Terbinafine Hydrochloride Babban Tsarkake API Material CAS 78628-80-5
Bayanin Samfura
Terbinafine Hydrochloridemagani ne na maganin fungal da ake amfani da shi don magance cututtuka iri-iri. Yawanci yana cikin nau'in allunan ko creams. terbinafine hydrochloride wani ingantaccen maganin fungal ne wanda ake amfani dashi don magance cututtukan fungal daban-daban. Ko yana magance ciwon ƙafar ƙafar ɗan wasa ko cututtukan ƙusa na fungal, wannan magani yana aiki ta hanyar hana samar da ergosterol kuma yana ba da zaɓuɓɓukan aikace-aikacen Topical da na baka don dacewa da inganci.
COA
| ABUBUWA | STANDARD | SAKAMAKON gwaji |
| Assay | 99% | Ya dace |
| Launi | Farin foda | Ya dace |
| wari | Babu wari na musamman | Ya dace |
| Girman barbashi | 100% wuce 80 mesh | Ya dace |
| Asarar bushewa | ≤5.0% | 2.35% |
| Ragowa | ≤1.0% | Ya dace |
| Karfe mai nauyi | ≤10.0pm | 7ppm ku |
| As | ≤2.0pm | Ya dace |
| Pb | ≤2.0pm | Ya dace |
| Ragowar magungunan kashe qwari | Korau | Korau |
| Jimlar adadin faranti | ≤100cfu/g | Ya dace |
| Yisti & Mold | ≤100cfu/g | Ya dace |
| E.Coli | Korau | Korau |
| Salmonella | Korau | Korau |
| Kammalawa | Yi daidai da ƙayyadaddun bayanai | |
| Adanawa | An adana shi a cikin Cool & Busasshen Wuri, Nisantar Haske mai ƙarfi da Zafi | |
| Rayuwar rayuwa | Shekaru 2 lokacin da aka adana da kyau | |
Aiki
1.Terbinafine hydrochloride a roba allyla antifungal. Yana da lipophilic sosai a cikin yanayi kuma yana ƙoƙarin taruwa a cikin fata, kusoshi, da kyallen takarda masu ƙiba.
2.Terbinafine · HCl memba na allyl class of antifungals, an gano shi azaman mai hanawa na ergosterol kira ta hanyar hana squalene epoxidase. Squalene epoxidase wani enzyme ne wanda kwayoyin dermatophyte na fungi suka fitar don rushe Squalene, wanda ke tsoma baki tare da aikin membrane na cell da haɗin bango.
3.Terbinafine hydrochloride yana da tasirin fungicidal akan fungi na fata da kuma tasirin hanawa akan Candida albicans. Ya dace da cututtuka na fata da ƙusa wanda ke haifar da fungi na sama, irin su ringworm, tsutsotsi na jiki, tsutsotsi na femur, tsutsotsi na ƙafafu, tsutsotsi na ƙusa da Candida albicans kamuwa da fata ta hanyar Trichophyton rubrum, Microsporum canis. da kuma Flocculus epidermidis.
Aikace-aikace
Terbinafine hydrochloride fari ne mai kyau crystalline foda wanda yake da yardar kaina mai narkewa a cikin methan da dichlorome, mai narkewa a cikin ethanol, kuma dan kadan mai narkewa cikin ruwa. Kamar sauran allylamines, terbinafine yana hana ergosterol kira ta hanyar hana squalene epoxidase,
wani enzyme wanda ke cikin hanyar haɗin ƙwayar fungal cell membrane. Saboda terbinafine yana hana juyawa na squalene zuwa lanosterol, ergosterol ba zai iya haɗawa ba. Ana tsammanin wannan zai canza canjin kwayar halitta, yana haifar da kwayar cutar fungal.
1. Terbinafine Hcl ya fi tasiri akan ƙungiyar dermatophyte na fungi.
2. A matsayin 1% cream ko foda, ana amfani dashi a kai a kai don cututtukan fata na fata kamar jock itch (tinea cruris),
ƙafar 'yan wasa (tinea pedis), da sauran nau'ikan ringworm (tinea corporis). Terbinafine cream yana aiki a cikin kusan rabin lokacin da ake buƙata
da sauran antifungals.
3. Ana yawan rubuta allunan 250mg na baka don maganin onychomycosis, ciwon ƙusa na fungal, yawanci ta hanyar dermatophyte.
ko Candida jinsuna. Cututtukan ƙusa na ƙusa suna zurfi a ƙarƙashin ƙusa a cikin cuticle wanda aka yi amfani da shi a zahiri
ba su iya shiga cikin isassun adadi. Allunan na iya, da wuya, suna haifar da hepatotoxicity, don haka ana gargadin marasa lafiya game da wannan kuma
ana iya sa ido tare da gwajin aikin hanta. An yi nazarin madadin hanyoyin sarrafa baki.
4. Terbinafine na iya haifar da ko kara tsananta yanayin lupus erythematosus na subacute cutaneous. Mutanen da ke da lupus erythematosus ya kamata
da farko tattauna yiwuwar kasada tare da likitan su kafin fara far.
Samfura masu dangantaka
Newgreen factory kuma yana samar da amino acid kamar haka:
Kunshin & Bayarwa
