Hoʻolako ʻia ʻo Newgreen i ka ʻili kiʻekiʻe ʻo Brown Algae Extract 98% Fucoidan Powder

Hana:

1. Hoʻomaikaʻi i ka maʻi ʻōpū

Uaʻikeʻia uaʻike nuiʻia ka hopena o ka polysaccharide i nā maʻi'ōpū ma nāʻanoʻekolu: (1) Ua loaʻa i ka polysaccharide ka hopena o ka weheʻana i ka Helicobacter pylori, ke kāohiʻana i ka hoʻonuiʻana o Helicobacter pylori a me ke kāohiʻana i kona paʻaʻana me ka mucosa'ōpū; (2) Loaʻa iā ia ka hopena o ka pale ʻana i ka ʻōpū o ka ʻōpū a me ka mālama ʻana i ka maʻi ʻōpū o ka ʻōpū, a he hopena maikaʻi hoʻi i ka waiʻona a me ka lāʻau i hoʻokomo ʻia i ka ʻeha o ka ʻōpū a me ka maʻi maʻi ʻōpū; (3) Loaʻa iā Fucoidan ka hopena anti-gastric cancer, hiki ke kāohi i ka hoʻonui ʻana o nā maʻi maʻi maʻi ʻōpū, hoʻēmi i nā hopena ʻaoʻao o ka chemotherapy, a hoʻomaikaʻi i ka maikaʻi o ke ola o nā maʻi.

2. Ka hopena anticoagulant

He nui nā hana biological ʻo Fucoidan, akā ʻo kāna hana anticoagulant ka mea i aʻo nui ʻia. Ua hōʻike ʻia nā haʻawina ʻo nā polysaccharides i unuhi ʻia mai nā ʻano liʻiliʻi ʻeleʻele moana he ʻokoʻa nā pae o ka hana anticoagulant. No ka laʻana, nā polysaccharides mai a hōʻike i kahi kiʻekiʻe o ka hana anticoagulant, a me ka hana anticoagulant o a me ka hapalua o ka mua, akā aneane ʻaʻohe hana anticoagulant.

3. Ka hopena antithrombotic

I loko o ka hoʻohālike hoʻokolohua o nā holoholona ola, ʻo ka polysaccharide o fucoidan ka hopena pale i ka thrombosis venous a me ka thrombosis arterial. ʻO Rocha et al. ʻike i ka polysaccharide ʻaʻohe hana anticoagulant in vitro, akā ua hōʻike i ka hopena antithrombotic maopopo i ke ʻano holoholona o ka hoʻokumu ʻana i ka thrombosis venous, a ua hilinaʻi ka hopena i ka manawa, a hiki i ka nui ma hope o 8h o ka hoʻokele. Ua pili paha ka hana anticoagulant o ka polysaccharide i ka hoʻoulu ʻana i ka hana o ka heparin sulfate e nā cell endothelial.

4. Ka hopena antiviral

Ua hōʻike nā haʻawina e hōʻike ana nā polysaccharides sulfated (me nā polysaccharides fucoidan) i ka hana antiviral ma vivo a me in vitro. Hayashi et al. ua aʻo i ka hopena pale o fucoidan ma ka herpes simplex virus (HSV). Ua ʻike lākou he hiki i ka fucoidan ke pale aku i nā ʻiole mai ka maʻi HSV, a ua kuhikuhi ʻia e hiki i ka fucoidan ke pale i ka maʻi HSV ma ke kāohi pololei ʻana i ka hoʻopili ʻana i ka maʻi virus a me ka hoʻonui ʻana i ka hana pale pale kino. I ka manawa like, ua ʻike ʻia ua hōʻike ka polysaccharide i ka hana antiviral e kūʻē iā HSV-1 a me HSV-2. Hidari et al. Ua hōʻike ʻia e hiki i ka fucoidan ke pale pono i ka maʻi o ka maʻi maʻi dengue ʻano 2 (DEN2), a ua hōʻike ʻo fucoidan e hoʻopaʻa i nā ʻāpana DEN2 a pili pū me kāna glycoprotein paʻa. ʻAʻohe ona hopena passivation pololei i nā virions, a ʻo kāna hana antiviral ka mea e pale ai i ka hoʻokumu ʻana o nā cytiocytes virus ma ke kāohi ʻana i ka adsorption o ka maʻi.

5. Ka hopena anti-tumor

Manaʻo ʻia ʻo Fucoidan ma ke ʻano he lāʻau anti-cancer maoli, a ua hōʻike hou ʻia kāna hana anti-tumor. ʻO Alekseyenko et al. ua aʻo i ka hana anti-tumor a fucoidan ma luna o nā ʻiole e loaʻa ana i ka Lewis lung adenocarcinoma, a hānai i ka fucoidan ma kahi maʻa o 10mg/kg i nā ʻiole, ka hopena i ka hana anti-tumor haʻahaʻa a me ka hopena anti-tumor metastasis. Ua ʻike pū kekahi mau haʻawina he 30% ka nui o ka pale ʻana o ka fucoidan ma 5 mau holoholona i loaʻa i ka sarcoma S180, a ua pau loa ka sarcoma o 2 holoholona. I loko o kahi kīʻaha petri o kahi 10,000 colon cancer cell i mālama ʻia me nā polysaccharides algae kūlohelohe i loaʻa mai ke kelp, 50 pakeneka o nā pūnaewele maʻi maʻi i make ma hope o 24 mau hola, a kokoke pau nā pūnaʻi maʻi maʻi i make ma hope o 72 hola. Hyun et al. Ua ʻike ʻia ʻo ka polysaccharide o nā algae pōhaku hiki ke pale nui i ka ulu ʻana o nā maʻi kanesa colon HCT-15. Ma hope o ka mālama ʻana i ka laina kelepona HCT-15 me ka rock algae polysaccharide, ua ʻike ʻia nā hanana apoptotic e like me ka haki ʻana o DNA, ka hōʻuluʻulu chromosome, a me ka piʻi ʻana o nā cell subdiploid i ka pae G1.

6. Nā hopena antioxidant

Ua hōʻike ʻia ka nui o nā hoʻokolohua in vitro i ka polysaccharide of rock algae he hana antioxidant koʻikoʻi, he ʻano antioxidant kūlohelohe, a hiki ke pale pono i ka maʻi i hana ʻia e nā radical manuahi. ʻO Costa et al. extracted sulfated polysaccharides mai 11 mau ʻano o ka limu tropical, ua loaʻa i nā mea a pau he hana antioxidant, hiki ke hana i nā ferrous chelates a me ka hoʻohaʻahaʻa i ka mana, 5 o lākou ka hiki ke wehe i nā radical hydroxyl, a ʻo 6 o lākou ka hiki ke wehe i nā radical peroxy. ʻO Micheline et al. Ua hōʻike ʻia e hiki i nā polysaccharides mai nā algae ke kāohi i ka hoʻokumu ʻana o ka radical hydroxyl a me superoxide radical.

7. Ka hana kino

Loaʻa iā Fucoidan nā hana palekana he nui, me ka hana anti-complement, pane anti-inflammatory a me nā hopena immunomodulatory. ʻO Tissot et al. ua hōʻoia i hiki i ka polysaccharide o fucoite ke kāohi i ka protein complement i loko o ka serum kanaka maʻamau, no laila ke keʻakeʻa nei i ka hoʻoheheʻe ʻana o nā ʻāpana koko ʻulaʻula hipa i hana ʻia e ka hoʻāla ʻana o ka complement, a ke kāohi nei i ka hoʻāla ʻana o ka complement ma ke kāohi ʻana i ka ʻanuʻu mua o ke ala hoʻāla kahiko (me ka ka ʻāpana mua o ka hoʻohui, ka ʻāpana ʻelua a me ka ʻāpana ʻehā). ʻO Yang et al. Ua ʻike ʻia e hiki i ka fucoidan ke koho koho i ka hōʻike o ka inducible nitric oxide synthase i loko o nā pūnaewele inflammatory a loaʻa iā ia ka hana anti-inflammatory. ʻO Mizuno et al. ua hoʻohana i ka ʻōnaehana co-culture o ka intestinal epithelial Caco-2 cell a me ka macrophage RAW264.7 e loiloi i ka hopena anti-inflammatory o nā mea meaʻai, a ua hōʻike nā hopena i hiki i ka polysaccharide o S. japonicum ke hoʻoulu i ka hana ʻana o ka mea necrosis tumor.α i ka RAW264.7, a laila e kaohi ai i ka hōʻike mRNA o interleukin i loko o nā pūnaewele Caco-2.

8. Hoʻonui i ka maikaʻi o ka sperm

Hiki i ka lawelawe ʻana o fucoidan ke hoʻomaikaʻi i ka maikaʻi a me ka nui o ka sperm ma o ka hoʻomaikaʻi ʻana i nā metabolites koko a me ka microbiota intestinal. Uaʻike nā mea noiʻi ma hope o ka lawelaweʻiaʻana me nā polysaccharides limu, ua hoʻonui nuiʻia nā kiʻekiʻe o nā genes e pili ana i ka spermatogenesis i nā testes o nāʻiole. I ka manawa like, aia kahi pilina maikaʻi ma waena o ka microbiota intestinal a me nā metabolites koko. Ma ka hoʻoponopono ʻana i nā mea ʻelua, ua hoʻomaikaʻi ka polysaccharide o fucoite i nā metabolites o testis, hoʻonui i ka pale antioxidant, a hoʻoponopono i ka pae hōʻike o nā genes pili i loko o nā cell germ, no laila e hāʻawi i ka spermatogenesis a me ka hoʻomaikaʻi maikaʻi.