis tus kws kho mob ua ntej pib azelaic acid, tshwj xeeb tshaj yog tias koj muaj tawv nqaij rhiab lossis siv lwm cov khoom siv tawv nqaij.
5. Cov neeg tshwj xeeb
Cev xeeb tub thiab pub niam mis
- Kev nyab xeeb: Azelaic acid feem ntau suav tias muaj kev nyab xeeb rau kev siv thaum cev xeeb tub thiab pub niam mis, tab sis nws yog qhov zoo tshaj plaws los sab laj tus kws kho mob ua ntej pib kho tshiab.
Daim tawv nqaij rhiab heev
- Kev txiav txim siab: Cov neeg uas muaj tawv nqaij rhiab yuav tsum siv azelaic acid nrog ceev faj thiab yuav tau txais txiaj ntsig los ntawm cov qauv tsim los rau cov tawv nqaij rhiab heev.
Nws yuav siv sij hawm ntev npaum li cas thiaj pom cov txiaj ntsig ntawmazelaic acid?
Lub sijhawm nws siv los saib cov txiaj ntsig ntawm azelaic acid tuaj yeem sib txawv, tab sis kev txhim kho thawj zaug feem ntau pom nyob rau hauv 2 mus rau 4 lub lis piam rau pob txuv, 4 mus rau 6 lub lis piam rau rosacea, thiab 4 mus rau 8 lub lis piam rau hyperpigmentation thiab melasma. Cov txiaj ntsig tseem ceeb tshaj plaws feem ntau tshwm sim tom qab 8 mus rau 12 lub lis piam ntawm kev siv zoo ib yam. Cov yam ntxwv xws li cov concentration ntawm azelaic acid, zaus ntawm daim ntawv thov, tus yam ntxwv ntawm daim tawv nqaij, thiab qhov mob hnyav ntawm kev kho mob tuaj yeem cuam tshuam rau kev ua tau zoo thiab ceev ntawm cov txiaj ntsig. Kev siv tsis tu ncua thiab zoo ib yam, nrog rau kev ua kom tawv nqaij ntxiv, tuaj yeem pab ua tiav cov txiaj ntsig zoo tshaj plaws.
Cov yam ntxwv cuam tshuam rau cov txiaj ntsig
Concentration ntawm Azelaic Acid
Kev Cuam Tshuam Ntau Dua: Cov khoom uas muaj ntau dua ntawm azelaic acid (piv txwv li, 15% mus rau 20%) tuaj yeem tsim cov txiaj ntsig sai dua thiab pom ntau dua.
Lower Concentrations: Cov khoom uas muaj cov concentrations qis dua yuav siv sij hawm ntev dua los qhia pom cov teebmeem.
Kev siv ntau zaus
Kev Siv Ib Leeg: Siv azelaic acid raws li qhia, feem ntau ib zaug lossis ob zaug ib hnub, tuaj yeem txhim kho cov txiaj ntsig thiab ua kom tau txais txiaj ntsig.
Kev siv tsis raug: Cov ntawv thov tsis tu ncua tuaj yeem ncua qhov pom kev cuam tshuam thiab txo cov txiaj ntsig tag nrho.
Tus cwj pwm ntawm daim tawv nqaij
Hom tawv nqaij: Ib hom tawv nqaij thiab tus mob tuaj yeem cuam tshuam sai npaum li cas pom tau. Piv txwv li, cov tib neeg uas muaj cov tawv nqaij sib zog tuaj yeem pom cov txiaj ntsig sai dua piv rau cov neeg uas muaj cov tawv nqaij tawv dua.
Kev mob hnyav: Qhov mob hnyav ntawm daim tawv nqaij raug kho kuj tuaj yeem cuam tshuam rau lub sijhawm nws yuav siv los pom cov txiaj ntsig. Cov mob me tuaj yeem teb sai dua qhov mob hnyav dua.
Thaum twg siv azelaic acid, sawv ntxov lossis hmo ntuj?
Azelaic acid tuaj yeem siv tau ob qho tib si thaum sawv ntxov thiab yav tsaus ntuj, nyob ntawm koj cov kev tu tawv nqaij thiab kev xav tau tshwj xeeb. Yog tias siv thaum sawv ntxov, ib txwm ua raws li tshuaj pleev thaiv hnub los tiv thaiv koj cov tawv nqaij los ntawm UV puas. Kev siv nws thaum hmo ntuj tuaj yeem txhim kho daim tawv nqaij thiab txo qis kev cuam tshuam nrog lwm cov khoom xyaw nquag. Rau cov txiaj ntsig siab tshaj plaws, qee tus neeg xaiv siv azelaic acid thaum sawv ntxov thiab yav tsaus ntuj, tab sis nws yog ib qho tseem ceeb los saib xyuas koj cov tawv nqaij cov lus teb thiab kho kom haum. Ib txwm siv azelaic acid tom qab ntxuav thiab ua ntej moisturizing, thiab xav txog seb nws haum rau koj cov tawv nqaij tag nrho kom ua tiav cov txiaj ntsig zoo tshaj plaws.
Dab tsi los sib xyaw nrogazelaic acid?
Azelaic acid yog ntau yam thiab feem ntau muaj kev tiv thaiv tawv nqaij zoo, tab sis nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias nws cuam tshuam nrog lwm cov khoom xyaw hauv koj cov kev tu tawv nqaij. Kev sib xyaw qee yam khoom xyaw tuaj yeem ua rau khaus, txo qis, lossis lwm yam tsis xav tau. Nov yog qee cov lus qhia txog yam tsis txhob sib xyaw nrog azelaic acid:
1. Muaj zog Exfoliants
Alpha Hydroxy Acids (AHAs)
- Piv txwv li: Glycolic acid, lactic acid, mandelic acid.
- Yog vim li cas: Kev sib xyaw azelaic acid nrog AHAs muaj zog tuaj yeem ua rau muaj kev pheej hmoo ntawm khaus, liab, thiab tev. Ob leeg yog exfoliants, thiab siv lawv ua ke tuaj yeem hnyav heev rau daim tawv nqaij.
Beta Hydroxy Acids (BHAs)
- Piv txwv li: salicylic acid.
- Vim li cas: Zoo ib yam li AHAs, BHAs kuj yog exfoliants. Siv lawv ua ke nrog azelaic acid tuaj yeem ua rau over-exfoliation thiab tawv nqaij rhiab heev.
2. Retinoids
- Piv txwv li: Retinol, Retinaldehyde, Tretinoin, Adapalene.
- Yog vim li cas: Retinoids yog cov khoom xyaw muaj zog uas tuaj yeem ua rau dryness, tev, thiab khaus khaus, tshwj xeeb tshaj yog thaum xub thawj. Kev sib xyaw ua ke nrog azelaic acid tuaj yeem ua rau cov kev mob tshwm sim hnyav dua.
3. Benzoyl Peroxide
Yog vim li cas
- Kev khaus khaus: Benzoyl peroxide yog cov khoom siv pob txuv uas muaj zog uas tuaj yeem ua rau qhuav thiab khaus khaus. Siv nws nrog azelaic acid tuaj yeem ua rau muaj kev pheej hmoo ntawm daim tawv nqaij khaus.
- Txo Kev Ua Tau Zoo: Benzoyl peroxide tuaj yeem oxidize lwm cov khoom xyaw, uas yuav txo tau lawv cov txiaj ntsig.
4. Vitamin C (Ascorbic Acid)
Yog vim li cas
- Qib pH: Vitamin C (ascorbic acid) yuav tsum muaj pH qis kom ua tau zoo, thaum azelaic acid ua haujlwm zoo tshaj ntawm pH siab dua me ntsis. Kev siv lawv ua ke tuaj yeem cuam tshuam qhov kev ua tau zoo ntawm ob qho khoom xyaw.
- Irritation: Kev sib xyaw ob cov khoom xyaw muaj zog tuaj yeem ua rau muaj kev pheej hmoo ntawm kev khaus, tshwj xeeb tshaj yog rau cov tawv nqaij rhiab heev.
5. Niacinamide
Yog vim li cas
- Muaj peev xwm sib cuam tshuam: Thaum niacinamide feem ntau ua tau zoo thiab tuaj yeem siv nrog ntau cov khoom xyaw nquag, qee tus neeg yuav muaj kev khaus khaus thaum sib txuas nrog azelaic acid. Qhov no tsis yog txoj cai thoob ntiaj teb, tab sis nws yog ib yam uas yuav tsum tau paub txog.
6. Lwm yam muaj zog ua haujlwm
Piv txwv
- Hydroquinone, Kojic Acid, thiab lwm yam tawv nqaij-lightening agents.
- Yog vim li cas: Kev sib xyaw ua ke ntau lub zog ua haujlwm tsom rau kev kho mob hyperpigmentation tuaj yeem ua rau muaj kev pheej hmoo ntawm kev khaus thiab tsis tas yuav txhim kho kev ua tau zoo.
Yuav koom ua ke li casAzelaic AcidSafely:
Hloov Use
- Lub tswv yim: Yog tias koj xav siv azelaic acid nrog rau lwm cov tshuaj muaj zog, xav txog kev hloov pauv lawv siv. Piv txwv li, siv azelaic acid thaum sawv ntxov thiab retinoids lossis AHAs / BHAs thaum hmo ntuj.
Patch Test
- Cov lus pom zoo: Ib txwm ua qhov ntsuas patch thaum qhia cov khoom muaj txiaj ntsig tshiab rau koj lub sijhawm los kuaj xyuas qhov tsis zoo tshwm sim.
Pib maj mam
- Lub tswv yim: Qhia azelaic acid maj mam, pib nrog qis qis thiab nce zaus raws li koj cov tawv nqaij ua siab ntev.
Nrog rau tus kws kho mob Dermatologist
- Kev Pom Zoo: Yog tias koj tsis paub meej txog yuav ua li cas koom nrog azelaic acid rau hauv koj lub sijhawm, nrog tus kws kho mob dermatologist rau cov lus qhia ntawm tus kheej.
Post lub sij hawm: Sep-21-2024
