99% Apramycin Sulfate Powder CAS 41194-16-5 Antibacterial Apramycin Sulfate
Product Description
Apramycin Sulfate is an aminoglycoside antibiotic that exhibits its pharmacological activity by binding to the bacterial ribosomes, specifically to the deep groove of the 16S rRNA, inhibiting protein synthesis and ultimately leading to bacterial cell death.
COA
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ITEMS |
STANDARD |
TEST RESULT |
| Assay | 99% | Conforms |
| Color | White powder | Conforms |
| Odor | No special smell | Conforms |
| Particle size | 100% pass 80mesh | Conforms |
| Loss on drying | ≤5.0% | 2.35% |
| Residue | ≤1.0% | Conforms |
| Heavy metal | ≤10.0ppm | 7ppm |
| As | ≤2.0ppm | Conforms |
| Pb | ≤2.0ppm | Conforms |
| Pesticide residue | Negative | Negative |
| Total plate count | ≤100cfu/g | Conforms |
| Yeast & Mold | ≤100cfu/g | Conforms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
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Conclusion |
Conform with Specification |
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Storage |
Stored in Cool & Dry Place, Keep Away From Strong Light And Heat |
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Shelf life |
2 years when properly stored |
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Function
1.Antibacterial Activity: The primary function of Apramycin Sulfate is to inhibit bacterial growth by disrupting protein synthesis through its interaction with the bacterial ribosome.
2.Spectrum of Activity: It possesses a broad spectrum of activity against Gram-negative bacteria, including many pathogens that are resistant to other antibiotics.
3.Post-Antibiotic Effect: Apramycin Sulfate exhibits a post-antibiotic effect, meaning that it can continue to suppress bacterial growth even after its concentration in the body falls below the minimum inhibitory concentration.
Application
1.Therapeutic Use: Apramycin Sulfate is primarily applied in veterinary medicine as an antibacterial agent for the treatment of infections caused by susceptible bacteria, particularly in swine, poultry, and cattle.
2.Agricultural Practice: It is also utilized in agriculture to control and prevent bacterial diseases in livestock, ensuring animal health and productivity.
3.Research Purposes: In research settings, Apramycin Sulfate serves as a valuable tool for studying the mechanisms of aminoglycoside antibiotics and their interactions with bacterial ribosomes.
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