Newgreen Hoobkas Supply Topotecan Hydrochloride Zoo 99% Topotecan Hydrochloride Hmoov
Product Description
Topotecan Hydrochloride yog ib qho tshuaj khomob uas siv los kho qee yam mob qog noj ntshav. Nws yog daim ntawv hydrochloride ntawm topotecan, topoisomerase inhibitor uas ua haujlwm feem ntau los ntawm inhibiting cov haujlwm ntawm DNA topoisomerase I.
Nco tseg:
Thaum siv Topotecan, cov neeg mob yuav tsum nyob rau hauv kev taw qhia ntawm tus kws kho mob, tshwj xeeb tshaj yog rau cov neeg mob uas muaj lub siab thiab lub raum tsis ua haujlwm lossis lwm yam teeb meem kev noj qab haus huv. Kev kuaj ntshav tsis tu ncua yuav tsum tau ua thaum kho los saib xyuas cov kev mob tshwm sim.
Hauv kev xaus, Topotecan Hydrochloride yog ib qho tseem ceeb tshuaj tiv thaiv kab mob, feem ntau yog siv los kho mob qog noj ntshav ntawm zes qe menyuam thiab qog nqaij hlav qog nqaij hlav me me, thiab muaj txiaj ntsig tseem ceeb hauv kev kho mob.
COA
Cov khoom | Specifications | Cov txiaj ntsig |
Qhov tshwm sim | Tawm-dawb los yog hmoov dawb | Dawb hmoov |
HPLC Identification | Raws li kev siv cov khoom tseem ceeb ncov lub sijhawm khaws cia | Ua raws |
Kev sib hloov tshwj xeeb | +20.0.-22.0.0 Nws. | +21. |
Cov hlau hnyav | ≤ 10ppm | <10ppm |
PH | 7.5-8.5 Nws | 8.0 ib |
Poob rau ziab | ≤ 1.0% | 0.25% |
Coj | ≤ 3ppm | Ua raws |
Arsenic | ≤1ppm | Ua raws |
Cadmium | ≤1ppm | Ua raws |
Mercury | ≤0. 1ppm ua | Ua raws |
Melting point | 250.0 Nws℃~ 265.0℃ | 254.7–255.8℃ |
Residue ntawm ignition | ≤0. 1% | 0.03% |
Hydrazine | ≤ 2ppm | Ua raws |
Qhov ntom ntom | / | 0.21g / ml |
Tapped ntom | / | 0.45g / ml |
Assay(Topotecan Hydrochloride) | 99.0% ~ 101.0% | 99.65% |
Tag nrho aerobes suav | ≤1000CFU / g | <2CFU/g |
Pwm & Poov xab | ≤100CFU / g | <2CFU/g |
E.coli | Tsis zoo | Tsis zoo |
Salmonella | Tsis zoo | Tsis zoo |
Cia | Khaws rau hauv qhov chaw txias & qhuav, kom deb ntawm lub teeb muaj zog. | |
Xaus | Tsim nyog |
Muaj nuj nqi
Topotecan Hydrochloride yog ib qho tshuaj khomob uas siv los kho qee yam mob qog noj ntshav. Nws yog ib qho topoisomerase inhibitor nrog cov txheej txheem tshwj xeeb ntawm kev ua thiab kev ua haujlwm:
Muaj nuj nqi:
1.Topoisomerase inhibition: Topotecan cuam tshuam nrog DNA replication thiab transcription los ntawm inhibiting cov kev ua ntawm topoisomerase I. Qhov no inhibition ua rau lub breakage ntawm DNA chains, yog li tiv thaiv lub proliferation ntawm cancer hlwb.
2.Kev tiv thaiv kab mob: Topotecan feem ntau yog siv los kho mob qog noj ntshav ntawm zes qe menyuam, qog nqaij hlav qog nqaij hlav me me thiab qee hom qog ntshav qog ntshav. Nws tuaj yeem siv los ua thawj kab kev kho mob lossis kev kho mob thib ob tom qab lwm cov kev kho mob ua tsis tiav.
3.Cell voj voog tshwj xeeb: Topotecan cov nyhuv ntawm lub voj voog ntawm tes feem ntau tshwm sim nyob rau theem S thiab G2, uas ua rau nws muaj zog tua cov qog nqaij hlav qog nqaij hlav hauv ib theem cell proliferation.
4.Combination kho mob: Topotecan tuaj yeem siv ua ke nrog lwm cov tshuaj khomob los txhim kho cov nyhuv tiv thaiv qog thiab txhim kho tus neeg mob cov lus teb.
5. Kho cov tsos mob: Qee zaum, kev siv Topotecan tuaj yeem pab txo cov tsos mob ntsig txog mob qog noj ntshav thiab txhim kho tus neeg mob lub neej zoo.
Nco tseg:
Topotecan tuaj yeem ua rau qee qhov kev mob tshwm sim, suav nrog tab sis tsis txwv rau xeev siab, ntuav, qaug zog, leukopenia, thiab lwm yam. Thaum siv cov tshuaj no, cov neeg mob yuav tsum tau saib xyuas thiab tswj xyuas raws li tus kws kho mob cov lus qhia.
Hauv kev xaus, Topotecan Hydrochloride yog ib qho tshuaj tiv thaiv kab mob zoo uas ua rau nws cov tshuaj tiv thaiv kab mob feem ntau los ntawm inhibition ntawm DNA topoisomerase I.
Daim ntawv thov
Topotecan Hydrochloride yog ib qho tshuaj khomob uas siv los kho qee yam mob qog noj ntshav. Cov hauv qab no yog nws cov kev siv tseem ceeb:
1.Ovarian cancer: Topotecan feem ntau yog siv los kho mob qog noj ntshav ntawm zes qe menyuam, tshwj xeeb tshaj yog nyob rau hauv cov neeg mob tom qab lwm yam kev kho mob (xws li platinum-based chemotherapy) ua tsis tiav. Nws tuaj yeem siv los ua ib tus neeg sawv cev lossis ua ke nrog lwm yam tshuaj.
2.Small cell ntsws cancer: Cov tshuaj no kuj tseem siv tau rau kev kho mob qog noj ntshav me me, feem ntau yog kev kho mob thib ob, tshwj xeeb tshaj yog thaum tus kab mob rov qab los tom qab pib siv tshuaj khomob.
3.Lwm Cov Mob Cancer: Txawm hais tias Topotecan feem ntau yog siv rau kev mob qog noj ntshav ntawm zes qe menyuam thiab mob qog noj ntshav me me, nws tseem tau kawm hauv qee qhov kev sim tshuaj rau lwm hom qog noj ntshav, xws li mob qog noj ntshav, mob qog noj ntshav, thiab qee hom qog ntshav qog ntshav.
4. Kev sim tshuaj: Topotecan tseem raug soj ntsuam hauv kev sim tshuaj rau ntau yam qog noj ntshav los kawm txog nws cov txiaj ntsig thiab kev nyab xeeb hauv kev kho mob sib txawv.
5.Kev kho mob ua ke: Qee zaum, Topotecan tuaj yeem siv ua ke nrog lwm cov tshuaj khomob lossis tshuaj kho mob txhawm rau txhim kho cov nyhuv kho.
Nco tseg:
Thaum siv Topotecan, cov neeg mob yuav tsum nyob rau hauv kev taw qhia ntawm tus kws kho mob, tshwj xeeb tshaj yog rau cov neeg mob uas muaj lub siab thiab lub raum tsis ua haujlwm lossis lwm yam teeb meem kev noj qab haus huv. Kev kuaj ntshav tsis tu ncua yuav tsum tau ua thaum kho los saib xyuas cov kev mob tshwm sim.
Hauv kev xaus, Topotecan Hydrochloride muaj cov txiaj ntsig tseem ceeb hauv kev kho mob qog noj ntshav, tshwj xeeb tshaj yog nyob rau hauv kev tswj cov qog nqaij hlav zes qe menyuam thiab qog nqaij hlav me me.