Dab tsi yogAzelaic acid?
Azelaic acid yog ib txwm muaj tshwm sim dicarboxylic acid uas tau siv dav hauv kev tu tawv nqaij thiab kho ntau yam ntawm daim tawv nqaij. Nws muaj cov tshuaj tua kabmob, tiv thaiv kab mob thiab feem ntau siv los kho cov teeb meem tawv nqaij xws li pob txuv, rosacea thiab hyperpigmentation.
Lub cev thiab tshuaj lom neeg ntawm azelaic acid
1. Tshuaj Txhuam Cov Qauv thiab Khoom
Cov Qauv Tshuaj
Tshuaj Lom Zem Lub Npe: Azelaic Acid
Tshuaj mis: C9H16o4
Molecular hnyav: 188.22 g / mol
Cov qauv: Azelaic acid yog ib txoj kev ncaj-saw satentated dicarboxylic acid.
2.Praysical Khoom
Zog: Azelaic acid feem ntau tshwm sim ua hmoov dawb dawb.
Solubility: Nws yog me ntsis soluble hauv dej tab sis ntau soluble hauv cov kuab tshuaj muaj zog zoo li ethanol thiab propylene glycol.
Melting taw tes: kwv yees li 106-108 ° C (223-226 ° F).
3. Mechanism ntawm Kev Ua
Cov tshuaj tua kab mob: Azelaic acid inibits kev loj hlob ntawm cov kab mob, tshwj xeeb yog propionibacterium acnes, uas yog tus yuam sij pab ua pob txuv.
Anti-inflammatory: nws txo qhov o los ntawm kev tiv thaiv cov khoom tsim ntawm pro-inflammatory cytokines.
Keratinization txoj cai: Azelaic acid pab ua kom zoo ntawm cov tawv nqaij tuag, tiv thaiv kom thaiv cov hws thiab kev tsim cov comedones.
Tyrosinase Inhibition: nws inhibits lub enzyme tyrosinase, uas yog koom nrog hauv Melanin ntau lawm, yog li pab txo cov hyperpigmentation thiab melasma.
Dab tsi yog cov txiaj ntsig ntawmAzelaic acid?
Azelaic acid yog ib qho ntau yam dicarboxylic acid dav siv hauv kev tu tawv nqaij thiab kho cov teeb meem ntawm cov tawv nqaij. Ntawm no yog cov txiaj ntsig tseem ceeb ntawm azelaic acid:
1. Kho pob txuv
- Cov nyhuv tua hluav taws xob: Azelaic acid tuaj yeem ua rau muaj kev loj hlob ntawm cov propionibacterium actus thiab Staphylococcus aureus thiab staphyric cov kab mob ntawm pob txuv.
- Anti-inflammatory nyhuv: nws tuaj yeem txo cov khoom tawv nqaij ntawm cov tawv nqaij thiab txo qis, o thiab mob.
- Keratin Kev tswj hwm: Azelaic acid pab ua kom zoo ntawm cov tawv nqaij uas tuag, tiv thaiv kom thaiv cov hws thiab ua pob txuv.
2. Kev kho mob Rosacea
- Txo cov nyiaj liab liab: azelaic acid zoo txo qhov liab thiab o muaj feem nrog rosacea.
- Cov nyhuv tua kab mob: nws inhibits qhov kev loj hlob ntawm rosacea-cuam tshuam cov kab mob thiab txo qhov kev pheej hmoo ntawm daim tawv nqaij.
3. Txhim Kho Cov Pirmentation
- Cov nyhuv ntxuav hniav dawb: Azelaic acid pab txo cov xim thiab cov leeg ntshav los ntawm kev ua haujlwm ntawm Tyrosinase thiab txo cov melanin ntau lawm.
- Txawm tias cov tawv nqaij Tone: siv cov txiaj ntsig tsis tu ncua hauv cov tawv nqaij, txo cov xim tsaus nti thiab tsis sib xws thiab tsis sib xws.
4. Antioxidant nyhuv
- nruab nrab dawb radicals: Azelaic acid muaj cov tshuaj antioxidant uas neutralize dawb radicals thiab txo cov oxidative kev puas tsuaj rau daim tawv nqaij.
- Anti-art: los ntawm kev txo dawb radical puas tsuaj, azelaic acid pab qeeb cov kev laus me ntsis thiab txo cov tsos ntawm cov kab zoo thiab wrinkles.
5. Kev kho mob ntawm kev tshaj tawm-Inflammatory (PIH)
- Txo cov xim xim: Azelaic acid zoo nkauj tom qab-inflammatory hyperpigmentation, uas feem ntau tshwm sim tom qab pob txuv lossis lwm yam tawv nqaij mob.
- txhawb kev kho cov tawv nqaij: nws txhawb nqa kev tsim dua tshiab thiab kho cov tawv nqaij hlwb thiab nrawm fading ntawm pigmentation.
6. Haum rau rhiab tawv nqaij
- Kev maj thiab tsis-ua kom muaj zog: azelaic acid feem ntau yog ua kom muaj kev zam thiab haum rau cov tawv tawv rhiab.
- Uncomposenic: nws tsis clog pores thiab yog haum rau pob txuv-prone tawv nqaij.
7. Kho lwm yam kab mob ntawm daim tawv nqaij
- Keratosis Pyilis: Azelaic acid tuaj yeem pab txo cov tawv nqaij, tsa cov tawv nqaij sib txuam nrog keratosis pilaris.
- Lwm cov kab mob tawv nqaij tawv: nws tseem muaj qee yam kev cuam tshuam rau lwm yam mob tawv nqaij cov kab mob xws li eczema thiab psoriasis.
Dab tsi yog cov ntawv thov ntawmAzelaic acid?
1. Kho pob txuv: cov ntsiab lus npaj
- Pob txuv cream thiab gels: azelaic acid feem ntau siv nyob rau hauv kev npaj cov tshuaj txhuam hniav me me kom haum pob txuv. Nws pab txo tus naj npawb ntawm pob txuv thiab tiv thaiv kev tsim cov tshiab.
- Kev kho kev kho: feem ntau siv nyob rau hauv lwm txoj kev kho pob txuv xws li benzoyl peroxide lossis reginoic acid los txhim kho kev ua haujlwm zoo.
2. Kev kho mob Rosacea: anti-inflammatory npaj
- Rosacea cream thiab gels: azelaic acid zoo txo cov liab thiab feem ntau siv nyob rau hauv kev npaj cov ntsiab lus tshwj xeeb ntawm rosacea.
- Kev tswj lub sijhawm ntev: Haum rau kev tswj kom ntev ntawm Rosacea, pab tswj lub xeev ruaj khov.
3. Txhim Kho Cov Pirmentation: Cov Khoom Siv Kom Zoo
- Kev ua rau cov cream thiab lom zem: Azelaic acid pab txo cov xim thiab Melasma los ntawm kev ua haujlwm rau cov kev ua si ntawm Melanin.
- Txawm tias cov tawv nqaij Tone: siv cov txiaj ntsig tsis tu ncua hauv cov tawv nqaij, txo cov xim tsaus nti thiab tsis sib xws thiab tsis sib xws.
4. Antioxidant thiab anti-anti-antioxidant tawv nqaij tu cov khooms
- Anti-laus cream thiab serums: cov tshuaj antioxidant ntawm Azelaic acid ua rau nws cov tawv nqaij tseem ceeb rau cov tawv nqaij thiab qeeb qeeb ntawm cov tawv nqaij.
- Kev tu tawv nqaij txhua hnub: haum rau kev tu tawv nqaij txhua hnub, muab tshuaj tiv thaiv kab mob antioxidant thiab ua kom daim tawv nqaij noj qab haus huv.
5. Kev kho mob ntawm cov post-inflammatory pigmentation (PIH): POSSIONS kho cov khoom lag luam
- Kho cov tshuaj thiab cov hlab ntsha: azelaic acid muaj txiaj ntsig zoo hyperpigmentation thiab feem ntau yog siv hauv kev kho cream thiab cov quav los pab ua kom nrawm dua qhov poob ntawm hyperpigmentation.
- Kev kho cov tawv nqaij: Txhawb kev tsim kho dua tshiab thiab kho cov tawv nqaij hlwb thiab ua kom nrawm fading ntawm pigmentation.
6. Kho lwm yam kab mob ntawm daim tawv nqaij
Keratosis parilis
- Keratin cov khoom cua txias: Azelaic acid tuaj yeem pab txo cov tawv nqaij, tsa cov tawv nqaij uas cuam tshuam nrog keratosis pilaris thiab feem ntau siv nyob rau hauv keratin txias khoom.
- Tawv Smoothing: txhawb cov tawv nqaij smoothness thiab mos, txhim kho tawv nqaij kev ntxhib los mos.
Lwm Cov Kab Mob Ntawm Cov Hlob
- Eczema thiab psoriasis: Azelaic acid kuj muaj qee yam kev mob tawv nqaij rau lwm cov tawv nqaij cov kab mob xws li eczema thiab psoriasis, thiab feem ntau siv hauv kev npaj sib txawv.
7. Ntshai kev saib xyuas: anti-mob thiab cov khoom tiv thaiv kab mob antibacterial
- Cov khoom tu tawv taub: azelaic acid isti-incertatory thiab cov tshuaj tua kabmob puas ua rau siv rau hauv tawv taub hau thiab tuaj yeem kis tawv.
- Cov tawv nqaij tawv nqaij: txhawb nqa tawv taub hau kev noj qab haus huv thiab txo cov dandruff thiab khaus.
Cov lus nug ntsig txog koj tuaj yeem txaus siab rau:
Puasazelaic acidPuas muaj kev phiv?
Azelaic acid tuaj yeem muaj cov kev mob tshwm sim, txawm tias nws yog feem ntau tau zam feem ntau los ntawm cov neeg feem coob. Cov kev mob tshwm sim feem ntau yog me thiab zoo li ploj zuj zus nrog kev siv txuas ntxiv. Nov yog qee qhov tshwm sim tshwm sim thiab kev txiav txim siab:
1. Cov kev mob tshwm sim
Daim tawv nqaij voos
- Cov tsos mob: me quav khaus, liab, khaus, los yog khaus ntawm daim ntawv thov.
- Kev tswj hwm: Cov tsos mob no feem ntau nyob raws li koj cov tawv nqaij hloov kho rau kev kho mob. Yog tias txob txob txob, tej zaum koj yuav xav tau txo cov kev thov lossis sab laj nrog tus kws kho mob.
Diav thiab tev
- Cov tsos mob: Dryness, flaking, lossis tev ntawm daim tawv nqaij.
- Kev tswj hwm: Siv cov tshuaj tiv thaiv maj mam los txo cov tshuab ziab khaub ncaws thiab tswj cov dej ua paug.
2. Feem ntau cov kev mob tshwm sim
Kev xav txawv txav
- Cov tsos mob:: Ua qog khaus heev, pob khaus, lossis khaus.
- Kev tswj hwm: Ua haujlwm siv tam sim ntawd thiab sab laj nrog tus kws kho mob yog tias koj muaj kev fab tshuaj ua xua.
Nce tshav rhiab
- Cov tsos mob: nce rhiab rau hnub ci, ua rau tshav ntuj lossis lub hnub puas tsuaj.
- Kev tswj hwm: Siv cov tshuaj pleev thaiv dav-spectrum txhua hnub thiab tsis txhob muaj hnub ci ci.
3. Tsis muaj kev phiv
Cov tawv nqaij hnyav hnyav
- Cov tsos mob: liab qab loj, yaug ntshav, lossis tev heev.
- Kev tswj hwm: Ua haujlwm siv thiab nrhiav lus qhia txog kev kho mob yog tias koj tau hnov cov kheej hnyav.
4. Kev ceev faj thiab kev txiav txim siab
PATE TEST
- Cov lus pom zoo: Ua ntej siv cov kua qaub Azelaic, ua ib qho chaw kuaj ntawm thaj chaw me me ntawm daim tawv nqaij txhawm rau kuaj xyuas cov kev cuam tshuam tsis zoo.
Cov Lus Taw Qhia GRODRAH
- Cov lus pom zoo: Yog tias koj yog tus tshiab rau Azelaic acid, pib nrog txo qis dua thiab maj mam nce cov zaus ntawm daim ntawv thov kom koj cov tawv nqaij kom haum.
Kev saj laj
- Kev pom zoo: Sab laj tus kws kho mob dermatologist lossis tus kws kho mob ua ntej pib cov tawv nqaij szelaic, tshwj xeeb yog tias koj muaj lwm cov khoom xyaw ua si.
5. Cov neeg tshwj xeeb
Cev xeeb tub thiab pub niam mis
- Kev Nyab Xeeb: Azelaic acid feem ntau yog saib xyuas muaj kev nyab xeeb thaum cev xeeb tub thiab pub mis niam, tab sis nws yog ib qho zoo tshaj plaws los sab laj nrog kev kho mob tshiab.
Rhiab tawv
- Kev Txiav Txim Siab: Cov tib neeg muaj cov tawv nqaij rhiab yuav tsum siv cov kua tawv rhiab nrog kev ceev faj thiab tuaj yeem tau txais txiaj ntsig los ntawm cov qauv tsim rau cov tawv nqaij rhiab.
Ntev npaum li cas nws siv sijhawm kom pom cov txiaj ntsig ntawmazelaic acid?
Lub sijhawm nws yuav siv los pom cov txiaj ntsig los ntawm Azelaic acid tuaj yeem pom ntau dua 2 txog 4 asthiv rau Rosacea, thiab 4 txog 8 lub lis piam rau hyperpigmentation thiab melasma. Ntau cov ntsiab lus tseem ceeb ib txwm tshwm sim tom qab 8 txog 12 lub lis piam ntawm kev siv xwm yeem siv. Yam khoom xws li cov concentration ntawm azelaic acid, zaus ntawm daim ntawv thov, thiab qhov mob tawv nqaij tuaj yeem cuam tshuam qhov ua tau zoo thiab nrawm ntawm cov txiaj ntsig. Kev siv tsis tu ncua thiab tsis tu ncua, nrog rau cov kev coj ua tsis zoo, tuaj yeem pab ua tiav cov txiaj ntsig zoo tshaj plaws.
Yam cuam tshuam tshwm sim
Concentration ntawm azelaic acid
Cov ntau dua: Cov khoom lag luam nrog cov acid ntau dua ntawm Azelaic acid (piv txwv li, 15% rau 20%) tej zaum yuav ua rau pom tau sai thiab ntxiv tau.
Cov qis dua: cov khoom lag luam nrog cov qis dua yuav siv sijhawm ntev dua los ua kom pom qhov tshwm sim pom.
Zaus ntawm daim ntawv thov
Kev Siv Zoo Li: Thov cov kua qaub azelaic raws li qhia, feem ntau yog ib zaug lossis ob zaug ib hnub, tuaj yeem txhim kho cov txiaj ntsig zoo thiab ua kom ceev.
Kev siv tsis sib haum: Daim ntawv thov tsis xwm yeem yuav ncua cov kev pom thiab txo qis kev ua tau zoo tag nrho.
Tus Cwj Pwm Ntawm Ib Leeg Cov tawv nqaij
Cov Ntaus tawv nqaij Ntaus: Ib qho khoom tawv nqaij thiab mob tawv thiab yuav cuam tshuam kom pom sai npaum li cas. Piv txwv li, cov tib neeg uas muaj cov tawv nqaij tawv tawv yuav pom tau sai dua rau cov uas muaj lub suab dub dub.
Kev mob hnyav: tus mob hnyav ntawm daim tawv nqaij raug kho kuj tuaj yeem cuam tshuam rau lub sijhawm nws yuav siv sijhawm kom pom cov txiaj ntsig. Cov xwm txheej me me tuaj yeem teb nrawm dua li muaj mob hnyav dua.
Thaum twg siv zelaic acid, thaum sawv ntxov lossis hmo ntuj?
Azelaic acid tuaj yeem siv ob qho tib si thaum sawv ntxov thiab tsaus ntuj, nyob ntawm koj cov kev xav tau ntawm cov tawv nqaij tawv thiab cov kev xav tau tshwj xeeb. Yog tias siv thaum sawv ntxov, ib txwm ua raws nrog tshuaj pleev thaiv hnub tiv thaiv kom tiv thaiv koj cov tawv nqaij los ntawm UV puas. Siv nws thaum hmo ntuj tuaj yeem txhim kho cov tawv nqaij kho thiab txo qis kev cuam tshuam nrog lwm cov khoom xyaw nquag. Rau cov txiaj ntsig siab tshaj plaws, qee tus neeg xaiv siv cov kua pa zelaic thaum sawv ntxov thiab hmo ntuj, tab sis nws yog qhov tseem ceeb los soj ntsuam koj cov tawv nqaij teb thiab kho raws. Nco ntsoov siv Azelaic acid tom qab ntxuav thiab ua ntej moisturizing, thiab xav li cas nws haum rau koj cov txiaj ntsig nyuaj nyuaj ua kom tiav cov txiaj ntsig zoo tshaj plaws
Dab tsi tsis sib xyaw nrogazelaic acid?
Azelaic acid yog ib qho muaj peev xwm thiab feem ntau ua kom muaj kev zam rau kev ua kom zoo nkauj, tab sis nws yog qhov tseem ceeb uas nws cuam tshuam nrog lwm cov khoom xyaw ua haujlwm hauv koj cov tawv nqaij. Sib tov qee cov khoom xyaw tuaj yeem ua rau voos, txo cov txiaj ntsig, lossis lwm yam tsis xav tau. Nov yog qee cov lus qhia ntawm yam uas tsis sib tov nrog Azelaic acid:
1.. Muaj zog exfoliants
Alpha Hydroxy acids (Ahas)
- Cov piv txwv: accolic acid, lactic acid, mandelic acid.
- Vim li cas: sib txuas zelaic acid nrog muaj zog Aha tuaj yeem ua rau muaj kev pheej hmoo ntawm, liab, thiab tev. Ob qho tib si yog exfoliants, thiab siv lawv ua ke tuaj yeem ua dhau ntawm daim tawv nqaij.
Beta hydroxy acids (Bhas)
- Cov piv txwv: salicylic acid.
- Vim li cas: Zoo ib yam li Ahas, Bhas kuj muaj exfoliants. Siv lawv ua ke nrog Azelaic acid tuaj yeem ua rau dhau-exfoliation thiab cov tawv nqaij rhiab.
2. Retinoids
- Cov piv txwv: Retinol, retinaldehyde, tretinoin, adapalene.
- Vim li cas: retinoids tau muaj zog cov khoom xyaw uas tuaj yeem ua rau qhuav, tev, thiab voos, tshwj xeeb yog thaum ua ntej qhia. Sib txuas ua ke nrog hzelaic acid tuaj yeem exacerbate cov kev mob tshwm sim no.
3. Benzoyl Peroxide
Qho tseem ceeb
- Iritation: Benzoyl peroxide yog cov pob txuv muaj zog uas tuaj yeem ua rau qhuav thiab voos. Siv nws nrog cov acid azelaic tuaj yeem ua rau muaj kev pheej hmoo ntawm daim tawv nqaij khaus.
- Txo kev ua tau zoo: benzoyl peroxide kuj tseem tuaj yeem oxidize lwm cov khoom xyaw nquag, muaj peev xwm txo lawv cov txiaj ntsig.
4. Vitamin C (ascorbic acid)
Qho tseem ceeb
- P theem: Vitamin C (ascorbic acid) yuav tsum muaj pH tsis muaj txiaj ntsig zoo, thaum angelaic ua haujlwm zoo dua ntawm Ph. Siv lawv ua ke tuaj yeem ua rau muaj kev ua tau zoo ntawm ob qho khoom xyaw.
- IRITITT: sib txuas ntawm ob cov khoom xyaw muaj zog no tuaj yeem ua rau muaj kev pheej hmoo khaus, tshwj xeeb tshaj yog cov tawv nqaij rhiab.
5. Niacinamide
Qho tseem ceeb
- Muaj peev xwm sib txuam: Thaum Niacinamide feem ntau yog siv tau zoo nrog ntau tus neeg tuaj yeem ua rau muaj kev txob txob thaum sib txuas ua ke thaum ua ke nrog cov pa roj somit. Qhov no tsis yog txoj cai universal, tab sis nws yog ib yam dab tsi yuav tsum tau paub txog.
6. Lwm lub zog ua haujlwm
Piv txwv
- Hydroquinone, koJic acid, thiab lwm cov tawv nqaij tawv nqaij.
- Vim li cas: ua ke ntau lub hwj chim ua kom muaj kev pheej hmoo ua tau rau kev pheej hmoo ntawm cov kev pheej hmoo thiab tej zaum yuav tsis tsim nyog txhim kho kev ua tau zoo.
Yuav ua li cas tso paAzelaic acidKev nyab xeeb:
Hloov kojse
- Lub tswv yim: Yog tias koj xav siv Azelaic acid nyob nrog lwm yam muaj zog, xav txog kev siv. Piv txwv li, siv cov kua qaub azelaic thaum sawv ntxov thiab retinoids lossis Ahas / Bhas thaum tsaus ntuj.
PATE TEST
- Cov lus pom zoo: Yuav tsum ua ib daim duab ntsuas thaum qhia cov khoom siv nquag tshiab rau koj txoj kev ua kom pom zoo.
Pib maj mam
- Lub tswv yim: Qhia Azelaic Acid Abrasual maj, pib nrog qis dua kev xav thiab nce zaus raws li koj cov tawv nqaij ua kom ntev.
Sab laj tus kws kho mob dermatologist
- Cov lus pom zoo: Yog tias koj tsis paub meej txog yuav ua li cas rau hauv koj txoj kev ua si, sab laj tus kws kho mob dermatologist rau cov lus qhia tus kheej.
Lub Sijhawm Post: Sep-21-2024
