Chenodeoxycholic Acid 98% Manufacturer Newgreen Chenodeoxycholic Acid 98% Powder Supplement
Product Description
Chenodeoxycholic acid (also known as chenodesoxycholic acid and chenocholic acid) is a bile acid. It occurs as a white crystalline substance insoluble in water but soluble in alcohol and acetic acid, with melting point at 165-167 °C. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the 4 main organic acids produced by the liver. For the prevention and treatment of cholesterol cholelithiasis and Depressing blood-fat Ingredients, cholelithiasis and mixed cholelithiasis also have a certain effect.
COA
| Items | Specifications | Results |
| Appearance | White Fine Powder | White Fine Powder |
| Assay | 98% | Pass |
| Odor | None | None |
| Loose Density(g/ml) | ≥0.2 | 0.26 |
| Loss on Drying | ≤8.0% | 4.51% |
| Residue on Ignition | ≤2.0% | 0.32% |
| PH | 5.0-7.5 | 6.3 |
| Average molecular weight | <1000 | 890 |
| Heavy Metals(Pb) | ≤1PPM | Pass |
| As | ≤0.5PPM | Pass |
| Hg | ≤1PPM | Pass |
| Bacterial Count | ≤1000cfu/g | Pass |
| Colon Bacillus | ≤30MPN/100g | Pass |
| Yeast & Mold | ≤50cfu/g | Pass |
| Pathogenic Bacteria | Negative | Negative |
| Conclusion | Conform with specification | |
| Shelf life | 2 years when properly stored | |
Function
1.Medicine Raw Material, Chenodeoxycholic acid has been used as medical therapy to dissolve gallstones;
2. Brain Health Care Material, Chenodeoxycholic acid can be used in the treatment of cerebrotendineous xanthomatosis;
3. Active Pharmaceutical Ingredients, It can treatment for Hepatitis C infection that combines chenodeoxycholic acid with bezafibrate.
Application
1. It is one of the most widely used drugs to treat gallstones in the world. For cholesterol gallstones, it is especially suitable for patients with good gallbladder function and gallbladder cholesterol stone diameter less than 2cm. The mechanism of action is to reduce the saturation of cholesterol in bile, restore the lipids to the micellar state, and cholesterol is in an unsaturated state, thus promoting the dissolution and shedding of cholesterol in stones.
2. Large doses (10-15 mg/kg daily) can inhibit the synthesis of cholesterol and increase the secretion of bile in patients with cholelithiasis, but the secretion of bile salts and phospholipids remains unchanged.
3. It is an important raw material for the synthesis of ursodeoxycholic acid (UDCA) and other steroid compounds.
4. Study on physiological and pathological mechanism of liver and bile Because of its important effects on bile composition and gallstone formation and dissolution Boosting immunity extract, it has been used to study physiological processes such as cholesterol metabolism and bile acid metabolic balance in the hepatobiliary system and the pathogenesis of gallstones.
5. It is decomposed into Lithocholic acid (LCA) by 7α-dehydroxylation of the coliform flora in the intestine. This process can be used to study the metabolism of intestinal flora and the relationship between flora and host metabolism.
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