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Coenzyme Q10 – He mea hoʻololi ikehu no ka Cellular Mitochondria

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He ahaCoenzyme Q10?

ʻO Coenzyme Q10 (Coenzyme Q10, CoQ10), ʻike ʻia ʻo Ubiquinone (UQ) a me Coenzyme Q (CoQ), he coenzyme i loaʻa i nā mea ola eukaryotic a pau e hana ana i ka hanu aerobic. ʻO ia ka benzoquinone fat-soluble compound me kahi ʻano like me ka vitamina K. Q ka hui quinone, a ʻo 10 ka helu o ka isoprene i hoʻopili ʻia i kona huelo. Hoʻokumu nuiʻia i loko o ka membrane o loko o ka mitochondria, a hiki ke loaʻa kahi hapa liʻiliʻi ma o ka meaʻai, e like me ka pipi, nā hua manu, nā iʻaʻaila, nā nati, nāʻalani, broccoli a me nā huaʻai a me nā huaʻai.

Hoʻolaha nui ʻia ka Coenzyme Q10 i loko o ke kino o ke kanaka a aia i loko o nā ʻāpana like ʻole, nā ʻiʻo, nā ʻāpana subcellular a me ka plasma, akā ʻokoʻa loa kona ʻike. ʻOi aku ka kiʻekiʻe o ka ʻike nui ma nā ʻiʻo a me nā ʻāpana e like me ke ake, naʻau, nā puʻupaʻa a me ka pancreas. ʻO ka hana nui, ʻo ia ka hoʻoulu ʻana i nā cell kanaka e hana i ka ikehu. Hoʻokomo nui ʻia ʻo Coenzyme Q10 i ka mitochondrial oxidative phosphorylation a me ke kaʻina hana ATP, hoʻoponopono i ke kaiapuni redox cell, lawe i nā electrons i hoʻemi ʻia i loko o ka vesicle a i waho o ke kelepona i ka wā o ke kaʻina hana o ka membrane electron, a komo i ka hoʻokumu ʻana o ka gradient proton o ka membrane i loko a me ka membrane plasma. Hiki iā ia ke hoʻolalelale i ka hana hou ʻana o ka cell a hoʻoulu i ka hana o ka cell, a laila e hoʻoikaika nui i ka hiki o nā cell ke komo i nā meaʻai. ʻO ka hoʻohui ʻana i nā mea coenzyme Q10 i nā huahana mālama ʻili hiki ke kōkua maikaʻi i nā ʻili o ka ʻili e komo ikaika i nā meaʻai ʻē aʻe i loko o nā huahana mālama ʻili, a loaʻa nā hopena mālama ola e like me ka hoʻolalelale ʻana i ka metabolism a me ka lohi ʻana i ka ʻelemakule.

Ma ke ʻano he huahana olakino, loaʻa i ka coenzyme Q10 nā hana o ka pale ʻana i ka puʻuwai, hoʻonui i ka ikehu, a hoʻomaikaʻi i ka pale ʻana. He kūpono ia no nā mea pāʻani, nā limahana noʻonoʻo kiʻekiʻe, a me ka hoʻopaʻa ʻana a me ka hoʻihoʻi ʻana o nā maʻi me ka maʻi maʻi puʻuwai, diabetes, etc.

Ke Kino A me Kemika oCoenzyme Q10

ʻO ke ʻano o Coenzyme Q10:Melemele a ʻalani-melemele ka pauka crystalline; ʻala ʻole a ʻono ʻole; hiki ke popopo e ka malamalama.

kala:ʻalani māmā i ʻalani ʻeleʻele

Lae hehee:49-51 ℃

Lae paila:715.32 ℃

ʻO ka mānoanoa:0.9145 g/cm3

Hōʻike hōʻikeʻike:1.4760

Nā kūlana mālama:Hiki ke mālama ʻia ma ka lumi wela no kahi manawa pōkole, ʻoi aku ka maikaʻi ma -20 ℃ no ka mālama lōʻihi.

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia i loko o ka chloroform.

ʻIkepili:kiʻi kiʻi

Paʻa:Paʻa, akā ʻoluʻolu i ka māmā a i ʻole ka wela, ʻaʻole kūpono me nā oxidants ikaika.

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Mahele OCoenzyme Q10I Ke Kino Kanaka

Loaʻa ka Coenzyme Q10 i loko o nā membrane cell, ʻoi aku hoʻi i nā membrane mitochondrial, a ua māhele nui ʻia i loko o ka puʻuwai, ka māmā, ka ate, nā puʻupaʻa, ka spleen, pancreatic a me nā kelepa adrenal. ʻO ka nui o ke kino o Coenzyme Q10 he 500 ~ 1500mg wale nō, akā he mea nui ia. He kiʻekiʻe ka Coenzyme Q10 i loko o ka puʻuwai, puʻupaʻa, ate a me nā ʻiʻo. I ka manawa like, aia ka 95% o Coenzyme Q10 i loko o ke kino o ke kanaka ma ke ʻano o ka ubiquinol (hoʻemi ʻia ʻo Ubiquinol), akā ua kāpae ʻia ka lolo a me nā māmā. Manaʻo ʻia ʻo ia paha ma muli o ke koʻikoʻi oxidative kiʻekiʻe o kēia mau ʻiʻo ʻelua, ka mea e hoʻokahe i ka ubiquinol i ubiquinone oxidized (oxidized Ubiquinone).

Me ka emi ʻana o ka makahiki, e emi mālie ka ʻike o Coenzyme Q10 i ke kino o ke kanaka. ʻO ka lawe ʻana i 20 mau makahiki ma ke ʻano he laina maʻamau, i ka makahiki o 80, ʻo ka attenuation kūlohelohe o Coenzyme Q10 ma nā ʻāpana like ʻole o ke kino kanaka ʻo ia: ate: 83.0%; ʻākena: 65.3%; ʻāmāmā: 51.7%; naʻau: 42.9%. No laila, ua ʻae ʻia ʻo ka puʻuwai ka ʻōkana e pono ai i ka coenzyme Q10 supplementation, a i ʻole ka nui o nā pilikia o ka naʻau o ka poʻe ʻelemakule ma muli o ka nele o ka coenzyme Q10.

He aha nā pōmaikaʻi oCoenzyme Q10?

ʻO kekahi o nā pono kūpono o CoQ10 ka:

1. Hoʻomaikaʻi ʻia ke olakino naʻau:Ua hōʻike ʻia ʻo CoQ10 e kākoʻo i ke olakino puʻuwai ma ke kōkua ʻana i ka hoʻomaikaʻi ʻana i ka hana ikehu i loko o ka ʻiʻo puʻuwai, a me ka hana ʻana ma ke ʻano he antioxidant e pale aku ai i ke kaumaha oxidative.

2. Hoʻonui i ka ikehu hana:Hoʻokomo ʻia ʻo CoQ10 i ka hana ʻana o adenosine triphosphate (ATP), ʻo ia ka kumu kumu ikehu no nā cell. Hiki ke kōkua ka hoʻohui ʻana me CoQ10 i ka hoʻonui ʻana i nā pae ikehu, ʻoi loa i nā poʻe me nā pae haʻahaʻa CoQ10.

3. Nā waiwai antioxidant:Kōkua ʻo CoQ10 i ka pale ʻana i nā radical manuahi a hōʻemi i ka pōʻino oxidative i ke kino, hiki ke kōkua i ka pale ʻana i nā maʻi maʻi like ʻole a kākoʻo i ke olakino holoʻokoʻa.

4. Nā hopena kū'ē i ka wā kahiko:Ke hōʻike nei kekahi mau noiʻi e loaʻa paha i ka CoQ10 nā hopena anti-aging ma muli o kona hiki ke pale aku i nā cell mai ka pōʻino oxidative a kākoʻo i ka hana ikehu cellular.

5. Kākoʻo no nā mea hoʻohana statin:ʻO nā lāʻau statin, ka mea maʻamau i kuhikuhi ʻia e hoʻohaʻahaʻa i ka cholesterol, hiki ke hoʻopau i nā pae CoQ10 i ke kino. Hiki ke kōkua ka hoʻohui ʻana me CoQ10 i ka hoʻēmi ʻana i nā hopena ʻaoʻao o ka hoʻohana ʻana i ka statin, e like me ka ʻeha a me ka nāwaliwali.

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He aha nā noi oCoenzyme Q10?

He mau noi ko Coenzyme Q10 (CoQ10) ma muli o kona mau pono olakino. Aia kekahi o nā noi nui o CoQ10:

1. Ola kino naʻau:Hoʻohana pinepine ʻia ʻo CoQ10 no ke kākoʻo ʻana i ke olakino o ka naʻau, ʻoi loa i nā poʻe me ka puʻuwai puʻuwai, ke koko kiʻekiʻe, a i ʻole nā ​​​​maʻi cardiovascular ʻē aʻe. Hiki ke kōkua i ka hoʻonui ʻana i ka ikehu i loko o ka ʻiʻo puʻuwai a hana ma ke ʻano he antioxidant e pale aku ai i ke kaumaha oxidative.

2. Nā maʻi mitochondrial:Hoʻohana ʻia ʻo CoQ10 ma ke ʻano he mea hoʻohui no nā poʻe me nā maʻi mitochondrial, no ka mea he hana koʻikoʻi ia i ka hana ʻana o ka ikehu i loko o ka mitochondria.

3. ʻO ka myopathy i hoʻokomo ʻia e statin:Manaʻo ʻia ka hoʻohui CoQ10 i kekahi manawa no ka poʻe e lawe ana i nā lāʻau statin e hoʻohaʻahaʻa i ka cholesterol, ʻoiai hiki i nā statins ke hoʻopau i nā pae CoQ10 i ke kino. ʻO ka hoʻohui ʻana me CoQ10 hiki ke kōkua i ka hoʻēmi ʻana i ka ʻeha a me ka nāwaliwali e pili ana i ka hoʻohana ʻana i ka statin.

4. Anti-kahiko a me ke ola kino:Hoʻohana ʻia ʻo CoQ10 i kekahi mau huahana mālama ʻili ma muli o kāna mau waiwai antioxidant, hiki ke kōkua i ka pale ʻana i ka ʻili mai ka pōʻino oxidative a kākoʻo i ke olakino ʻili holoʻokoʻa.

5. Ka pale ʻana i ka migraine:Ke hōʻike nei kekahi mau noiʻi e hiki i ka CoQ10 supplementation ke kōkua i ka hōʻemi ʻana i ke alapine a me ka paʻakikī o ka migraines, ʻoiai ʻoi aku ka nui o nā noiʻi e hōʻoia i kona pono no kēia kumu.

6. Hoʻoikaika kino:Hiki ke kōkua ʻo CoQ10 i ka hoʻomaikaʻi ʻana i ka hana hoʻoikaika kino a me ka hoʻihoʻi ʻana ma ke kākoʻo ʻana i ka hana ikehu a me ka hōʻemi ʻana i ke kaumaha oxidative i loko o nā ʻiʻo.

Coenzyme q10 maʻiʻo i loko o nā meaʻai maʻamau

Coenzyme Q10 maʻiʻo no ke kilo o ka meaʻai (mg)

Meaʻai

ʻO ka maʻiʻo CoQ10

Meaʻai

ʻO ka maʻiʻo CoQ10

Sardines

33.6

Kāna

6.9

Saury

26.8

Laiki palaunu

5.4

Puʻuwai puaʻa

25.6

ʻōpae

5.1

ʻĀpaʻa puaʻa

25.1

ʻO nā lau ʻōmaʻomaʻo

3.2

Iʻa ʻeleʻele

25.1

Hoʻopaʻapaʻa

2.7

ʻO ka malo puaʻa

24.7

Kāloti

2.6

Salmon

22.5

Letus

2.5

Mackerel

21.8

ʻOtomato

2.5

Pipi

21.2

hua kiwi

2.4

puaʻa

16.1

Kelelei

2.3

Peanuts

11.3

ʻuala

2.3

Brokoli

10.8

ʻAlani

2.3

cherries

10.7

Eggplant

2.3

Barley

10.6

Piʻi

2.0

Soybeans

7.3

Aʻa lotus

1.3

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Nā nīnau pili hiki iā ʻoe ke hoihoi iā:

He aha nā hopena ʻaoʻao oCoenzyme Q10?

Manaʻo ʻia ʻo Coenzyme Q10 (CoQ10) he palekana no ka hapa nui o ka poʻe i ka wā i lawe ʻia i nā kau kūpono. Eia naʻe, hiki i kekahi poʻe ke loaʻa i nā hopena ʻaoʻao haʻahaʻa. Hiki i kēia mau mea ke komo:

1. Nā pilikia o ka ʻai ʻana:Hiki i kekahi poʻe ke ʻike i nā hōʻailona maʻi ʻōpū e like me ka nausea, ka ʻōpū, a i ʻole ka ʻōpū i ka wā e lawe ai i nā mea hoʻohui CoQ10.

2. Insomnia:I kekahi mau hihia, pili ka CoQ10 supplementation me ka pilikia o ka hiamoe a i ʻole ka insomnia, ʻoiai ke lawe ʻia i ke ahiahi.

3. Nā hopena maʻi:ʻOiai kakaʻikahi, hiki i kekahi poʻe ke maʻi i ka CoQ10 a loaʻa paha i nā hōʻailona e like me ka ʻūhū, ka ʻāʻī, a i ʻole ka pilikia o ka hanu ʻana.

4. Nā pilina me nā lāʻau lapaʻau:Hiki i ka CoQ10 ke launa pū me kekahi mau lāʻau lapaʻau, e like me nā mea hoʻokahe koko a me nā lāʻau no ke koko kiʻekiʻe. He mea nui e kamaʻilio me ke kauka lapaʻau ma mua o ka lawe ʻana i ka CoQ10 inā ʻoe i kekahi lāʻau lapaʻau.

He mea nui e hoʻomaopopo i ka ʻae maikaʻi ʻana o ka hapa nui o ka poʻe iā CoQ10, a ʻaʻole loaʻa nā hopena koʻikoʻi. Eia nō naʻe, e like me nā mea hoʻohui, pono e kūkākūkā me kahi mea mālama ola ma mua o ka hoʻomaka ʻana i ka hoʻohui CoQ10, ʻoi aku ka nui inā loaʻa iā ʻoe nā kūlana olakino a i ʻole e lawe ana i nā lāʻau lapaʻau.

Pono ʻoe e lawe i ka CoQ10 i kēlā me kēia lā?

Pono ka hoʻoholo e lawe i ka Coenzyme Q10 (CoQ10) i kēlā me kēia lā ma muli o nā pono olakino pilikino a me ka ʻōlelo aʻoaʻo a kekahi limahana mālama ola. Hoʻopuka maoli ʻia ʻo CoQ10 i ke kino a loaʻa pū kekahi ma o kekahi mau meaʻai. Eia nō naʻe, i ka wā ʻelemakule a i ʻole nā ​​hihia o kekahi mau kūlana olakino, hiki ke emi mai ka hana kūlohelohe o ke kino o CoQ10.

No nā poʻe e noʻonoʻo ana i ka hoʻohui CoQ10, he mea nui e kūkākūkā me kahi mea mālama olakino e hoʻoholo ai i ke ʻano kūpono a me ka pinepine e pili ana i ke kūlana olakino o kēlā me kēia kanaka, nā hemahema, a me nā kūlana olakino. I kekahi mau hihia, hiki i kekahi kauka mālama ola ke ʻōlelo aku i ka lawe ʻana i ka CoQ10 i kēlā me kēia lā, ʻoiai ma nā kūlana ʻē aʻe, ʻoi aku ka kūpono o kahi papa kuhikuhi dosing ʻē aʻe.

ʻO wai ka mea hiki ʻole ke lawe i ka CoQ10?

Pono kekahi poʻe e makaʻala a hōʻole paha i ka lawe ʻana i ka Coenzyme Q10 (CoQ10) me ka ʻole o ke kamaʻilio ʻana i kahi ʻoihana mālama ola. Hiki i kēia mau mea ke komo:

1. Nā wāhine hāpai a hānai paha:ʻOiai ʻo CoQ10 ka mea maʻamau i manaʻo ʻia he palekana, aia ka palena o ka noiʻi e pili ana i kona palekana i ka wā hāpai a me ka hānai ʻana. No laila, ʻoi aku ka maikaʻi o nā wahine hāpai a hānai paha e kūkākūkā me kahi mea mālama ola ma mua o ka hoʻohana ʻana iā CoQ10.

2. Ka poe e lawe ana i na laau hoemi koko:Hiki ke launa pū ʻo CoQ10 me nā lāʻau anticoagulant e like me warfarin (Coumadin) a i ʻole nā ​​lāʻau antiplatelet e like me ka aspirin. He mea nui i ka poʻe ma kēia mau lāʻau e ʻimi i ka ʻōlelo aʻo lapaʻau ma mua o ka hoʻomaka ʻana i ka hoʻohui CoQ10.

3. ʻO nā kānaka me nā maʻi olakino e kū nei:ʻO ka poʻe me kekahi mau maʻi olakino, e like me ka maʻi ate, ka maʻi kīkī, a i ʻole ka maʻi diabetes, pono e kūkākūkā me kahi mea mālama ola ma mua o ka lawe ʻana i ka CoQ10, no ka mea hiki ke launa pū me nā lāʻau i hoʻohana ʻia e mālama i kēia mau kūlana.

4. ʻO ka poʻe me nā maʻi ʻaleʻale i ʻike ʻia:ʻO ka poʻe i ʻike i ka maʻi allergies i CoQ10 a i ʻole nā ​​​​huihui e pili ana e pale i ka hoʻohana ʻana.

He aha nā hōʻailona o ka ponoCoQ10?

ʻAʻole maʻalahi nā hōʻailona o ka makemake ʻana i ka Coenzyme Q10 (CoQ10), no ka mea hiki ke maʻalahi a paʻa paha me nā hōʻailona o nā kūlana olakino. Eia nō naʻe, ʻo kekahi mau hōʻailona hiki ke hōʻike i kahi hemahema o CoQ10 e komo pū ana:

1. Ka luhi a me ka ikehu haahaa:He kuleana koʻikoʻi ka CoQ10 i ka hana ʻana i ka ikehu cellular. No laila, ʻo ka luhi mau a me ka haʻahaʻa haʻahaʻa o ka ikehu hiki ke lilo i hōʻailona o ka hemahema CoQ10.

2. Nawaliwali a me ka ʻeha o ka ʻiʻo:Hiki i ka hemahema o CoQ10 ke kōkua i ka nāwaliwali o ka ʻiʻo, ka ʻeha, a me ka ʻeha, no ka mea, pili ia i ka hana ikehu i loko o nā ʻiʻo.

3. Ke koko kiʻekiʻe:Ke hōʻike nei kekahi mau noiʻi e pili ana nā haʻahaʻa haʻahaʻa o CoQ10 me ke koko kiʻekiʻe, a hiki i ka supplementation ke kōkua i ke olakino cardiovascular.

4. ʻO ka maʻi gum:Hoʻopili ʻia ʻo CoQ10 i ka mālama ʻana i ka ʻiʻo kino kino, a hiki i ka hemahema ke kōkua i ka maʻi ʻāʻī a i ʻole nā ​​pilikia periodontal.

5. ʻO ke poʻo o ka migraine:Ua hōʻike kekahi mau haʻawina e hiki ke kōkua i ka hoʻohui ʻana o CoQ10 i ka hoʻohaʻahaʻa ʻana i ke alapine a me ka paʻakikī o ka migraines, e hōʻike ana he haʻahaʻa haʻahaʻa CoQ10 hiki ke lilo i kumu nui i ka ulu ʻana o kekahi poʻe.

Pehea ka lōʻihi o ka ʻike ʻana i nā pōmaikaʻi ?

Hiki ke ʻokoʻa ka manawa e ʻike ai i nā pōmaikaʻi o Coenzyme Q10 (CoQ10) ma muli o ke kūlana olakino o kēlā me kēia kanaka, ke kūlana olakino kikoʻī e kamaʻilio ʻia, a me ke ʻano o CoQ10 e hoʻohana ʻia. I kekahi mau hihia, hiki i ka poʻe ke loaʻa nā pōmaikaʻi me ka wikiwiki, ʻoiai ma nā kūlana ʻē aʻe, lōʻihi paha ka ʻike ʻana i nā hopena.

No kekahi mau maʻi e like me ka hāʻule ʻana o ka naʻau a i ʻole ke koko kiʻekiʻe, hiki ke lawe i kekahi mau pule a i ʻole mau mahina o ka hoʻonui ʻana i ka CoQ10 e nānā i ka hoʻomaikaʻi ʻana i nā hōʻailona. Ma ka ʻaoʻao ʻē aʻe, ʻike paha ka poʻe e lawe ana i ka CoQ10 no ke kākoʻo o ka ikehu maʻamau a ma ke ʻano he antioxidant paha i nā pōmaikaʻi e like me ka piʻi ʻana o nā pae ikehu a i ʻole ka hoʻomaikaʻi ʻana i ka maikaʻi holoʻokoʻa i loko o kahi manawa pōkole, i loko paha o kekahi mau pule.


Ka manawa hoʻouna: Sep-19-2024