Cyclosporin Newgreen Supply High Quality APIs 99% Cyclosporin Powder
Product Description
Cyclosporin is an immunosuppressant used primarily to prevent organ transplant rejection and treat certain autoimmune diseases. It is extracted from soil fungi and has the effect of selectively inhibiting T cell activation.
Main Mechanics
Inhibit T cell activation:
Cyclosporin inhibits the activity of calmodulin-dependent phosphatase (calcineurin) by binding to cyclophilin-binding protein in cells, thereby preventing the activation and proliferation of T cells and reducing immune response.
Indications
Cyclosporin is mainly used in the following situations:
Organ Transplant: Used to prevent rejection of organs such as kidneys, livers, and hearts after transplantation, usually in combination with other immunosuppressants.
Autoimmune diseases: Can be used to treat autoimmune diseases such as rheumatoid arthritis, psoriasis, Sjögren's syndrome, etc.
Other indications: In some cases, Cyclosporin is also used to treat severe allergic reactions and certain skin conditions.
COA
| Items | Specifications | Results |
| Appearance | White powder | Complies |
| Order | Characteristic | Complies |
| Assay | ≥99.0% | 99.8% |
| Tasted | Characteristic | Complies |
| Loss on Drying | 4-7(%) | 4.12% |
| Total Ash | 8% Max | 4.85% |
| Heavy Metal | ≤10(ppm) | Complies |
| Arsenic(As) | 0.5ppm Max | Complies |
| Lead(Pb) | 1ppm Max | Complies |
| Mercury(Hg) | 0.1ppm Max | Complies |
| Total Plate Count | 10000cfu/g Max. | 100cfu/g |
| Yeast & Mould | 100cfu/g Max. | ＞20cfu/g |
| Salmonella | Negative | Complies |
| E.Coli. | Negative | Complies |
| Staphylococcus | Negative | Complies |
| Conclusion | Qualified | |
| Storage | Store in a well-closed place with constant low temperature and no direct sun light. | |
| Shelf life | 2 years when properly stored | |
Function
Side Effect
Cyclosporin may cause some side effects, including:
Nephrotoxicity: May cause renal impairment and requires regular monitoring of renal function.
High Blood Pressure: Cyclosporin use may cause an increase in blood pressure.
Risk of infection: Due to immunosuppression, patients may be more susceptible to infections.
Other side effects: such as headache, gastrointestinal discomfort, gingival hyperplasia, etc.
Notes
Monitoring: When using Cyclosporin, renal function, blood pressure and blood drug concentrations should be monitored regularly.
Drug Interactions: Cyclosporin may interact with other drugs. You should inform your doctor of all the drugs you are taking before using it.
Pregnancy and Breast-feeding: Cyclosporin should be used with caution during pregnancy and breast-feeding and consultation with a physician is required.
Package & Delivery
Function
Nerol’s Function
Nerol is a natural monoterpene alcohol with the chemical formula C10H18O. It is mainly found in the essential oils of various plants, such as rose, lemongrass and mint. Nerol has many functions and applications, mainly including the following aspects:
1. Fragrance and Aroma: Nerol has a fresh, floral smell and is often used in perfumes and fragrances as an aroma ingredient to increase the appeal of the product. It can add soft floral notes to perfumes.
2. Cosmetics: In the cosmetics industry, Nerol is used as a fragrance ingredient and is commonly found in products such as skin care products, shampoos and shower gels to enhance the user experience.
3. Food additive: Nerol can be used as a food flavoring and added to beverages, candies and other foods to provide a floral flavor.
4. Biological activity: Studies have shown that Nerol may have antibacterial, antioxidant and anti-inflammatory biological activities, which makes it of interest in drug development and health supplements.
5. Insect Repellent: Nerol has been found to have some insect repellent effects and can be used as a natural insect repellent to help prevent pest infestations.
6. Aromatherapy: In aromatherapy, Nerol is used for relaxation and stress relief due to its soothing aroma, helping to improve mood and psychological state.
In conclusion, Nerol plays an important role in many fields such as perfume, cosmetics, food, pharmaceutical research and aromatherapy due to its unique aroma and multiple biological activities.
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