Lycopene: Hoʻomaikaʻi i ka Motility Sperm a pale i ka hoʻonui ʻana o ka maʻi maʻi prostate

• He aha nā pōmaikaʻi oLycopeneNo ka prostate kane ?

1. Ka maʻi maʻi prostate

He maʻi maʻamau ka maʻi prostatic hyperplasia i nā kāne, a i nā makahiki i hala iho nei, ua emi loa ka nui o ka maʻi. ʻO nā hōʻailona o ka ʻāpana mimi haʻahaʻa (ka wikiwiki mimi / mimi pinepine / mimi piha ʻole) ʻo ia nā hōʻike lapaʻau nui, e hoʻopilikia nui i ka maikaʻi o ke ola o nā maʻi.

Lycopenehiki ke pale i ka hoʻonui ʻana o nā cell epithelial prostate, hoʻoikaika i ka apoptosis i loko o ka ʻiʻo prostate, hoʻoulu i ke kamaʻilio intercellular gap junction e pale i ka māhele cell, a hoʻemi pono i nā pae o nā mea inflammatory e like me interleukin IL-1, IL-6, IL-8 a me ka necrosis tumor. kumu (TNF-α) e hana i nā hopena anti-inflammatory.

Ua ʻike ʻia nā hoʻokolohua lapaʻau e hiki i ka lycopene ke hoʻomaikaʻi i ka hyperplasia prostate a me ka hoʻoheheʻe ʻana o ka ʻiʻo maʻemaʻe o ka ʻiʻo i loko o ka poʻe momona a hoʻomaha i nā hōʻailona o ka ʻāpana mimi kāne haʻahaʻa. Loaʻa ka Lycopene i ka hopena maikaʻi a me ka hoʻomaikaʻi ʻana i nā hōʻailona o ka maʻi mimi haʻahaʻa i hoʻokumu ʻia e ka prostate hypertrophy a me ka hyperplasia, e pili ana i ka ikaika antioxidant a me nā hopena anti-inflammatory o lycopene.

2. Ka ma'i ma'i prostate

Nui nā palapala lapaʻau e kākoʻo ana i kēlālycopenei ka ʻai ʻana i kēlā me kēia lā he kuleana koʻikoʻi ia i ka pale ʻana i ka maʻi prostate, a ʻo ka ʻai ʻana o ka lycopene ua pili maikaʻi ʻia me ka pilikia o ka maʻi prostate. Ua manaʻo ʻia e pili ana kāna mīkini i ka hoʻopili ʻana i ka hōʻike ʻana o nā genes a me nā protein e pili ana i ka maʻi maʻi, kaohi ʻana i ka hoʻonui ʻana o ka maʻi maʻi a me ka adhesion, a me ka hoʻonui ʻana i ke kamaʻilio intercellular.

ʻO ka hoʻokolohua i ka hopena o ka lycopene i ke ola ola o nā pūnaewele maʻi prostate kanaka: Ma nā hoʻokolohua lapaʻau lapaʻau, ua hoʻohana ʻia ka lycopene e mālama i nā laina cell cancer prostate kanaka DU-145 a me LNCaP.

Ua hōʻike nā hopenalycopeneUa loaʻa i ka hopena inhibitory koʻikoʻi i ka hoʻonui ʻana o nā pūnaewele DU-145, a ʻike ʻia ka hopena inhibitory ma 8μmol / L. Hoʻopili maikaʻi ʻia ka hopena inhibitory o ka lycopene ma luna o ka hopena, a hiki i ka nui o ka inhibition rate hiki ke hiki i 78%. I ka manawa like, hiki iā ia ke pale nui i ka hoʻonui ʻana o LNCaP, a aia kahi pilina pili hopena-hopena. ʻO ka nui o ka inhibition rate ma ka pae o 40μmol / L hiki ke hiki i 90%.

Hōʻike nā hopena i hiki i ka lycopene ke kāohi i ka hoʻonui ʻana o nā sela prostate a hoʻemi i ka hopena o nā maʻi maʻi prostate e lilo i ka maʻi kanesa.